Featured Research

from universities, journals, and other organizations

Bandage Could Repair Damaged Tissues

Date:
June 14, 2002
Source:
University Of Wisconsin-Madison
Summary:
John Kao's invention is sort of like a molecular version of Jell-O salad -- it's made from gelatin, turns into a solid and has stuff suspended in it. But, instead of containing marshmallows and chunks of fruit, it has molecules and cells that repair damaged tissue.

John Kao's invention is sort of like a molecular version of Jell-O salad -- it's made from gelatin, turns into a solid and has stuff suspended in it. But, instead of containing marshmallows and chunks of fruit, it has molecules and cells that repair damaged tissue.

By using modified gelatin and polymers, Kao, a University of Wisconsin-Madison pharmaceutical science and biomedical engineering professor, has developed a bandage that contains the molecular structure needed to help cells heal an injury.

According to Kao, the body's cells grow inside three-dimensional scaffolding that also contain nutrients, proteins and other molecules necessary for life. These molecules interact with the cells, sending them signals that control their activities, growth and regeneration. But according to Kao, damage to the scaffolding could threaten cellular activity.

Any bodily injury -- a cut, burn, fracture -- razes the molecular support for cells, thereby disrupting their functions. Treating these injuries, Kao says, requires rebuilding the scaffolding where the cell and molecules interact. "Most bandages don't do this," he explains. "They simply cover up the wound."

Kao's bandage, on the other hand, includes a synthetic version of the same structure cells use to grow and carry out their functions. It can contain new cells, molecules and even drug compounds needed to heal an injury. "The technology attempts to mimic the natural cellular environment," he says. "That's important because it enhances our ability to repair and regenerate damaged tissue."

The product initially takes a liquid form and then solidifies. "Unlike bandages that have to be cut to shape, doctors can pour this solution over an area, even something like a damaged internal organ, and it will set in place," Kao says. Just as Jell-O thickens when refrigerated, Kao's substance turns into a flexible, degradable solid when exposed to ultraviolet light. Because it's highly porous, the bandage can also absorb excess fluids.

By varying the chemistry of the bandage, Kao says they can control the interactions among the molecules and cells, as well as the rate of degradation. "The product is highly versatile depending on the application," he adds. He thinks it might even provide a method for transplanting stem cells to regenerate damaged or diseased tissue.

Kao's bandage is patented by the Wisconsin Research Alumni Foundation, a nonprofit organization that manages the intellectual property in the interest of UW-Madison.


Story Source:

The above story is based on materials provided by University Of Wisconsin-Madison. Note: Materials may be edited for content and length.


Cite This Page:

University Of Wisconsin-Madison. "Bandage Could Repair Damaged Tissues." ScienceDaily. ScienceDaily, 14 June 2002. <www.sciencedaily.com/releases/2002/06/020614074914.htm>.
University Of Wisconsin-Madison. (2002, June 14). Bandage Could Repair Damaged Tissues. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2002/06/020614074914.htm
University Of Wisconsin-Madison. "Bandage Could Repair Damaged Tissues." ScienceDaily. www.sciencedaily.com/releases/2002/06/020614074914.htm (accessed July 25, 2014).

Share This




More Health & Medicine News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
Too Few Teens Receiving HPV Vaccination, CDC Says

Too Few Teens Receiving HPV Vaccination, CDC Says

Newsy (July 24, 2014) The Centers for Disease Control and Prevention is blaming doctors for the low number of children being vaccinated for HPV. Video provided by Newsy
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile: iPhone Android Web
          Follow: Facebook Twitter Google+
          Subscribe: RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins