Featured Research

from universities, journals, and other organizations

Higher Nocturnal Blood Pressure Predictive Of Kidney Disease In Diabetes

Date:
September 12, 2002
Source:
Northwestern University
Summary:
Monitoring nighttime blood pressure is a simple, painless and noninvasive method of identifying patients with type 1 diabetes who are at increased risk for kidney disease, according to a study published in the Sept. 12 issue of The New England Journal of Medicine.

Monitoring nighttime blood pressure is a simple, painless and noninvasive method of identifying patients with type 1 diabetes who are at increased risk for kidney disease, according to a study published in the Sept. 12 issue of The New England Journal of Medicine.

Related Articles


Daniel Batlle, M.D., professor of medicine at The Feinberg School of Medicine at Northwestern University and researchers from Spain showed that in persons with type 1 diabetes, an increase in systolic blood pressure during sleep precedes the development of microalbuminuria -- or a protein called albumin in the urine -- a condition that is predictive of kidney disease.

In their prospective study, the investigators used 24-hour ambulatory blood pressure monitoring in 75 adolescents and young adults with type 1 diabetes who had normal blood pressure and urinary albumin excretion levels at enrollment. Over a follow-up period of five years, 14 of the patients had developed microalbuminuria.

This group also had nighttime systolic blood pressure that was significantly higher than those in study participants with normal urinary albumin levels. By contrast, in those whose blood pressure during sleep decreased normally, the progression from normal albumin excretion to microalbuminuria appeared to be less likely.

Blood pressure has a normal circadian rhythm and varies depending on levels of stress and physical activity.

"Thus, blood pressure measured randomly at the physician's office cannot fully reflect blood pressure levels around the clock, particularly when it is close to the normal range at earlier stages of diabetes," Batlle said.

The researchers said that an increase in nighttime systolic pressure appears to be the earliest detectable manifestation of altered blood pressure regulation in patients with type 1 diabetes and may provide a good way for choosing or avoiding unnecessary therapies to prevent microalbuminuria and kidney disease in patients with type 1 diabetes.


Story Source:

The above story is based on materials provided by Northwestern University. Note: Materials may be edited for content and length.


Cite This Page:

Northwestern University. "Higher Nocturnal Blood Pressure Predictive Of Kidney Disease In Diabetes." ScienceDaily. ScienceDaily, 12 September 2002. <www.sciencedaily.com/releases/2002/09/020912065819.htm>.
Northwestern University. (2002, September 12). Higher Nocturnal Blood Pressure Predictive Of Kidney Disease In Diabetes. ScienceDaily. Retrieved April 18, 2015 from www.sciencedaily.com/releases/2002/09/020912065819.htm
Northwestern University. "Higher Nocturnal Blood Pressure Predictive Of Kidney Disease In Diabetes." ScienceDaily. www.sciencedaily.com/releases/2002/09/020912065819.htm (accessed April 18, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, April 18, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Our Love Of Puppy Dog Eyes Explained By Science

Our Love Of Puppy Dog Eyes Explained By Science

Newsy (Apr. 17, 2015) Researchers found a spike in oxytocin occurs in both humans and dogs when they gaze into each other&apos;s eyes. Video provided by Newsy
Powered by NewsLook.com
Scientists Find Link Between Gestational Diabetes And Autism

Scientists Find Link Between Gestational Diabetes And Autism

Newsy (Apr. 17, 2015) Researchers who analyzed data from over 300,000 kids and their mothers say they&apos;ve found a link between gestational diabetes and autism. Video provided by Newsy
Powered by NewsLook.com
Video Messages Help Reassure Dementia Patients

Video Messages Help Reassure Dementia Patients

AP (Apr. 17, 2015) Family members are prerecording messages as part of a unique pilot program at the Hebrew Home in New York. The videos are trying to help victims of Alzheimer&apos;s disease and other forms of dementia break through the morning fog of forgetfulness. (April 17) Video provided by AP
Powered by NewsLook.com
Boy or Girl? Intersex Awareness Is on the Rise

Boy or Girl? Intersex Awareness Is on the Rise

AP (Apr. 17, 2015) At least 1 in 5,000 U.S. babies are born each year with intersex conditions _ ambiguous genitals because of genetic glitches or hormone problems. Secrecy and surgery are common. But some doctors and activists are trying to change things. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins