Featured Research

from universities, journals, and other organizations

Hormone Therapy For Prostate Cancer Can Affect Men's Thinking

Date:
March 15, 2005
Source:
John Wiley & Sons, Inc.
Summary:
A new study finds men treated with hormone therapy for prostate cancer may experience temporary cognitive changes that can affect verbal fluency, visual recognition and visual memory.

A new study finds men treated with hormone therapy for prostate cancer may experience temporary cognitive changes that can affect verbal fluency, visual recognition and visual memory. The study, published in the April 1, 2005 issue of CANCER (http://www.interscience.wiley.com/cancer-newsroom), a peer-reviewed journal of the American Cancer Society, finds the degree of cognitive dysfunction appeared to be related to a decline in serum estradiol brought on by hormonal treatment.

Related Articles


Androgen-deprivation therapy (AD) is an effective adjuvant therapy in the treatment of prostate cancer. It effectively reduces levels of testosterone, which acts as a tumor stimulant, and estradiol, a form of estrogen in men. Testosterone and estradiol are known to be important in neurological development and play a particularly important role in the cognitive areas of learning and memory. Previous studies in women have shown declining estradiol levels to effect cognition but until now little data existed in men.

Eeva Salminen, M.D. and colleagues at Turku University Hospital in Turku, Finland investigated the relationship between serum estradiol and cognitive functioning in men with prostate cancer treated with androgen-deprivation therapy.

They found cognitive performance in several specific areas were associated with declines in estradiol brought on by the therapy. Six months into treatment, men were found to have temporary, marginal but significant declines in visual memory of figures and recognition speed of numbers. Tests at twelve months showed marginal improvement in verbal fluency associated with estradiol declines. No other cognitive areas were affected. The degree of cognitive change was related to the magnitude of estradiol declines.

Despite these "selective and marginal" changes associated with estradiol declines, "cognitive function appears to be well preserved during 12 months AD in men without previous neurological or psychological diseases."

###

Article: "Estradiol and Cognition during Androgen Deprivation in Men with Prostate Carcinoma," E.K. Salminen, R.I. Portin, A. Koskinen, H. Helenius, and M. Nurmi, CANCER; Published Online: February 28, 2005 (DOI: 10.1002/cncr.20962); Print Issue Date: April 1, 2005.


Story Source:

The above story is based on materials provided by John Wiley & Sons, Inc.. Note: Materials may be edited for content and length.


Cite This Page:

John Wiley & Sons, Inc.. "Hormone Therapy For Prostate Cancer Can Affect Men's Thinking." ScienceDaily. ScienceDaily, 15 March 2005. <www.sciencedaily.com/releases/2005/03/050308093027.htm>.
John Wiley & Sons, Inc.. (2005, March 15). Hormone Therapy For Prostate Cancer Can Affect Men's Thinking. ScienceDaily. Retrieved November 24, 2014 from www.sciencedaily.com/releases/2005/03/050308093027.htm
John Wiley & Sons, Inc.. "Hormone Therapy For Prostate Cancer Can Affect Men's Thinking." ScienceDaily. www.sciencedaily.com/releases/2005/03/050308093027.htm (accessed November 24, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, November 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com
Winter Can Cause Depression — Here's How To Combat It

Winter Can Cause Depression — Here's How To Combat It

Newsy (Nov. 23, 2014) Millions of American suffer from seasonal depression every year. It can lead to adverse health effects, but there are ways to ease symptoms. Video provided by Newsy
Powered by NewsLook.com
Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins