Featured Research

from universities, journals, and other organizations

Nicotine Helps Schizophrenics With Attention And Memory

Date:
July 11, 2005
Source:
Yale University
Summary:
Cigarette smoking may improve attention and short--term memory in persons with schizophrenia by stimulating nicotine receptors in the brain, according to a study by Yale School of Medicine researchers in the June issue of The Archives of General Psychiatry.

New Haven, Conn. -- Cigarette smoking may improve attention and short--term memory in persons with schizophrenia by stimulating nicotine receptors in the brain, according to a study by Yale School of Medicine researchers in the June issue of The Archives of General Psychiatry.

Persons with schizophrenia smoke two to three times more than smokers without mental illness, said the researchers. They found that when study subjects with schizophrenia stopped smoking, attention and short--term memory were more impaired, but, when they started smoking again, their cognitive function improved. No effects from stopping or resuming smoking were observed in smokers without mental illness.

Participants with and without schizophrenia were then asked to smoke while taking a drug called mecamylamine, which blocks nicotinic acetylcholine receptors in the brain, preventing the nicotine from acting on those receptors. Mecamylamine blocked the ability of smoking to improve cognitive deficits in schizophrenia, but not in persons without mental illness. The findings suggest that when people with schizophrenia smoke, they may in part be self--medicating with nicotine to remedy cognitive deficits.

"Our findings have significant implications for developing treatments for cognitive deficits and nicotine addiction in schizophrenia," said Kristi Sacco, associate research scientist in the Department of Psychiatry and first author of the study. She said the results may also help explain the high rates of smoking in people with schizophrenia. She added that this study does not suggest that people with schizophrenia who do not smoke should start smoking.

Tony George, M.D., associate professor in the Department of Psychiatry, is senior author of the study.

The study was funded by grants from The National Institute on Drug Abuse and the National Alliance for Research on Schizophrenia and Depression. The researchers are members of the Transdisciplinary Tobacco Use Research Center at Yale and the Program for Research in Smokers with Mental Illness. For more information about both projects please see www.quitwithyale.org and www.prism.yale.edu.


Story Source:

The above story is based on materials provided by Yale University. Note: Materials may be edited for content and length.


Cite This Page:

Yale University. "Nicotine Helps Schizophrenics With Attention And Memory." ScienceDaily. ScienceDaily, 11 July 2005. <www.sciencedaily.com/releases/2005/07/050710202418.htm>.
Yale University. (2005, July 11). Nicotine Helps Schizophrenics With Attention And Memory. ScienceDaily. Retrieved August 2, 2014 from www.sciencedaily.com/releases/2005/07/050710202418.htm
Yale University. "Nicotine Helps Schizophrenics With Attention And Memory." ScienceDaily. www.sciencedaily.com/releases/2005/07/050710202418.htm (accessed August 2, 2014).

Share This




More Mind & Brain News

Saturday, August 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Work Can Be Stressful, But Is Unemployment Worse?

Work Can Be Stressful, But Is Unemployment Worse?

Newsy (Aug. 1, 2014) A new study shows stress at work can be hard on your health, but people who are unemployed might be at even greater risk of health problems. Video provided by Newsy
Powered by NewsLook.com
Google (Kind Of) Complies With 'Right To Be Forgotten Law'

Google (Kind Of) Complies With 'Right To Be Forgotten Law'

Newsy (July 31, 2014) Google says it is following Europe's new "Right To Be Forgotten Law," which eliminates user information upon request, but only to a certain degree. Video provided by Newsy
Powered by NewsLook.com
Stroke Signs: Three Hour Deadline

Stroke Signs: Three Hour Deadline

Ivanhoe (July 31, 2014) Sometimes the signs of a stroke are far from easy to recognize. Learn from one young father’s story on the signs of a stroke. Video provided by Ivanhoe
Powered by NewsLook.com
Grain Brain May Be Harming Us

Grain Brain May Be Harming Us

Ivanhoe (July 31, 2014) Could eating carbohydrates be harmful to our brain health? Find out what one neurologist says about changing our diets. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins