Featured Research

from universities, journals, and other organizations

Oral Contraceptives Increase Risk For Breast Cancer In Some Women, Meta-analysis Finds

Date:
October 31, 2006
Source:
Mayo Clinic
Summary:
A meta-analysis published in the October issue of Mayo Clinic Proceedings indicts oral contraceptives as putting premenopausal women at significantly increased risk for breast cancer, especially women who use them prior to having a child.

A meta-analysis published in the October issue of Mayo Clinic Proceedings indicts oral contraceptives as putting premenopausal women at significantly increased risk for breast cancer, especially women who use them prior to having a child.

Related Articles


The meta-analysis builds on many studies with similar findings. But even as the findings stack up, many women are unaware of the risks posed by oral contraceptive use prior to pregnancy, says lead study author Chris Kahlenborn, M.D., of Altoona Hospital in Altoona, Pa.

Dr. Kahlenborn says the discrepancy between risk and patient awareness prompted the meta-analysis, which involved extracting data from 34 studies on whether oral contraceptive (OC) use is associated with premenopausal breast cancer. Included in the studies were women who were premenopausal or younger than 50 and who had been, in most cases, diagnosed with breast cancer during or after 1980.

"As I studied the medical literature, I noticed that a trend appeared," says Dr. Kahlenborn. "Namely, OC use prior to first-term pregnancy seemed to consistently increase the risk of premenopausal breast cancer. Although the trend was apparent, premenopausal women have continued to hear that OCs are basically safe."

Rather, patients should know that sustained oral contraceptive use prior to pregnancy increases a premenopausal woman's risk of developing breast cancer, saysDr. Kahlenborn. He says physicians should better inform their patients of the risks associated with oral contraceptives and calls it a "clear-cut informed consent issue."

The study noted that 21 out of 23 retrospective studies have shown an increased risk of breast cancer in women who took oral contraceptives prior to pregnancy. It also showed that those women experienced an increased risk of 44 percent.

What's more, in 2005, the World Health Organization officially classified oral contraceptives as a class one carcinogen, the study's authors say.

These are staggering results given that more that more than 45,000 women each year develop breast cancer prior to menopause, Dr. Kahlenborn says.

"My hope is that physicians will provide more detailed information to their patients about hormonal contraceptives," he says. "The authors of our meta-analysis believe that women deserve to be fully informed."

Other authors of the meta-analysis study are Francesmary Modugno, Ph.D., and Douglas Potter, Ph.D., both of the University of Pittsburgh Cancer Institute, and Walter Severs, Ph.D., of Pennsylvania State University in University Park.


Story Source:

The above story is based on materials provided by Mayo Clinic. Note: Materials may be edited for content and length.


Cite This Page:

Mayo Clinic. "Oral Contraceptives Increase Risk For Breast Cancer In Some Women, Meta-analysis Finds." ScienceDaily. ScienceDaily, 31 October 2006. <www.sciencedaily.com/releases/2006/10/061030143351.htm>.
Mayo Clinic. (2006, October 31). Oral Contraceptives Increase Risk For Breast Cancer In Some Women, Meta-analysis Finds. ScienceDaily. Retrieved November 23, 2014 from www.sciencedaily.com/releases/2006/10/061030143351.htm
Mayo Clinic. "Oral Contraceptives Increase Risk For Breast Cancer In Some Women, Meta-analysis Finds." ScienceDaily. www.sciencedaily.com/releases/2006/10/061030143351.htm (accessed November 23, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, November 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com
Raw: Paralyzed Marine Walks With Robotic Braces

Raw: Paralyzed Marine Walks With Robotic Braces

AP (Nov. 21, 2014) Marine Corps officials say a special operations officer left paralyzed by a sniper's bullet in Afghanistan walked using robotic leg braces in a ceremony to award him a Bronze Star. (Nov. 21) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins