Featured Research

from universities, journals, and other organizations

Statin Drugs May Lower Risk Of Alzheimer’s

Date:
April 18, 2002
Source:
American Academy Of Neurology
Summary:
Taking the cholesterol-lowering drugs called statins may reduce the risk of developing Alzheimer’s disease, according to research presented during the American Academy of Neurology’s 54th Annual Meeting in Denver. The study found that taking statins was associated with a 79-percent reduction in the risk of developing Alzheimer’s disease.

DENVER, CO – Taking the cholesterol-lowering drugs called statins may reduce the risk of developing Alzheimer’s disease, according to research presented during the American Academy of Neurology’s 54th Annual Meeting in Denver, Colo., April 13-20, 2002.

Related Articles


The study found that taking statins was associated with a 79-percent reduction in the risk of developing Alzheimer’s disease, according to the study’s lead author, neurologist and epidemiologist Robert C. Green, MD, MPH, of Boston University School of Medicine.

“This study confirms and extends previous reports and is the largest study on this topic in the U.S.,” Green said. “It is also the first to include a large number of African-American families.”

Researchers studied 2,581 people from more than 800 families, enrolled over six years at 15 medical centers. They examined risk factors and medication history in 912 people with probable or definite Alzheimer’s disease and 1,669 of their family members who did not have dementia. The results were adjusted for age, sex, education, and history of heart disease, stroke and diabetes.

The relationship between statins and risk of Alzheimer’s was no different for people with the gene variant associated with an increased risk of Alzheimer’s, apolipoprotein E ?4, or apoE-?4. The relationship between statins and Alzheimer’s was also the same for whites as it was for African Americans, who have a higher risk of developing the disease.

Statins lower levels of low-density lipoprotein (LDL) cholesterol by blocking the production of a liver enzyme used by the body to make cholesterol. In this study, cholesterol-lowering drugs other than statins were not associated with a reduced risk of Alzheimer’s. There was also no difference between the use of natural and synthetic statins.

The study was supported by grants from the National Institute on Aging and the National Human Genome Research Institute of the National Institutes of Health. These data were collected as part of an ongoing genetic epidemiology study based at Boston University School of Medicine and led by Lindsay Farrer, PhD.

The American Academy of Neurology, an association of more than 18,000 neurologists and neuroscience professionals, is dedicated to improving patient care through education and research.

For more information about the American Academy of Neurology, visit its web site at http://www.aan.com/.


Story Source:

The above story is based on materials provided by American Academy Of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy Of Neurology. "Statin Drugs May Lower Risk Of Alzheimer’s." ScienceDaily. ScienceDaily, 18 April 2002. <www.sciencedaily.com/releases/2002/04/020417070836.htm>.
American Academy Of Neurology. (2002, April 18). Statin Drugs May Lower Risk Of Alzheimer’s. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2002/04/020417070836.htm
American Academy Of Neurology. "Statin Drugs May Lower Risk Of Alzheimer’s." ScienceDaily. www.sciencedaily.com/releases/2002/04/020417070836.htm (accessed October 24, 2014).

Share This



More Health & Medicine News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Breakfast Debate: To Eat Or Not To Eat?

Breakfast Debate: To Eat Or Not To Eat?

Newsy (Oct. 23, 2014) Conflicting studies published in the same week re-ignited the debate over whether we should be eating breakfast. Video provided by Newsy
Powered by NewsLook.com
Ebola Fears Keep Guinea Hospitals Empty

Ebola Fears Keep Guinea Hospitals Empty

AP (Oct. 23, 2014) Fears of Ebola are keeping doctors and patients alike away from hospitals in the West African nation of Guinea. (Oct. 23) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins