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Most Embryos Produced During IVF Do Not Result In Live Births

Date:
September 12, 2005
Source:
Yale University
Summary:
Researchers at Yale School of Medicine have found that 85 percent of embryos transferred during in vitro fertilization fail to become live births, highlighting the need for improving diagnostic techniques to identify viable embryos.
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New Haven, Conn. -- Researchers at Yale School of Medicine have foundthat 85 percent of embryos transferred during in vitro fertilizationfail to become live births, highlighting the need for improvingdiagnostic techniques to identify viable embryos.

Published in the August issue of Fertility and Sterility, the studyreviewed seven years of U.S. statistics from all the fertility clinicsthat report data on reproductive techniques. Director of the YaleFertility Center, Pasquale Patrizio, M.D., professor in the Departmentof Obstetrics, Gynecology & Reproductive Sciences led the project.

"Something in nature has decided that these implanted embryosare not viable," said Patrizio, who conducted the study with co-authorGeorge Kovalevsky, M.D.

"We as practitioners in the reproductive clinic are in aparadoxical situation," Patrizio added. "There is pressure to reducemultiple births, but we need to do so knowing that the majority of theembryos that are transferred do not implant. It is difficult to strikea balance between these two needs."

Patrizio said he and his fellow physicians strive to betteridentify the embryos with the most potential. But addressing thegrowing pressure to transfer fewer embryos to reduce multiple births isa difficult task unless they can come up with a method in the lab toidentify the best embryos.

"Some potential methods for screening embryos include usingpre-implantation genetic diagnosis and biochemical markers of embryoviability," said Patrizio. "In addition this study should also move thefield toward perfecting methods of egg production."

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Citation: Fertility and Sterility, Vol. 84, No. 2, 325-530 (August 2005).


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The above post is reprinted from materials provided by Yale University. Note: Materials may be edited for content and length.


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Yale University. "Most Embryos Produced During IVF Do Not Result In Live Births." ScienceDaily. ScienceDaily, 12 September 2005. <www.sciencedaily.com/releases/2005/09/050912124150.htm>.
Yale University. (2005, September 12). Most Embryos Produced During IVF Do Not Result In Live Births. ScienceDaily. Retrieved July 29, 2015 from www.sciencedaily.com/releases/2005/09/050912124150.htm
Yale University. "Most Embryos Produced During IVF Do Not Result In Live Births." ScienceDaily. www.sciencedaily.com/releases/2005/09/050912124150.htm (accessed July 29, 2015).

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