Featured Research

from universities, journals, and other organizations

Researchers Find Evidence For Traumatic Cause Of Carpal Tunnel Syndrome

Date:
November 10, 2006
Source:
Mayo Clinic
Summary:
New Mayo Clinic research suggests that a shearing injury of the tissue that lines the tendons within the carpal tunnel may cause carpal tunnel syndrome, a debilitating condition of the wrist and hand.

New Mayo Clinic research suggests that a shearing injury of the tissue that lines the tendons within the carpal tunnel may cause carpal tunnel syndrome, a debilitating condition of the wrist and hand. If validated by further research, Mayo's study comparing electron microscope images of carpal tunnel syndrome tissue with those from normal tissue could lead to earlier diagnosis and possibly better treatments for preventing or reversing carpal tunnel syndrome.

Related Articles


The study appears in the November issue of Plastic and Reconstructive Surgery.

In the study, the Mayo researchers present data which suggest that the carpal tunnel syndrome disease process begins with a shearing injury. As the injury heals, the resulting scar tissue impedes the sliding motion of the tendon, compresses the median nerve, cuts off the nerve's blood supply and eventually leads to the pressure buildup characteristic of carpal tunnel syndrome, a condition that affects an estimated five percent of adults. The end result of this process is the familiar carpal tunnel syndrome symptoms of hand pain, numbness and tingling associated with carpal tunnel syndrome.

Significance of the Mayo Clinic Research

The Mayo research offers an explanation for the cause of carpal tunnel syndrome. Although carpal tunnel syndrome is a well-recognized condition, in most cases the specific cause has been unknown. What is well known is that a pressure buildup in the carpal tunnel affects the circulation nourishing the nerves, which can lead to pain, numbness and tingling. The question Mayo researchers explored was: What leads to the pressure buildup? Their results indicating shearing injury as a possible cause present promising new ways to approach treating carpal tunnel syndrome.

The Mayo work is significant because it:

  • provides a detailed analysis of carpal tunnel syndrome tissue abnormalities
  • shows that the tissue closest to the tendon is the most disturbed, thus providing circumstantial evidence to support the presence of a shearing injury in carpal tunnel patients that is not present in individuals without the condition
  • points to new directions for designing better ways to diagnose and possibly treat carpal tunnel syndrome by addressing a first cause of carpal tunnel syndrome, the shearing injury to the tendon lining

"The idea is that if we can identify the sequence of events that lead to carpal tunnel syndrome, we can design more effective interventions to prevent or reverse it," according to Peter Amadio, M.D., the Mayo Clinic orthopedic surgeon who led the NIH-funded research team.

While rest, exercise and some medications can treat carpal tunnel syndrome, severe carpal tunnel syndrome is commonly treated surgically to release the pressure buildup.

The study did not specifically probe the cause of the shearing injuries, but Dr. Amadio says the team is researching the role of trauma or stress to the tissue lining from repeated finger movements. "Such shearing injuries could be the result of marked or repetitive differential motion of adjacent digits, and may support the hypothesis of a traumatic cause for carpal tunnel syndrome," he says.

Collaboration and Support

In addition to Dr. Amadio, the Mayo Clinic research team included: Anke Ettema, M.D.; Chunfeng Zhao, M.D.; Lester Wold, M.D.; Megan O'Byrne, M.A.; Steven Moran, M.D.; and Kai-Nan An, Ph.D.

The study was funded by the National Institutes of Health and the Mayo Clinic.


Story Source:

The above story is based on materials provided by Mayo Clinic. Note: Materials may be edited for content and length.


Cite This Page:

Mayo Clinic. "Researchers Find Evidence For Traumatic Cause Of Carpal Tunnel Syndrome." ScienceDaily. ScienceDaily, 10 November 2006. <www.sciencedaily.com/releases/2006/11/061109153942.htm>.
Mayo Clinic. (2006, November 10). Researchers Find Evidence For Traumatic Cause Of Carpal Tunnel Syndrome. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2006/11/061109153942.htm
Mayo Clinic. "Researchers Find Evidence For Traumatic Cause Of Carpal Tunnel Syndrome." ScienceDaily. www.sciencedaily.com/releases/2006/11/061109153942.htm (accessed October 31, 2014).

Share This



More Health & Medicine News

Friday, October 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Melafind: Spotting Melanoma Without a Biopsy

Melafind: Spotting Melanoma Without a Biopsy

Ivanhoe (Oct. 31, 2014) The MelaFind device is a pain-free way to check suspicious moles for melanoma, without the need for a biopsy. Video provided by Ivanhoe
Powered by NewsLook.com
Battling Multiple Myeloma

Battling Multiple Myeloma

Ivanhoe (Oct. 31, 2014) The answer isn’t always found in new drugs – repurposing an ‘old’ drug that could mean better multiple myeloma treatment, and hope. Video provided by Ivanhoe
Powered by NewsLook.com
Chronic Inflammation and Prostate Cancer

Chronic Inflammation and Prostate Cancer

Ivanhoe (Oct. 31, 2014) New information that is linking chronic inflammation in the prostate and prostate cancer, which may help doctors and patients prevent cancer in the future. Video provided by Ivanhoe
Powered by NewsLook.com
Sickle Cell: Stopping Kids’ Silent Strokes

Sickle Cell: Stopping Kids’ Silent Strokes

Ivanhoe (Oct. 31, 2014) Blood transfusions are proving crucial to young sickle cell patients by helping prevent strokes, even when there is no outward sign of brain injury. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins