Featured Research

from universities, journals, and other organizations

Genetic Risks For Disease Often Missing From Patient Charts

Date:
August 13, 2003
Source:
Northwestern University
Summary:
Standard history-taking in internal medicine practices may not fully capture patients' risks for developing certain diseases and internists may lose opportunities to provide preventive medical recommendations, according to a study from Northwestern University.

Standard history-taking in internal medicine practices may not fully capture patients' risks for developing certain diseases and internists may lose opportunities to provide preventive medical recommendations, according to a study from Northwestern University.

Related Articles


Researchers on the study included Theresa M. Frezzo; Wendy S. Rubinstein, M.D.; Daniel Dunham, M.D.; and Kelly E. Ormond of the Feinberg School of Medicine at Northwestern University.

Results from the study showed that about 80 percent of patients in an internal medicine practice were at moderate or high risk for certain adult-onset conditions with known genetic components -- such as breast/ovarian cancer, prostate cancer, colon cancer, heart disease, non-insulin dependent diabetes mellitus and conditions causing blood clotting or stroke.

Using an oral "pedigree" or written questionnaire, the researchers identified twice as many individuals at increased risk than was documented in patient charts. The pedigree is a medical diagram of a family tree used to help make diagnosis of genetic disease, determine risk for developing genetic disease or determine risk for having a child with a genetic disease.

The study, which was published in a recent issue of Genetics in Medicine, was based on an analysis of data -- in either a family history questionnaire or in a three-generation pedigree interview conducted by a genetic counselor -- compared with information recorded on patient charts. Three-generation pedigrees include health information on parents and siblings, aunts and uncles and cousins and grandparents.

Since a family history of adult-onset disease is one of the largest risk factors for developing a condition in adulthood, knowing a patient's family history, and, therefore, the patient's risk, may influence decisions about potential genetic testing, as well as treatments or lifestyle changes that may significantly reduce the occurrence of premature illness and death.

Yet, limited training in genetics and brief patient visits curb most physicians' routine use of a comprehensive three-generation pedigree, Frezzo and colleagues said.

"Recording the medical family history should be a component of any preventive healthcare risk assessment. As genetic risk factors are better understood and more interventions to reduce risk become available, evaluation of the genetic family history may become an integral part of public and preventive medicine," the researchers said.

They believe that more research and education on the benefits of using family history questionnaires and three-generation pedigrees will expedite incorporation of these tools into primary medicine, resulting in improved prevention, diagnostic and treatment strategies.

Frezzo is the research coordinator and a genetic counselor for the NUgene Project at the Center for Genetic Medicine at the Feinberg School. Ormond is assistant professor of medicine, director of the Graduate Program in Genetic Counseling, and a member of the Center for Genetic Medicine at the Feinberg School. Rubinstein is assistant professor of medicine at the Feinberg School and a researcher in the Center for Medical Genetics at Evanston Northwestern Healthcare. Dunham is assistant professor of medicine at the Feinberg School and a general internist at the Northwestern Medical Faculty Foundation.


Story Source:

The above story is based on materials provided by Northwestern University. Note: Materials may be edited for content and length.


Cite This Page:

Northwestern University. "Genetic Risks For Disease Often Missing From Patient Charts." ScienceDaily. ScienceDaily, 13 August 2003. <www.sciencedaily.com/releases/2003/08/030813071209.htm>.
Northwestern University. (2003, August 13). Genetic Risks For Disease Often Missing From Patient Charts. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2003/08/030813071209.htm
Northwestern University. "Genetic Risks For Disease Often Missing From Patient Charts." ScienceDaily. www.sciencedaily.com/releases/2003/08/030813071209.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins