Featured Research

from universities, journals, and other organizations

Changes In Brain Density Can Help Predict Schizophrenia

Date:
December 11, 2006
Source:
BioMed Central
Summary:
Changes in brain density could be used to predict whether an individual who is at risk for schizophrenia is likely to develop the condition or not. A study published today in the open access journal BMC Medicine reveals that monitoring changes in grey matter density over time using brain scans could help early detection of individuals who are likely to develop schizophrenia, when used in combination with other prediction methods.

This image is an amalgamation of the MRI scans of the eight study participants who went on to develop schizophrenia. The yellow areas highlight the parts of the brain where scans revealed a reduction in grey matter density.
Credit: Dominic Job

Changes in brain density could be used to predict whether an individual who is at risk for schizophrenia is likely to develop the condition or not. A study published today in the open access journal BMC Medicine reveals that monitoring changes in grey matter density over time using brain scans could help early detection of individuals who are likely to develop schizophrenia, when used in combination with other prediction methods.

Dominic Job and colleagues from the University of Edinburgh in the UK analysed the brain scans of 65 individuals known to be at risk for schizophrenia because members of their family had suffered from it. The scans were generated using structural magnetic resonance imaging techniques (sMRI). Job et al. analysed changes in grey matter density in the scans, over a period of 18 months. Eight of the individuals studied went on to develop schizophrenia, on average 2.3 years after the brain scans were collected.

Job et al.'s results show that a reduction in grey matter density over time could be used as an indicator that an individual who is at risk will develop schizophrenia. Sixty percent of the individuals who according to Job et al.'s results were likely to develop schizophrenia, because they showed a reduction in grey matter in one part of their brain called the temporal gyrus, did develop the condition. Over 90% of the individuals who according to Job et al.'s predictions would not develop schizophrenia, did not develop it. Job et al.'s predictions could be used to assess possibilities for preventing schizophrenia.

Article:
Grey matter changes can improve the prediction of schizophrenia in subjects at high risk
Dominic E Job, Heather C Whalley, Andrew M McIntosh, David GC Owens, Eve C Johnstone and Stephen M Lawrie
BMC Medicine 2006, (in press)
http://www.biomedcentral.com/bmcmed/


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Cite This Page:

BioMed Central. "Changes In Brain Density Can Help Predict Schizophrenia." ScienceDaily. ScienceDaily, 11 December 2006. <www.sciencedaily.com/releases/2006/12/061207160610.htm>.
BioMed Central. (2006, December 11). Changes In Brain Density Can Help Predict Schizophrenia. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2006/12/061207160610.htm
BioMed Central. "Changes In Brain Density Can Help Predict Schizophrenia." ScienceDaily. www.sciencedaily.com/releases/2006/12/061207160610.htm (accessed September 17, 2014).

Share This



More Mind & Brain News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Corporal Punishment on Decline, Debate Renews

Corporal Punishment on Decline, Debate Renews

AP (Sep. 16, 2014) Corporal punishment in the United States is on the decline, but there is renewed debate over its use after Minnesota Vikings running back Adrian Peterson was charged with child abuse. (Sept. 16) Video provided by AP
Powered by NewsLook.com
FDA Eyes Skin Shocks Used at Mass. School

FDA Eyes Skin Shocks Used at Mass. School

AP (Sep. 15, 2014) The FDA is considering whether to ban devices used by the Judge Rotenberg Educational Center in Canton, Massachusetts, the only place in the country known to use electrical skin shocks as aversive conditioning for aggressive patients. (Sept. 15) Video provided by AP
Powered by NewsLook.com
Shocker: Journalists Are Utterly Addicted To Coffee

Shocker: Journalists Are Utterly Addicted To Coffee

Newsy (Sep. 13, 2014) A U.K. survey found that journalists consumed the most amount of coffee, but that's only the tip of the coffee-related statistics iceberg. Video provided by Newsy
Powered by NewsLook.com
'Magic Mushrooms' Could Help Smokers Quit

'Magic Mushrooms' Could Help Smokers Quit

Newsy (Sep. 11, 2014) In a small study, researchers found that the majority of long-time smokers quit after taking psilocybin pills and undergoing therapy sessions. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins