Featured Research

from universities, journals, and other organizations

Virginia Commonwealth University Scientists Growing Synthetic Blood Vessels

Date:
November 27, 2002
Source:
Virginia Commonwealth University
Summary:
Traditional heart bypass surgeries require using veins from the leg to replace damaged blood vessels. Using a nanotechnology developed by Virginia Commonwealth University researchers, doctors soon could be using artificial blood vessels grown in a laboratory to help save half a million lives every year.

RICHMOND, Va. – Traditional heart bypass surgeries require using veins from the leg to replace damaged blood vessels. Using a nanotechnology developed by Virginia Commonwealth University researchers, doctors soon could be using artificial blood vessels grown in a laboratory to help save half a million lives every year.

The new technology produces a natural human blood vessel grown around a scaffold, or tube, made of collagen. Using a process called electrospinning, VCU scientists are making tubes as small as one millimeter in diameter. That’s more than four times smaller than the width of a drinking straw and six times smaller than the smallest commercially available vascular graft.

VCU Biomedical Engineer Gary L. Bowlin, Ph.D., said patients don’t always have enough spare veins for a heart bypass, and even when they do, complications and failures often result because they are not compatible. “So what’s really needed is a blood vessel you can pull off the shelf,” said Bowlin.

After the scaffold is spun, smooth muscle cells are “seeded” or placed on its surface in a laboratory. The cells grow and within three-to-six weeks the tissue-engineered blood vessel is ready to implant.

Unlike current synthetic plastic blood vessels, collagen is a natural component of the body, allowing cells to grow on its surface and avoid rejection. “The cells are in a happy environment and they’re just going to stay and think ‘I’m a blood vessel, I’m going to act like a blood vessel,’” said Bowlin.

The collagen scaffold is biodegradable and eventually is replaced by the body. Pre-made blood vessels could be made available to emergency rooms where every second counts. Other applications include pediatric surgery where implanted blood vessels must grow with the patient and diabetic patients who often lose blood vessels to vascular disease.

The same collagen electrospinning technology can also be used to regenerate or replace skin, bone, nerves, muscles and even repair spinal cord injuries, according to co-inventor Gary E. Wnek, Ph.D., a VCU chemical engineer. “Anything you want to repair can start from a scaffold. We’re very excited about the potential,” said Wnek.

Practical applications of the new technology could be commercially available within three years.

About VCU: Virginia Commonwealth University is ranked by the Carnegie Foundation as one of the nation’s top research universities. Located on two campuses in Richmond, Va., VCU enrolls 26,000 students in more than 160 undergraduate, graduate, professional, doctoral and post-graduate certificate degree programs at 11 schools and one college. Sixteen graduate and professional programs have been ranked by U.S. News & World Report as among the best of their kind in the nation. The VCU Health System is one of the leading academic medical centers in the country. VCU recently launched VCU Life Sciences, a comprehensive undergraduate and graduate program involving academic and medical faculty. In addition, the university is developing the Virginia Biotechnology Research Park in collaboration with business, civic and government leaders. For more, see http://www.vcu.edu.


Story Source:

The above story is based on materials provided by Virginia Commonwealth University. Note: Materials may be edited for content and length.


Cite This Page:

Virginia Commonwealth University. "Virginia Commonwealth University Scientists Growing Synthetic Blood Vessels." ScienceDaily. ScienceDaily, 27 November 2002. <www.sciencedaily.com/releases/2002/11/021126210341.htm>.
Virginia Commonwealth University. (2002, November 27). Virginia Commonwealth University Scientists Growing Synthetic Blood Vessels. ScienceDaily. Retrieved September 2, 2014 from www.sciencedaily.com/releases/2002/11/021126210341.htm
Virginia Commonwealth University. "Virginia Commonwealth University Scientists Growing Synthetic Blood Vessels." ScienceDaily. www.sciencedaily.com/releases/2002/11/021126210341.htm (accessed September 2, 2014).

Share This




More Health & Medicine News

Tuesday, September 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Get on Your Bike! London Cycling Popularity Soars Despite Danger

Get on Your Bike! London Cycling Popularity Soars Despite Danger

AFP (Sep. 1, 2014) Wedged between buses, lorries and cars, cycling in London isn't for the faint hearted. Nevertheless the number of people choosing to bike in the British capital has doubled over the past 15 years. Duration: 02:27 Video provided by AFP
Powered by NewsLook.com
Can You Train Your Brain To Eat Healthy?

Can You Train Your Brain To Eat Healthy?

Newsy (Sep. 1, 2014) New research says if you condition yourself to eat healthy foods, eventually you'll crave them instead of junk food. Video provided by Newsy
Powered by NewsLook.com
We've Got Mites Living In Our Faces And So Do You

We've Got Mites Living In Our Faces And So Do You

Newsy (Aug. 30, 2014) A new study suggests 100 percent of adult humans (those over 18 years of age) have Demodex mites living in their faces. Video provided by Newsy
Powered by NewsLook.com
Liberia Continues Fight Against Ebola

Liberia Continues Fight Against Ebola

AFP (Aug. 30, 2014) Authorities in Liberia try to stem the spread of the Ebola epidemic by raising awareness and setting up sanitation units for people to wash their hands. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins