Featured Research

from universities, journals, and other organizations

Childhood Cancer Survivors Are More Likely To Go Through Early Menopause

Date:
July 5, 2006
Source:
Journal of the National Cancer Institute
Summary:
Women who survive childhood cancer are more likely to suffer premature menopause, according to a study in the July 5 issue of the Journal of the National Cancer Institute. Risk factors include radiation to the ovaries and certain forms of chemotherapy.

Women who survive childhood cancer are more likely to suffer premature menopause, according to a study in the July 5 issue of the Journal of the National Cancer Institute. Risk factors include radiation to the ovaries and certain forms of chemotherapy.

Over 70% of children or adolescents diagnosed with cancer will survive long-term. Survivors have an increased risk of premature menopause, defined as menopause before age 40.

Charles A. Sklar, M.D., of Memorial Sloan-Kettering Cancer Center in New York, and colleagues examined the incidence of and risk factors for premature menopause in 2,819 childhood cancer survivors over age 18 as identified in the Childhood Cancer Survivor Study and 1,065 female siblings of survivors.

The authors observed that premature menopause occurred in 126 childhood cancer survivors and 33 siblings. Non-surgical premature menopause occurred more frequently in childhood cancer survivors. For cancer patients treated with both abdominal-pelvic radiation and the class of chemotherapy known as alkylating drugs, the cumulative incidence of premature menopause was nearly 30%. Age, radiation to the ovaries, a diagnosis of Hodgkin lymphoma, and treatment with alkylating chemotherapy increased a cancer survivor's risk of premature menopause.

The authors write, "The results of this study will facilitate counseling current survivors about their future risk of premature menopause and will aid in designing new regimens that seek to diminish late ovarian toxicity."

In an accompanying editorial, Wendy Y. Chen, M.D., and JoAnn E. Manson, M.D., Dr.P.H., from Brigham and Women's Hospital in Boston, discuss the health effects of premature menopause. They write, "The current study helps clinicians to identify women at increased risk of [premature menopause], so that prevention, screening, and treatment strategies can be implemented at an earlier stage."


Story Source:

The above story is based on materials provided by Journal of the National Cancer Institute. Note: Materials may be edited for content and length.


Cite This Page:

Journal of the National Cancer Institute. "Childhood Cancer Survivors Are More Likely To Go Through Early Menopause." ScienceDaily. ScienceDaily, 5 July 2006. <www.sciencedaily.com/releases/2006/07/060705090857.htm>.
Journal of the National Cancer Institute. (2006, July 5). Childhood Cancer Survivors Are More Likely To Go Through Early Menopause. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2006/07/060705090857.htm
Journal of the National Cancer Institute. "Childhood Cancer Survivors Are More Likely To Go Through Early Menopause." ScienceDaily. www.sciencedaily.com/releases/2006/07/060705090857.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins