Featured Research

from universities, journals, and other organizations

Inhaled Steroids May Not Be Enough For Some Children With Asthma

Date:
May 23, 2007
Source:
American Thoracic Society
Summary:
Some children may not be able to keep their asthma under control even if they consistently report using inhaled corticosteroids, a mainstay of asthma treatment, suggests a new study.

Some children may not be able to keep their asthma under control even if they consistently report using inhaled corticosteroids, a mainstay of asthma treatment, suggests a new study.

Related Articles


The study of 914 children with mild to moderate asthma found that over a one-year period, children who reported consistent inhaled steroid use were 20% less likely to report having well-controlled asthma compared with those not using any inhaled steroids. This finding held even when the severity of the children's asthma was taken into account.

"There may be several reasons for our findings; It is possible that some children are genetically less responsive to steroids," says researcher Gregory Sawicki, M.D. of Children's Hospital in Boston. "In addition to issues of medication adherence and inability to completely control for differences in underlying asthma, severity can never be completely ruled out."

Several studies of adults with asthma have suggested that even rigorous use of inhaled steroids doesn't lead to well controlled asthma in all adults, Dr. Sawicki noted. "But this issue hasn't been looked at closely in children," he said. "Further studies are needed to see what is different about children who don't respond to steroids, to see if there is a way to predict whether a child will respond to inhaled steroids."

Of the 914 children in the study, inhaled steroids were recommended for 435 who had persistent asthma, meaning they had symptoms on a regular basis. Among children who weren't recommended for inhaled steroid treatment, most reported well-controlled asthma. Among those recommended for inhaled steroid treatment, 44% reported consistently using the medicine; 35% said they intermittently used the medicine and 21% said they didn't use it at all.

"The majority of children with mild asthma are less likely to have symptoms as they get older and may not need to be on daily steroids," Dr. Sawicki said. "The flip side is that if a child has poor asthma control, the parents and doctor need to make sure the child is adhering to their inhaled steroid treatment. But variation in response to inhaled steroids, as other medications, is well described."

The data comes from the Child Asthma Management Program Continuation Study (CAMPCS), one of the largest groups of children with mild to moderate asthma in the nation who have been followed over 10 years. "This study gives us a good sense of real-world practice in asthma management," Dr. Sawicki says. "The children's care is not directed by anyone in the study; it's an observation of what goes on when the children's care is directed by their own physicians."

This study was presented at the American Thoracic Society 2007 International Conference, on Wednesday, May 23. "Patterns of Inhaled Steroid (ICS) Use and Asthma Control in Childhood Asthma Management Program Continuation Study" (Session D92; Abstract # 1393)


Story Source:

The above story is based on materials provided by American Thoracic Society. Note: Materials may be edited for content and length.


Cite This Page:

American Thoracic Society. "Inhaled Steroids May Not Be Enough For Some Children With Asthma." ScienceDaily. ScienceDaily, 23 May 2007. <www.sciencedaily.com/releases/2007/05/070522142058.htm>.
American Thoracic Society. (2007, May 23). Inhaled Steroids May Not Be Enough For Some Children With Asthma. ScienceDaily. Retrieved December 19, 2014 from www.sciencedaily.com/releases/2007/05/070522142058.htm
American Thoracic Society. "Inhaled Steroids May Not Be Enough For Some Children With Asthma." ScienceDaily. www.sciencedaily.com/releases/2007/05/070522142058.htm (accessed December 19, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, December 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
Dads-To-Be Also Experience Hormone Changes During Pregnancy

Dads-To-Be Also Experience Hormone Changes During Pregnancy

Newsy (Dec. 18, 2014) A study from University of Michigan researchers found that expectant fathers see a decrease in testosterone as the baby's birth draws near. Video provided by Newsy
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins