Featured Research

from universities, journals, and other organizations

Invisible Light And Special Goggles May Improve Brain Tumor Surgery

Date:
March 29, 2004
Source:
University Of Texas M. D. Anderson Cancer Center
Summary:
Some day "night vision" goggles and beams of near infrared light may be able to detect tiny tumors and areas of cancerous tissue in the brain that surgeons can't normally see, say investigators at The University of Texas M. D. Anderson Cancer.

ORLANDO -- Some day "night vision" goggles and beams of near infrared light may be able to detect tiny tumors and areas of cancerous tissue in the brain that surgeons can't normally see, say investigators at The University of Texas M. D. Anderson Cancer.

Related Articles


They say their advance, successfully tested in animals, is designed to help neurosurgeons define tumor "margins" -- the area where a tumor ends and normal tissue begins -- when they operate on patients with brain tumors.

"No one can determine tumor margins in brain tissue adequately right now, but our hope is that the emerging technology of near-infrared fluorescence optical imaging will provide this crucial information in real time to surgeons, as an operation is under way," says investigator Shi Ke, M.D., an instructor in the Department of Experimental Diagnostic Imaging at M. D. Anderson.

Ke is presenting results of an imaging probe that allowed detection of small tumors in the brain at the annual meeting of the American Association for Cancer Research.

When perfected, near infrared optical imaging of brain tumors may offer a "safe, non-invasive and highly sensitive" method that can improve surgical treatment, says Ke.

Although neurosurgeons now use diagnostic scans that pinpoint where tumors are prior to an operation, once the skull is open, soft brain matter shifts, making it difficult to know where tumor tissue ends.

Life expectancy of brain tumor patients is tied to the amount of tumor that remains, according to Ke, Research reported recently by neurosurgeons at M. D. Anderson found that if 98 percent of a glioma brain tumor is removed, patients survive for more than a year. If 95 percent of the tumor is removed, survival decreases by more than four months.

Although several research teams around the country have been experimenting with similar devices, collectively known as near-infrared (NIR) optical imaging, no one has tried it before in brain tumors, says Ke.

To make it work for brain tumors, Ke and others in a research team lead by Chun Li, M.D., associate professor in the Department of Experimental Diagnostic Imaging, developed a special kind of dye that can find its way to tumors inoculated in the brain. They chose a dye found from an in vivo screening process that binds to many human tumors as well as in gliomas, but not to normal tissue. Then, using a NIR camera developed by scientists at Texas A & M University, they tested the ability of the dye to pick up tumors as they grew in laboratory mice.

Light in the near-infrared wavelength spectrum easily penetrated the skulls of the animals to "excite" the dye, and the emitted fluorescent signal was then captured by a CCD camera. The tumors shone with a brighter light than the normal brain tissue around them, says Ke.

The study is an important proof-of-principle that such a device can detect brain tumor margins and small tumors, he says. Now, investigators are testing NIR optical imaging in the earliest stages of brain tumor development, and they also plan to test its ability to distinguish melanoma, endometrial and prostate tumors.


Story Source:

The above story is based on materials provided by University Of Texas M. D. Anderson Cancer Center. Note: Materials may be edited for content and length.


Cite This Page:

University Of Texas M. D. Anderson Cancer Center. "Invisible Light And Special Goggles May Improve Brain Tumor Surgery." ScienceDaily. ScienceDaily, 29 March 2004. <www.sciencedaily.com/releases/2004/03/040329075404.htm>.
University Of Texas M. D. Anderson Cancer Center. (2004, March 29). Invisible Light And Special Goggles May Improve Brain Tumor Surgery. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2004/03/040329075404.htm
University Of Texas M. D. Anderson Cancer Center. "Invisible Light And Special Goggles May Improve Brain Tumor Surgery." ScienceDaily. www.sciencedaily.com/releases/2004/03/040329075404.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins