Featured Research

from universities, journals, and other organizations

55,000 Tiny Thomas Jeffersons Show Power Of New Method

Date:
September 27, 2006
Source:
Northwestern University
Summary:
Northwestern University researchers have developed a 55,000-pen, two-dimensional array that allows them to simultaneously create 55,000 identical patterns drawn with tiny dots of molecular ink on substrates of gold or glass. Each structure is only a single molecule tall. This is an advance of a patterning method called Dip-Pen Nanolithography, which was invented at Northwestern. To demonstrate the technique's power, the researchers reproduced the face of Thomas Jefferson from a five-cent coin 55,000 times.

The background shows some of the 55,000 miniature images of a 2005 U.S. nickel made with Dip-Pen Lithography. (Each circle is only twice the diameter of a red blood cell.) Each nickel image with Thomas Jefferson’s profile (in red) is made of a series of 80-nanometer dots. The inset (right) is an electron microscope image of a portion of the 55,000-pen array.
Credit: Image courtesy of Northwestern University

Ever since the invention of the first scanning probe microscope in 1981, researchers have believed the powerful tool would someday be used for the nanofabrication and nanopatterning of surfaces in a molecule-by-molecule, bottom-up fashion. Despite 25 years of research in this area, the world has hit a brick wall in developing a technique with commercial potential -- until now.

Northwestern University researchers have developed a 55,000-pen, two-dimensional array that allows them to simultaneously create 55,000 identical patterns drawn with tiny dots of molecular ink on substrates of gold or glass. Each structure is only a single molecule tall.

This advance of a patterning method called Dip-Pen Nanolithography (DPN), which was invented at Northwestern in 1999, was published online Monday (Sept. 25) by the journal Angewandte Chemie.

To demonstrate the technique's power, the researchers reproduced the face of Thomas Jefferson from a five-cent coin 55,000 times, which took only 30 minutes. Each identical nickel image is 12 micrometers wide -- about twice the diameter of a red blood cell -- and is made up of 8,773 dots, each 80 nanometers in diameter.

The parallel process paves the way for making DPN competitive with other optical and stamping lithographic methods used for patterning large areas on metal and semiconductor substrates, including silicon wafers. The advantage of DPN, which is a maskless lithography, is that it can be used to deliver many different types of inks simultaneously to a surface in any configuration one desires. Mask-based lithographies and stamping protocols are extremely limited in this regard.

"This development should lead to massively miniaturized gene chips, combinatorial libraries for screening pharmaceutically active materials and new ways of fabricating and integrating nanoscale or even molecular-scale components for electronics and computers," said Chad A. Mirkin, director of Northwestern's International Institute for Nanotechnology and George B. Rathmann Professor of Chemistry, who led the research.

"In addition, it could lead to new ways of studying biological systems at the single particle level, which is important for understanding how cancer cells and viruses work and for getting them to stop what they do," he said. "Essentially one can build an entire gene or protein chip that fits underneath a single cell."

In addition to Mirkin, other authors on the paper are Khalid Salaita (lead author), Yuhuang Wang and Rafael A. Vega, from Northwestern; Joseph Fragala, from NanoInk, Inc.; and Chang Liu, from the University of Illinois at Urbana-Champaign.

The research was supported by the National Institutes of Health, the Defense Advanced Research Projects Agency, the Air Force Office of Scientific Research and the National Science Foundation.


Story Source:

The above story is based on materials provided by Northwestern University. Note: Materials may be edited for content and length.


Cite This Page:

Northwestern University. "55,000 Tiny Thomas Jeffersons Show Power Of New Method." ScienceDaily. ScienceDaily, 27 September 2006. <www.sciencedaily.com/releases/2006/09/060926171125.htm>.
Northwestern University. (2006, September 27). 55,000 Tiny Thomas Jeffersons Show Power Of New Method. ScienceDaily. Retrieved July 24, 2014 from www.sciencedaily.com/releases/2006/09/060926171125.htm
Northwestern University. "55,000 Tiny Thomas Jeffersons Show Power Of New Method." ScienceDaily. www.sciencedaily.com/releases/2006/09/060926171125.htm (accessed July 24, 2014).

Share This




More Matter & Energy News

Thursday, July 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Robot Parking Valet Creates Stress-Free Travel

Robot Parking Valet Creates Stress-Free Travel

AP (July 23, 2014) 'Ray' the robotic parking valet at Dusseldorf Airport in Germany lets travelers to avoid the hassle of finding a parking spot before heading to the check-in desk. (July 23) Video provided by AP
Powered by NewsLook.com
Boeing Ups Outlook on 52% Profit Jump

Boeing Ups Outlook on 52% Profit Jump

Reuters - Business Video Online (July 23, 2014) Commercial aircraft deliveries rose seven percent at Boeing, prompting the aerospace company to boost full-year profit guidance- though quarterly revenues missed analyst estimates. Bobbi Rebell reports. Video provided by Reuters
Powered by NewsLook.com
Europe's Car Market on the Rebound?

Europe's Car Market on the Rebound?

Reuters - Business Video Online (July 23, 2014) Daimler kicks off a round of second-quarter earnings results from Europe's top carmakers with a healthy set of numbers - prompting hopes that stronger sales in Europe will counter weakness in emerging markets. Hayley Platt reports. Video provided by Reuters
Powered by NewsLook.com
9/11 Commission Members Warn of Terror "fatigue" Among American Public

9/11 Commission Members Warn of Terror "fatigue" Among American Public

Reuters - US Online Video (July 22, 2014) Ten years after releasing its initial report, members of the 9/11 Commission warn of the "waning sense of urgency" in combating terrorists attacks. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins