Featured Research

from universities, journals, and other organizations

Nicotine Helps Schizophrenics With Attention And Memory

Date:
July 11, 2005
Source:
Yale University
Summary:
Cigarette smoking may improve attention and short--term memory in persons with schizophrenia by stimulating nicotine receptors in the brain, according to a study by Yale School of Medicine researchers in the June issue of The Archives of General Psychiatry.

New Haven, Conn. -- Cigarette smoking may improve attention and short--term memory in persons with schizophrenia by stimulating nicotine receptors in the brain, according to a study by Yale School of Medicine researchers in the June issue of The Archives of General Psychiatry.

Persons with schizophrenia smoke two to three times more than smokers without mental illness, said the researchers. They found that when study subjects with schizophrenia stopped smoking, attention and short--term memory were more impaired, but, when they started smoking again, their cognitive function improved. No effects from stopping or resuming smoking were observed in smokers without mental illness.

Participants with and without schizophrenia were then asked to smoke while taking a drug called mecamylamine, which blocks nicotinic acetylcholine receptors in the brain, preventing the nicotine from acting on those receptors. Mecamylamine blocked the ability of smoking to improve cognitive deficits in schizophrenia, but not in persons without mental illness. The findings suggest that when people with schizophrenia smoke, they may in part be self--medicating with nicotine to remedy cognitive deficits.

"Our findings have significant implications for developing treatments for cognitive deficits and nicotine addiction in schizophrenia," said Kristi Sacco, associate research scientist in the Department of Psychiatry and first author of the study. She said the results may also help explain the high rates of smoking in people with schizophrenia. She added that this study does not suggest that people with schizophrenia who do not smoke should start smoking.

Tony George, M.D., associate professor in the Department of Psychiatry, is senior author of the study.

The study was funded by grants from The National Institute on Drug Abuse and the National Alliance for Research on Schizophrenia and Depression. The researchers are members of the Transdisciplinary Tobacco Use Research Center at Yale and the Program for Research in Smokers with Mental Illness. For more information about both projects please see www.quitwithyale.org and www.prism.yale.edu.


Story Source:

The above story is based on materials provided by Yale University. Note: Materials may be edited for content and length.


Cite This Page:

Yale University. "Nicotine Helps Schizophrenics With Attention And Memory." ScienceDaily. ScienceDaily, 11 July 2005. <www.sciencedaily.com/releases/2005/07/050710202418.htm>.
Yale University. (2005, July 11). Nicotine Helps Schizophrenics With Attention And Memory. ScienceDaily. Retrieved September 3, 2014 from www.sciencedaily.com/releases/2005/07/050710202418.htm
Yale University. "Nicotine Helps Schizophrenics With Attention And Memory." ScienceDaily. www.sciencedaily.com/releases/2005/07/050710202418.htm (accessed September 3, 2014).

Share This



More Mind & Brain News

Wednesday, September 3, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Can You Train Your Brain To Eat Healthy?

Can You Train Your Brain To Eat Healthy?

Newsy (Sep. 1, 2014) New research says if you condition yourself to eat healthy foods, eventually you'll crave them instead of junk food. Video provided by Newsy
Powered by NewsLook.com
Coffee Then Napping: The (New) Key To Alertness

Coffee Then Napping: The (New) Key To Alertness

Newsy (Aug. 30, 2014) Researchers say having a cup of coffee then taking a nap is more effective than a nap or coffee alone. Video provided by Newsy
Powered by NewsLook.com
Young Entrepreneurs Get $100,000, If They Quit School

Young Entrepreneurs Get $100,000, If They Quit School

AFP (Aug. 29, 2014) Twenty college-age students are getting 100,000 dollars from a Silicon Valley leader and a chance to live in San Francisco in order to work on the start-up project of their dreams, but they have to quit school first. Duration: 02:20 Video provided by AFP
Powered by NewsLook.com
Baby Babbling Might Lead To Faster Language Development

Baby Babbling Might Lead To Faster Language Development

Newsy (Aug. 29, 2014) A new study suggests babies develop language skills more quickly if their parents imitate the babies' sounds and expressions and talk to them often. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins