Featured Research

from universities, journals, and other organizations

Neurosurgical Treatment Of Anxiety Disorders Effective -- But Risky

Date:
July 19, 2006
Source:
Karolinska Institutet
Summary:
Severely ill patients with anxiety disorders or Obsessive-Compulsive Disorder undergoing neurosurgical treatment risk serious complications. The safety of the method must be carefully reconsidered. This according to the largest study made to date on the long-term effects of this surgical method.

Severely ill patients with anxiety disorders or Obsessive-Compulsive Disorder undergoing neurosurgical treatment risk serious complications. The safety of the method must be carefully reconsidered. This according to the largest study made to date on the long-term effects of this surgical method.

"The frequency of adverse effects was higher than expected. Neurosurgery for mental disorders is currently gaining a lot of attention in the professional community with new ongoing trials in several countries and I think our results are another reason for caution", says psychiatrist Christian Rück at Karolinska Institutet in Sweden.

Fifty-one patients with either severe and chronic obsessive-compulsive disorder or other and anxiety disorders have been monitored for up to 23 years following capsulotomy, a neurosurgical operation which involves severing nerve fibres in the central part of the brain.

"Capsulotomy is an effective method for relieving anxiety and obsessions, and its effects remain many years after the operation," says Christian Rück, who has been carefully following up recipients of this treatment. "Many seriously troubled patients feel that the operation saved their lives. There is, however, a serious risk of side-effects."

The results of the study are to be presented in a forthcoming doctoral thesis at Karolinska Institutet. The effects of the operation were measured using questionnaires and thorough interviews with patients and their relatives. The follow-up also included neuropsychological examination and MRI examination of the brain.

One important finding is that the side-effects of the operation are more common than previously thought. Just over a third of the patients displayed signs of apathy and difficulties planning and executing activities. Some patients had developed epilepsy, disinhibition or urinary incontinence.

"There is clearly an unacceptably large risk of adverse reactions to the surgical methods that have been applied to date," says Dr Rück. "The first course of action for patients who don't respond to normal psychiatric treatment should be to use new, non-irreversible neuropsychological techniques."

Capsulotomy was developed in the 1950s at Karolinska Institutet, and has been used on an average of two patients a year. The latest operation was performed in 2000.


Story Source:

The above story is based on materials provided by Karolinska Institutet. Note: Materials may be edited for content and length.


Cite This Page:

Karolinska Institutet. "Neurosurgical Treatment Of Anxiety Disorders Effective -- But Risky." ScienceDaily. ScienceDaily, 19 July 2006. <www.sciencedaily.com/releases/2006/07/060719091852.htm>.
Karolinska Institutet. (2006, July 19). Neurosurgical Treatment Of Anxiety Disorders Effective -- But Risky. ScienceDaily. Retrieved July 24, 2014 from www.sciencedaily.com/releases/2006/07/060719091852.htm
Karolinska Institutet. "Neurosurgical Treatment Of Anxiety Disorders Effective -- But Risky." ScienceDaily. www.sciencedaily.com/releases/2006/07/060719091852.htm (accessed July 24, 2014).

Share This




More Mind & Brain News

Thursday, July 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Newsy (July 23, 2014) — An 8-year-old boy helped his younger brother, who has a rare genetic condition that's confined him to a wheelchair, finish a triathlon. Video provided by Newsy
Powered by NewsLook.com
Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Newsy (July 22, 2014) — The 83 new genetic markers could open dozens of new avenues for schizophrenia treatment research. Video provided by Newsy
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) — The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Do Obese Women Have 'Food Learning Impairment'?

Do Obese Women Have 'Food Learning Impairment'?

Newsy (July 18, 2014) — Yale researchers tested 135 men and women, and it was only obese women who were deemed to have "impaired associative learning." Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins