Featured Research

from universities, journals, and other organizations

Inhaled Steroids May Not Be Enough For Some Children With Asthma

Date:
May 23, 2007
Source:
American Thoracic Society
Summary:
Some children may not be able to keep their asthma under control even if they consistently report using inhaled corticosteroids, a mainstay of asthma treatment, suggests a new study.

Some children may not be able to keep their asthma under control even if they consistently report using inhaled corticosteroids, a mainstay of asthma treatment, suggests a new study.

The study of 914 children with mild to moderate asthma found that over a one-year period, children who reported consistent inhaled steroid use were 20% less likely to report having well-controlled asthma compared with those not using any inhaled steroids. This finding held even when the severity of the children's asthma was taken into account.

"There may be several reasons for our findings; It is possible that some children are genetically less responsive to steroids," says researcher Gregory Sawicki, M.D. of Children's Hospital in Boston. "In addition to issues of medication adherence and inability to completely control for differences in underlying asthma, severity can never be completely ruled out."

Several studies of adults with asthma have suggested that even rigorous use of inhaled steroids doesn't lead to well controlled asthma in all adults, Dr. Sawicki noted. "But this issue hasn't been looked at closely in children," he said. "Further studies are needed to see what is different about children who don't respond to steroids, to see if there is a way to predict whether a child will respond to inhaled steroids."

Of the 914 children in the study, inhaled steroids were recommended for 435 who had persistent asthma, meaning they had symptoms on a regular basis. Among children who weren't recommended for inhaled steroid treatment, most reported well-controlled asthma. Among those recommended for inhaled steroid treatment, 44% reported consistently using the medicine; 35% said they intermittently used the medicine and 21% said they didn't use it at all.

"The majority of children with mild asthma are less likely to have symptoms as they get older and may not need to be on daily steroids," Dr. Sawicki said. "The flip side is that if a child has poor asthma control, the parents and doctor need to make sure the child is adhering to their inhaled steroid treatment. But variation in response to inhaled steroids, as other medications, is well described."

The data comes from the Child Asthma Management Program Continuation Study (CAMPCS), one of the largest groups of children with mild to moderate asthma in the nation who have been followed over 10 years. "This study gives us a good sense of real-world practice in asthma management," Dr. Sawicki says. "The children's care is not directed by anyone in the study; it's an observation of what goes on when the children's care is directed by their own physicians."

This study was presented at the American Thoracic Society 2007 International Conference, on Wednesday, May 23. "Patterns of Inhaled Steroid (ICS) Use and Asthma Control in Childhood Asthma Management Program Continuation Study" (Session D92; Abstract # 1393)


Story Source:

The above story is based on materials provided by American Thoracic Society. Note: Materials may be edited for content and length.


Cite This Page:

American Thoracic Society. "Inhaled Steroids May Not Be Enough For Some Children With Asthma." ScienceDaily. ScienceDaily, 23 May 2007. <www.sciencedaily.com/releases/2007/05/070522142058.htm>.
American Thoracic Society. (2007, May 23). Inhaled Steroids May Not Be Enough For Some Children With Asthma. ScienceDaily. Retrieved September 30, 2014 from www.sciencedaily.com/releases/2007/05/070522142058.htm
American Thoracic Society. "Inhaled Steroids May Not Be Enough For Some Children With Asthma." ScienceDaily. www.sciencedaily.com/releases/2007/05/070522142058.htm (accessed September 30, 2014).

Share This



More Health & Medicine News

Tuesday, September 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How 'Yes Means Yes' Defines Sexual Assault

How 'Yes Means Yes' Defines Sexual Assault

Newsy (Sep. 29, 2014) Aimed at reducing sexual assaults on college campuses, California has adopted a new law changing the standard of consent for sexual activity. Video provided by Newsy
Powered by NewsLook.com
Scientists May Have Found An Early Sign Of Pancreatic Cancer

Scientists May Have Found An Early Sign Of Pancreatic Cancer

Newsy (Sep. 29, 2014) Researchers looked at 1,500 blood samples and determined people who developed pancreatic cancer had more branched chain amino acids. Video provided by Newsy
Powered by NewsLook.com
Colo. Doctors See Cluster of Enterovirus Cases

Colo. Doctors See Cluster of Enterovirus Cases

AP (Sep. 29, 2014) Doctors at the Children's Hospital of Colorado say they have treated over 4,000 children with serious respiratory illnesses since August. Nine of the patients have shown distinct neurological symptoms, including limb weakness. (Sept. 29) Video provided by AP
Powered by NewsLook.com
Dr.'s Unsure of Cause of Fast-Spreading Virus

Dr.'s Unsure of Cause of Fast-Spreading Virus

AP (Sep. 29, 2014) Doctors at the Children's Hospital of Colorado say they have treated over 4,000 children with serious respiratory illnesses since August. Nine of the patients have shown distinct neurological symptoms, including limb weakness. (Sept. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins