Featured Research

from universities, journals, and other organizations

Simple, Noninvasive Test Measures Survival Time In Adult Pulmonary Hypertension

Date:
November 3, 2006
Source:
American Thoracic Society
Summary:
Researchers have developed a simple, noninvasive way to measure right ventricular function in the heart to predict survival of adults who suffer from pulmonary hypertension. The research appears in the first issue for November 2006 of the American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society.

Researchers have developed a simple, noninvasive way to measure right ventricular function in the heart to predict survival of adults who suffer from pulmonary hypertension.

Related Articles


The research appears in the first issue for November 2006 of the American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society.

Paul M. Hassoun, M.D., of the Divisions of Cardiology, Pulmonary and Critical Care Medicine at Johns Hopkins Hospital in Baltimore, and 11 associates studied 63 consecutive patients with pulmonary hypertension. After right heart catheterization, these patients underwent a transthoracic echocardiogram to assess right ventricular performance in the heart.

Study participants were mostly female, white and had an average age of 55. Seventy-five percent (47 patients) met the World Health Organization's group 1 diagnostic classification of pulmonary hypertension.

Pulmonary hypertension involves progressive narrowing of the blood vessels in the lungs, which can lead to death. In 2000, 163,000 patients discharged from U.S. hospitals had been diagnosed with primary pulmonary hypertension. Although the problem is difficult to detect in a routine medical exam, doctors see more rapid clinical deterioration in patients who have the greatest degree of right ventricular dysfunction.

To assess the problem, researchers performed a test called tricuspid annular plane systolic excursion (TAPSE), which measures echocardiographic abnormalities in the tricuspid valve. Located between the heart's right atrium and right ventricle, the valve prevents the backflow of blood as it is pumped from the right atrium to the right ventricle.

"We found that a TAPSE of less than 1.8 cm was associated with a greater ventricular systolic dysfunction, as well as right heart remodeling," said Dr. Hassoun. "In addition, survival estimates at one and two years for those with pulmonary arterial hypertension were 94 percent and 88 percent, respectively, for individuals with a TAPSE of 1.8 cm or greater. If the TAPSE was less, the survival rates were 60 percent at one year and 50 percent at two years."

The researchers said that patients with a TAPSE of less than 1.8 cm, showing more advanced right ventricular dysfunction, had a dramatically reduced survival rate over the average follow-up time of 19 months. Patients with a TAPSE of less than 1.5 cm had an especially poor outcome.

"Our results suggest that TAPSE is a robust measure of right ventricular function and a powerful predictor of patient survival in pulmonary hypertension," said Dr. Hassoun.

The investigators noted that they believed the TAPSE test should be incorporated into the echocardiographic assessment of all patients were pulmonary artery hypertension.


Story Source:

The above story is based on materials provided by American Thoracic Society. Note: Materials may be edited for content and length.


Cite This Page:

American Thoracic Society. "Simple, Noninvasive Test Measures Survival Time In Adult Pulmonary Hypertension." ScienceDaily. ScienceDaily, 3 November 2006. <www.sciencedaily.com/releases/2006/11/061101151436.htm>.
American Thoracic Society. (2006, November 3). Simple, Noninvasive Test Measures Survival Time In Adult Pulmonary Hypertension. ScienceDaily. Retrieved March 5, 2015 from www.sciencedaily.com/releases/2006/11/061101151436.htm
American Thoracic Society. "Simple, Noninvasive Test Measures Survival Time In Adult Pulmonary Hypertension." ScienceDaily. www.sciencedaily.com/releases/2006/11/061101151436.htm (accessed March 5, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, March 5, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Adults Only Get The Flu Twice A Decade, Researchers Say

Adults Only Get The Flu Twice A Decade, Researchers Say

Newsy (Mar. 4, 2015) Researchers found adults only get the flu about once every five years. Scientists analyzed how a person&apos;s immunity builds up over time as well. Video provided by Newsy
Powered by NewsLook.com
New Hormone Could Protect Against Diabetes And Weight Gain

New Hormone Could Protect Against Diabetes And Weight Gain

Newsy (Mar. 4, 2015) A newly discovered hormone mimics the effects of exercise, protecting against diabetes and weight gain. Video provided by Newsy
Powered by NewsLook.com
Mount Everest Has a Poop Problem

Mount Everest Has a Poop Problem

Buzz60 (Mar. 4, 2015) With no bathrooms to use, climbers of Mount Everest have been leaving human waste on the mountain for years, and it&apos;s becoming a health issue. Mike Janela (@mikejanela) has more. Video provided by Buzz60
Powered by NewsLook.com
The Best Tips to 'Skinny' Your Home

The Best Tips to 'Skinny' Your Home

Buzz60 (Mar. 4, 2015) If you&apos;re looking to reach your health goals this season, there are a few simple tips to help you spring clean your space and improve your nutrition. Krystin Goodwin (@krystingoodwin) has the skinny on keeping a healthy home. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins