Featured Research

from universities, journals, and other organizations

Some Anti-Psychotic Medications May Trigger Diabetes

Date:
October 8, 2004
Source:
Yale University
Summary:
The rate of diabetes among persons taking certain newer anti-psychotic medications is higher than that found in the general population, Yale researchers report in a study in the American Journal of Psychiatry.

New Haven, Conn. -- The rate of diabetes among persons taking certain newer anti-psychotic medications is higher than that found in the general population, Yale researchers report in a study in the American Journal of Psychiatry.

Related Articles


The study followed patients with schizophrenia and no history of diabetes who used four of six new atypical medications or conventional anti-psychotic medications. The atypical medications - clozapine, risperidone, olanzapine, quetiapine - are considered to cause fewer severe side effects. Two atypical medications were not included because they had just been approved at the time the study began.

Of the 56,849 patients in the sample, 7.3 percent of patients were diagnosed with diabetes mellitus during the one- to two-year follow up period, corresponding to an annual incidence rate of 4.4 percent. The rate was higher for patients taking clozapine and olanzapine.

"The rate is five to 10 times higher than the estimated rate of 6.3 cases per 1,000 in the general U.S. population," said Douglas Leslie, first author of the paper and assistant professor of psychiatry and epidemiology and public health.

Leslie and co-author Robert Rosenheck, M.D., professor of psychiatry and epidemiology and public health, said it is not known what causes the diabetes, but one possibility is weight gain associated with taking the medications. Other factors might be the mental illness itself, poorer overall physical health, unhealthy lifestyles, or less access to health care services, he said.

The study also found that only 0.2 percent of the patients were hospitalized for ketoacidosis -- which is an accumulation of ketone bodies associated with uncontrolled diabetes and is potentially life threatening.

Since they began their research, the U.S. Food and Drug Administration ordered all manufacturers of these drugs to include a warning on related medication labels about diabetes as a possible side effect.

Citation: American Journal of Psychiatry, Vol. 161: pp 1709-1711 (September, 2004)


Story Source:

The above story is based on materials provided by Yale University. Note: Materials may be edited for content and length.


Cite This Page:

Yale University. "Some Anti-Psychotic Medications May Trigger Diabetes." ScienceDaily. ScienceDaily, 8 October 2004. <www.sciencedaily.com/releases/2004/10/041008030605.htm>.
Yale University. (2004, October 8). Some Anti-Psychotic Medications May Trigger Diabetes. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2004/10/041008030605.htm
Yale University. "Some Anti-Psychotic Medications May Trigger Diabetes." ScienceDaily. www.sciencedaily.com/releases/2004/10/041008030605.htm (accessed November 26, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, November 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com
Madagascar Working to Contain Plague Outbreak

Madagascar Working to Contain Plague Outbreak

AFP (Nov. 24, 2014) Madagascar said Monday it is trying to contain an outbreak of plague -- similar to the Black Death that swept Medieval Europe -- that has killed 40 people and is spreading to the capital Antananarivo. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins