Featured Research

from universities, journals, and other organizations

Longer Hormone Therapy Doesn't Help Prostate Cancer Patients Live Longer, Study Finds

Date:
November 6, 2006
Source:
American Society for Therapeutic Radiology and Oncology
Summary:
Prostate cancer patients treated with either radiation or surgery who use hormone therapy for longer than six months do not survive any longer than patients who use the treatment for a shorter amount of time, according to a study presented November 5, 2006, at the American Society for Therapeutic Radiology and Oncology's 48th Annual Meeting in Philadelphia.

Prostate cancer patients treated with either radiation or surgery who use hormone therapy for longer than six months do not survive any longer than patients who use the treatment for a shorter amount of time, according to a study presented November 5, 2006, at the American Society for Therapeutic Radiology and Oncology's 48th Annual Meeting in Philadelphia.

"Many patients with high risk prostate cancer are treated with two or more years of hormone therapy based on studies performed over a decade ago," said Cliff Robinson, M.D., lead author of the study and a radiation oncologist at Cleveland Clinic in Cleveland, Ohio. "Our study's findings suggest that treating current patients with shorter-term hormone therapy may not only be equally effective, but also improve their quality of life, due to a lesser degree of treatment side effects."

The authors also found that patients receiving longer than six months of hormone therapy were twice as likely to die as patients who use the treatment for a shorter amount of time. "The reasons why patients receiving longer term hormone therapy may do worse are unclear," said Dr. Robinson, who also cautions, "A number of factors could complicate the issue, and this area needs further investigation before any conclusions can be drawn."

Androgen deprivation therapy is a hormone therapy used to treat prostate cancer by lowering the level of male hormones (androgens) to shrink or slow down the growth of prostate cancer. It has been shown to dramatically slow advanced prostate cancer that has already spread to the lymph nodes or the bone, and improves survival when combined with radiation therapy in advanced prostate cancer that has not already spread.

Several side effects are common to androgen deprivation therapy and are a direct result of decreased androgen levels. Side effects vary significantly depending on the amount and length of time the hormone therapy is given. Potential side effects include reduced sexual desire, impotence, hot flashes, weakening of the bones, breast tenderness or breast growth, as well as other conditions.

The study reviewed 579 patients who were treated at the Cleveland Clinic with high risk prostate cancer from 1996 to 2003. These patients were divided into three groups - one that received no androgen deprivation therapy, one that had received six months or less of androgen deprivation therapy, and one that received more than six months of treatment - to determine if longer use of hormone therapy stopped cancer from growing and lengthened survival.


Story Source:

The above story is based on materials provided by American Society for Therapeutic Radiology and Oncology. Note: Materials may be edited for content and length.


Cite This Page:

American Society for Therapeutic Radiology and Oncology. "Longer Hormone Therapy Doesn't Help Prostate Cancer Patients Live Longer, Study Finds." ScienceDaily. ScienceDaily, 6 November 2006. <www.sciencedaily.com/releases/2006/11/061106094809.htm>.
American Society for Therapeutic Radiology and Oncology. (2006, November 6). Longer Hormone Therapy Doesn't Help Prostate Cancer Patients Live Longer, Study Finds. ScienceDaily. Retrieved September 18, 2014 from www.sciencedaily.com/releases/2006/11/061106094809.htm
American Society for Therapeutic Radiology and Oncology. "Longer Hormone Therapy Doesn't Help Prostate Cancer Patients Live Longer, Study Finds." ScienceDaily. www.sciencedaily.com/releases/2006/11/061106094809.htm (accessed September 18, 2014).

Share This



More Health & Medicine News

Thursday, September 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Cost of Ebola

The Cost of Ebola

Reuters - Business Video Online (Sep. 18, 2014) As Sierra Leone prepares for a three-day "lockdown" in its latest bid to stem the spread of Ebola, Ciara Lee looks at the financial implications of fighting the largest ever outbreak of the disease. Video provided by Reuters
Powered by NewsLook.com
What HealthKit Bug Means For Your iOS Fitness Apps

What HealthKit Bug Means For Your iOS Fitness Apps

Newsy (Sep. 18, 2014) Apple has delayed the launch of the HealthKit app platform, citing a bug. Video provided by Newsy
Powered by NewsLook.com
Residents Vaccinated as Haiti Fights Cholera Epidemic

Residents Vaccinated as Haiti Fights Cholera Epidemic

AFP (Sep. 18, 2014) Haitians receive the second dose of the vaccine against cholera as part of the UN's vaccination campaign. Duration: 00:34 Video provided by AFP
Powered by NewsLook.com
Artificial Sweetener Could Promote Diabetes

Artificial Sweetener Could Promote Diabetes

Newsy (Sep. 17, 2014) Doctors once thought artificial sweeteners lacked the health risks of sugar, but a new study says they can impact blood sugar levels the same way. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins