Ovarian Cancer News
September 2, 2015

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September 2, 2015

Anti-Inflammatory Drug Acts Against Ovarian Cancer, Scientists Find

July 28, 2015 — A non-steroidal anti-inflammatory drug (NSAID) called ketorolac helped women with ovarian cancer to survive longer, researchers report. Ketorolac, marketed as Toradol®, is approved for clinical use ... read more

Cancer Drug 49 Times More Potent Than Cisplatin

July 7, 2015 — A new cancer drug has been found to have effectiveness for ovarian and bowel cancer that is 49 times as potent is Cisplatin. The key to this new drug, researchers report, is that it can shut down a ... read more

Body Mass Index Impacts Ovarian Cancer Chemotherapy Dosages

July 2, 2015 — Ovarian cancer patients who are overweight or obese are often given less chemotherapy per pound of body weight in order to reduce the toxic side effects associated with higher doses, and this in turn ... read more

Experimental Drug Combined With Standard Chemo May Shrink Treatment-Resistant Ovarian Cancers, Animal Study Shows

July 1, 2015 — Working in cell cultures and mice, researchers have found that an experimental drug called fostamatinib combined with the chemotherapy drug paclitaxel may overcome ovarian cancer cells' ... read more

Parkinson's Disease Appears Associated With Many Cancers in Taiwan

June 18, 2015 — Parkinson's disease appeared associated with 16 types of cancer in a study in Taiwan, an effort to explain the association in an East Asian population because most prior research has been ... read more

Scientists Find Genetic Variants Key to Understanding Origins of Ovarian Cancer

June 15, 2015 — New research is bringing the origins of ovarian cancer into sharper focus.The study highlights the discovery of three genetic variants associated with mucinous ovarian carcinomas (MOCs), offering the ... read more

June 11, 2015 — Ovarian cancer shuts down immune system cells that would otherwise act as a first line of defense against the deadly tumor, scientists report. But a therapy that restores the cells' ... read more

ADAMTS Family of Genes May Be the Next 'Thing' in Ovarian Cancer Treatment

June 11, 2015 — There is the Addams Family. And then there is the ADAMTS family. While one is mindless entertainment, the latter may prove to be a new genetic avenue for designing ovarian cancer treatment, ... read more

Gene Mutations Sensitize Tumors to Specific Cancer Drugs, Study Shows

June 11, 2015 — Mutations in ARID1a, which are common in many cancer types, disrupt DNA damage repair in cancer cells, allowing the cancer to progress, scientists report. This gene may also be an Achilles' heel ... read more

Theranostic PET Takes on Both Ovarian and Prostate Cancer

June 8, 2015 — A first-in-human study shows how a powerful new drug finds and attaches itself to the ovarian and prostate cancer cells for both imaging and personalized cancer ... read more

Rewriting the Book on Chemo-Resistant Cancers With a DNA Library

May 29, 2015 — Researcher are finding out why ovarian cancer is resistant to certain types of chemo and hope to eventually identify a different drug ... read more

Study Could Explain Why Ovarian Cancer Treatments Fail

May 27, 2015 — Ovarian cancer cells can lock into survival mode and avoid being destroyed by chemotherapy, an international study reports. The research used whole genome sequencing to analyse tumor DNA samples from ... read more

Ovarian Cancer-Specific Markers Set the Stage for Early Diagnosis, Personalized Treatments

May 25, 2015 — Six mRNA isoforms (bits of genetic material) produced by ovarian cancer cells but not normal cells have been identified by scientists, opening up the possibility that they could be used to diagnose ... read more

International Study of Advanced Prostate Cancer Genome Finds Potential Targets for Drug Therapy

May 21, 2015 — First study of the genomic composition of prostate cancer shows many patients have gene mutations that can be targeted with existing or potential drugs. The finding is based on an analysis of tumor ... read more

Researchers Discover Molecular Approach to Promote Cancer Cell Death

May 21, 2015 — Lung cancer researchers have discovered a novel strategy to exploit apoptosis, a form of programmed cell death, for the treatment of lung cancer. The protein Bcl-2 is a known target for cancer ... read more

Biomarker May Boost Ovarian Cancer Chemotherapy Response

May 20, 2015 — A molecule that helps control gene expression may play a role in controlling chemotherapy resistance among patients with the most common form of ovarian cancer. Chemoresistance is a major challenge ... read more

Chemo Before Surgery Benefits Patients With Advanced Ovarian Cancer

May 19, 2015 — Women with advanced ovarian cancer have fewer side effects and tend to have a better quality of life if given chemotherapy before surgery, according to a study. Delaying surgery also reduced the ... read more

Scientists Discover New Molecules That Kill Cancer Cells and Protect Healthy Cells

May 13, 2015 — Molecules could treat cervical, breast, ovarian, and lung cancers, new research in mice suggests. Scientists have found a new family of molecules that kill cancer cells and protect healthy cells, ... read more

May 6, 2015 — A long-standing mystery about the origin of one of the cell types that make up the ovary has been solved by researchers. The team also discovered how ovarian cells share information during ... read more

New Screening Technique Could Pick Up Twice as Many Women With Ovarian Cancer

May 4, 2015 — A new screening method can detect twice as many women with ovarian cancer as conventional strategies, according to the latest results from the largest trial of its kind. The new method detected ... read more

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