Featured Research

from universities, journals, and other organizations

Johns Hopkins Researchers Find More Extensive Bone Defects Caused By Bladder Exstrophy

Date:
December 24, 2001
Source:
Johns Hopkins Medical Institutions
Summary:
Researchers at Johns Hopkins Children's Center and St. Vincent de Paul's Hospital in Paris have learned that bone defects associated with classic bladder exstrophy are more extensive than previously thought. Their findings, reported in this month's Urology, will enable surgeons to better correct these bone defects that cause the bladder to develop outside of the body.

Researchers at Johns Hopkins Children's Center and St. Vincent de Paul's Hospital in Paris have learned that bone defects associated with classic bladder exstrophy are more extensive than previously thought. Their findings, reported in this month's Urology, will enable surgeons to better correct these bone defects that cause the bladder to develop outside of the body.

"We believe surgeons already do a great job," said Children's Center Director of Pediatric Urology John P. Gearhart, M.D., who directed the research. "But this information will further help the few surgeons who do this procedure to provide a long-lasting fix for these children."

Classic bladder exstrophy, which occurs in approximately one of every 30,000 live births, is a defect that affects an infant's pelvic bones, genitorurinary ducts, and leaves a hole in the abdominal wall through which the bladder emerges.

The researchers reviewed abdominal CT scans from seven infants with classic bladder exstrophy as well as CT scans of 26 infants who had them taken for other reasons. The team then compared the geometry of pelvic girdle bones in the bladder exstrophy group of infants with the normal group, looking for statistically significant differences.

The team learned that pelvic girdle bone defects in bladder exstrophy cases were more extensive than previously thought. Among the most pronounced differences were an outward flare of the upper part of the hip bone and a rotation of the entire pelvic girdle from the bottom forward.

Gearhart says the research broadens surgeons' understanding of those bone defects so that more effective adjustments can be made in realigning and repositioning bones of the pelvis. Gearhart also says the findings suggest a possible explanation for the mysterious muscle weakness some women born with bladder exstrophy have shortly after they give birth.

Researchers at the Johns Hopkins School of Medicine and the Department of Pediatric Surgery at St. Vincent de Paul's Hospital in Paris also contributed to the study. It was funded by grants from the National Institutes of Health and the Johns Hopkins Department of Urology.


Story Source:

The above story is based on materials provided by Johns Hopkins Medical Institutions. Note: Materials may be edited for content and length.


Cite This Page:

Johns Hopkins Medical Institutions. "Johns Hopkins Researchers Find More Extensive Bone Defects Caused By Bladder Exstrophy." ScienceDaily. ScienceDaily, 24 December 2001. <www.sciencedaily.com/releases/2001/12/011224082546.htm>.
Johns Hopkins Medical Institutions. (2001, December 24). Johns Hopkins Researchers Find More Extensive Bone Defects Caused By Bladder Exstrophy. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2001/12/011224082546.htm
Johns Hopkins Medical Institutions. "Johns Hopkins Researchers Find More Extensive Bone Defects Caused By Bladder Exstrophy." ScienceDaily. www.sciencedaily.com/releases/2001/12/011224082546.htm (accessed July 25, 2014).

Share This




More Health & Medicine News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
Too Few Teens Receiving HPV Vaccination, CDC Says

Too Few Teens Receiving HPV Vaccination, CDC Says

Newsy (July 24, 2014) The Centers for Disease Control and Prevention is blaming doctors for the low number of children being vaccinated for HPV. Video provided by Newsy
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile: iPhone Android Web
          Follow: Facebook Twitter Google+
          Subscribe: RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins