"This is the first study of the neurological reactions to human touch in a threatening situation, and the first study to measure how the brain facilitates the health-enhancing properties of close social relationships," says Dr. James A. Coan, author of the study, which is published in the December 2006 issue of the journal Psychological Science.

Coan, an assistant professor in the U.Va. Neuroscience Graduate Program and the Department of Psychology, conducted a study involving several couples who rated themselves as highly satisfied with their marriages. Coan and colleagues designed a functional MRI (magnetic resonance imaging) study in which 16 married women were subjected to the threat of a very mild electric shock while they by turns held their husband's hand, the hand of a stranger (male) or no hand at all. The MRI was able to show how these women's brains responded to this handholding while in a threatening situation.

The results showed a large decrease in the brain response to threat as a function of spouse handholding, and a limited decrease in this response as a function of stranger handholding. Moreover, spouse handholding effects varied as a function of marital quality, with women in the very highest quality marriages benefiting from a very powerful decrease in threat-related brain activity, including a strong decrease in the emotional (affective) component of the brain's pain processing circuits.

Coan is expanding his functional MRI studies in collaboration with the U.Va. Department of Radiology, to continue his exploration of the neuroscience of emotion and close social relationships.

Note: If no author is given, the source is cited instead.

• Psychology
• Social Psychology
• Relationships
• Neuroscience
• Brain Injury
• Disorders and Syndromes

• Functional neuroimaging
• Thalamus
• Neuropsychology
• Social cognition
• Psychopathology
• Human brain