Featured Research

from universities, journals, and other organizations

'Dry Eye' In Women May Be Linked To Sex Hormones

Date:
February 12, 2004
Source:
Journal Of The American Medical Association
Summary:
Women whose ovaries prematurely cease functioning may be at a greater risk for dry eye symptoms, according to an article in the February issue of The Archives of Ophthalmology, one of the JAMA/Archives journals.

CHICAGO – Women whose ovaries prematurely cease functioning may be at a greater risk for dry eye symptoms, according to an article in the February issue of The Archives of Ophthalmology, one of the JAMA/Archives journals.

Premature ovarian failure (POF) occurs when the ovaries stop functioning normally in women under 40 years and affected approximately 1 percent of women in a large study, according to the article. Women with POF experience the same symptoms of estrogen deficiency as postmenopausal women, including hot flashes, night sweats, fatigue, and mood swings, and have an increased risk of cardiovascular disease and osteoporosis. Androgen deficiency (low levels of the male hormone androgen), has been associated with dry eye, a condition affecting an estimated 15 percent of people in the United States aged 65 to 84 years. Reduced tear production and poor tear quality (causing moisture to evaporate from the surface of the eye too quickly) can result in dry eye. Because women with POF also have androgen deficiency, it is possible that POF and dry eye symptoms may be associated.

Janine A. Smith, M.D., of the National Eye Institute, Bethesda, Md., and colleagues investigated the association between POF and dry eye. They examined 65 women with POF and 36 women without POF for symptoms of dry eye.

The researchers found the proportion of patients that met dry eye diagnostic criteria was significantly greater among women with POF than women without POF (20 percent vs. 3 percent).

"Women with POF were more likely to exhibit ocular surface damage and symptoms of dry eye than age-matched controls. They were not, however, more likely to have reduced tear production," the authors write. "These data provide further evidence of the multifaceted role of sex hormones in the health and disease of the ocular surface."

###

(Arch Ophthalmol. 2004;122:151-156. Available post-embargo at http://archophthalmol.com)

Editorial: Hormonal Deficiencies and Dry Eye

In an accompanying editorial, Stephen C. Pflugfelder, M.D., of Houston, writes, "The study by Smith et al did not determine which hormones are most important in maintaining [balanced moisture on the surface of the eye] or whether deficiencies of androgen, estrogen, or both hormones were responsible for the observed ocular surface abnormalities. Additional studies of patients with POF could answer these questions."

(Arch Ophthalmol. 2004:122:273-274. Available post-embargo at http://archophtalmol.com)


Story Source:

The above story is based on materials provided by Journal Of The American Medical Association. Note: Materials may be edited for content and length.


Cite This Page:

Journal Of The American Medical Association. "'Dry Eye' In Women May Be Linked To Sex Hormones." ScienceDaily. ScienceDaily, 12 February 2004. <www.sciencedaily.com/releases/2004/02/040212084949.htm>.
Journal Of The American Medical Association. (2004, February 12). 'Dry Eye' In Women May Be Linked To Sex Hormones. ScienceDaily. Retrieved August 22, 2014 from www.sciencedaily.com/releases/2004/02/040212084949.htm
Journal Of The American Medical Association. "'Dry Eye' In Women May Be Linked To Sex Hormones." ScienceDaily. www.sciencedaily.com/releases/2004/02/040212084949.htm (accessed August 22, 2014).

Share This




More Health & Medicine News

Friday, August 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Newsy (Aug. 21, 2014) An experimental drug used to treat Marburg virus in rhesus monkeys could give new insight into a similar treatment for Ebola. Video provided by Newsy
Powered by NewsLook.com
Two US Ebola Patients Leave Hospital Free of the Disease

Two US Ebola Patients Leave Hospital Free of the Disease

AFP (Aug. 21, 2014) Two American missionaries who were sickened with Ebola while working in Liberia and were treated with an experimental drug are doing better and have left the hospital, doctors say on August 21, 2014. Duration: 01:05 Video provided by AFP
Powered by NewsLook.com
Cadavers, a Teen, and a Medical School Dream

Cadavers, a Teen, and a Medical School Dream

AP (Aug. 21, 2014) Contains graphic content. He's only 17. But Johntrell Bowles has wanted to be a doctor from a young age, despite the odds against him. He was recently the youngest participant in a cadaver program at the Indiana University NW medical school. (Aug. 21) Video provided by AP
Powered by NewsLook.com
American Ebola Patients Released: What Cured Them?

American Ebola Patients Released: What Cured Them?

Newsy (Aug. 21, 2014) It's unclear whether the American Ebola patients' recoveries can be attributed to an experimental drug or early detection and good medical care. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins