Featured Research

from universities, journals, and other organizations

Stem Cell Discovery Could Aid In Diabetes Treatments

Date:
August 27, 2004
Source:
University Of Alberta
Summary:
A University of Alberta diabetes researcher has helped uncover a possible new source of insulin for diabetics and a valuable clue in the treatment of neurological disorders.

August 23, 2004 – A University of Alberta diabetes researcher has helped uncover a possible new source of insulin for diabetics and a valuable clue in the treatment of neurological disorders.

Dr. Greg Korbutt, a member of the U of A research team that developed the Edmonton Protocol treatment for type 1 diabetes, was part of a research collaboration centred at the University of Toronto that discovered pancreatic stem cells in mice. The finding is important because researchers were able to produce both neurons and insulin-producing cells from the stem cells found in the pancreas.

The discovery could have an enormous impact on the treatment of diabetes. The Edmonton Protocol developed at the U of A aids patients suffering severe forms of type 1 diabetes with transplants of pancreatic islet cells, which produce insulin and free the patients of the need for insulin injections.

"One of our limitations [with the Edmonton Protocol] is the amount of human donor organs that are available for recipients," said Korbutt, who became involved in the research project through the national Stem Cell Network, which funded the project with the Canadian Institutes of Health Research.

The discovery, reported in the current edition of the journal Nature Biotechnology, "could be a potential way of overcoming the supply problem," said Korbutt, adding that he thinks it is "very likely" that pancreatic stem cells will be found in humans.

Researchers could come up with a way of making insulin-producing cells and implanting them in diabetic patients, or they could figure out a way to kick-start the stem cells within the patients so the patients begin producing insulin on their own again.

More than two million Canadian have diabetes. Nationwide, it is responsible for more than 40,000 deaths every year.

The researchers also managed to coax the stem cells into producing neurons, the substance of the central nervous system. Korbutt says that finding is "scientifically a very interesting observation." The finding raises the possibility of developing new treatments for neurological disorders. Patients with Parkinson's Disease, for example, might be helped if the stem cells can manufacture cells that produce L-Dopamine.

Korbutt, a professor and director of the human islet quality control laboratory in the U of A Department of Surgery, said he's impressed with the project, headed up by doctoral students Simon Smukler and Raewyn Seaberg, who are working with Dr. Derek van der Kooy. "It's a great collaboration," he said.


Story Source:

The above story is based on materials provided by University Of Alberta. Note: Materials may be edited for content and length.


Cite This Page:

University Of Alberta. "Stem Cell Discovery Could Aid In Diabetes Treatments." ScienceDaily. ScienceDaily, 27 August 2004. <www.sciencedaily.com/releases/2004/08/040826084001.htm>.
University Of Alberta. (2004, August 27). Stem Cell Discovery Could Aid In Diabetes Treatments. ScienceDaily. Retrieved September 20, 2014 from www.sciencedaily.com/releases/2004/08/040826084001.htm
University Of Alberta. "Stem Cell Discovery Could Aid In Diabetes Treatments." ScienceDaily. www.sciencedaily.com/releases/2004/08/040826084001.htm (accessed September 20, 2014).

Share This



More Health & Medicine News

Saturday, September 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins