Featured Research

from universities, journals, and other organizations

Radiofrequency Ablation Is Effective Long-term Treatment For Kidney Tumors

Date:
June 22, 2005
Source:
Massachusetts General Hospital
Summary:
Massachusetts General Hospital researchers have shown that radiofrequency ablation -- a minimally invasive way of destroying tissue -- is an effective, longlasting treatment for small kidney tumors in selected patients.

Massachusetts General Hospital (MGH) researchers have shown that radiofrequency ablation (RFA) -- a minimally invasive way of destroying tissue -- is an effective, longlasting treatment for small kidney tumors in selected patients. In a followup to research published in 2003, the investigators found that RFA treatment of renal cell carcinoma, the most common kidney cancer, continued to be successful 4 to 6 years after administration. The report appears in the July issue of the Journal of Urology.

"This study shows, for the first time, that this is a very effective long-term treatment," says W. Scott McDougal, MD, chief of Urology at MGH and lead author of the study. Renal cell carcinoma will be diagnosed in almost 32,000 Americans this year and is most frequently treated with surgical removal through either an open or laparoscopic procedure.

RFA delivers heat generated by electrical energy to sites within the body through a thin needle, similar to probes used in biopsy procedures. Placement of the probe is guided by CT scan, ultrasound or other imaging techniques. Widely used to treat cardiac arrhythmias, RFA is also being investigated for destruction of small liver tumors and has been used for more than ten years to treat a benign bone tumor called osteoid osteoma.

For more than six years MGH physicians have been using RFA to treat kidney tumors in patients for whom surgical removal was not an option because of other health concerns. For the current study, the research team reviewed information on 16 of the first patients treated with the technique; three patients had multiple tumors, making a total of 20 tumors treated.

In the four years following their treatment, five patients whose treatment was initially successful died from causes unrelated to kidney cancer. Of the 11 remaining patients, none had any recurrence or metastasis of the kidney tumor 4 to 6 years after treatment. Overall, treatment of all tumors on the surface of the kidney was successful, as was the treatment of tumors deep within the kidney, which sometimes requires additional treatments. Two patients had what are called mixed tumors, and only one of them was treated successfully. Although treatment of the other mixed-tumor patient did not reduce the size of the lesion, that patient died of an unrelated brain tumor a year after treatment.

McDougal adds that the MGH team now has used RFA to treat a total of 100 renal cell carcinomas in 85 patients with similar results -- successful tumor destruction in 100 percent of surface tumors and 78 percent of central tumors. "Right now, older patients with small lesions in limited areas of their kidneys are good candidates for this procedure. We need to wait for 10-year followup information to determine whether it will be appropriate for patients with a longer life expectancy." McDougal is the Walter S. Kerr, Jr. Professor of Urology at Harvard Medical School.

The report's co-authors are Francis McGovern, MD, MGH Urology, and Debra Gervais, MD, and Peter R. Mueller, MD, of the MGH Department of Radiology.

###

Massachusetts General Hospital, established in 1811, is the original and largest teaching hospital of Harvard Medical School. The MGH conducts the largest hospital-based research program in the United States, with an annual research budget of more than $450 million and major research centers in AIDS, cardiovascular research, cancer, cutaneous biology, medical imaging, neurodegenerative disorders, transplantation biology and photomedicine. In 1994, MGH and Brigham and Women's Hospital joined to form Partners HealthCare System, an integrated health care delivery system comprising the two academic medical centers, specialty and community hospitals, a network of physician groups, and nonacute and home health services.


Story Source:

The above story is based on materials provided by Massachusetts General Hospital. Note: Materials may be edited for content and length.


Cite This Page:

Massachusetts General Hospital. "Radiofrequency Ablation Is Effective Long-term Treatment For Kidney Tumors." ScienceDaily. ScienceDaily, 22 June 2005. <www.sciencedaily.com/releases/2005/06/050621095300.htm>.
Massachusetts General Hospital. (2005, June 22). Radiofrequency Ablation Is Effective Long-term Treatment For Kidney Tumors. ScienceDaily. Retrieved April 17, 2014 from www.sciencedaily.com/releases/2005/06/050621095300.htm
Massachusetts General Hospital. "Radiofrequency Ablation Is Effective Long-term Treatment For Kidney Tumors." ScienceDaily. www.sciencedaily.com/releases/2005/06/050621095300.htm (accessed April 17, 2014).

Share This



More Health & Medicine News

Thursday, April 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com
Thousands Of Vials Of SARS Virus Go Missing

Thousands Of Vials Of SARS Virus Go Missing

Newsy (Apr. 16, 2014) A research institute in Paris somehow misplaced more than 2,000 vials of the deadly SARS virus. Video provided by Newsy
Powered by NewsLook.com
Formerly Conjoined Twins Released From Dallas Hospital

Formerly Conjoined Twins Released From Dallas Hospital

Newsy (Apr. 16, 2014) Conjoined twins Emmett and Owen Ezell were separated by doctors in August. Now, nearly nine months later, they're being released from the hospital. Video provided by Newsy
Powered by NewsLook.com
Ebola Outbreak Now Linked To 121 Deaths

Ebola Outbreak Now Linked To 121 Deaths

Newsy (Apr. 15, 2014) The ebola virus outbreak in West Africa is now linked to 121 deaths. Health officials fear the virus will continue to spread in urban areas. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins