Featured Research

from universities, journals, and other organizations

Preimplantation Genetic Diagnosis Okay For Test-tube Babies, Study Finds

Date:
June 18, 2007
Source:
European Society of Human Genetics
Summary:
Children born after embryo biopsy for preimplantation genetic diagnosis do not show any more major malformations than those born after artificial reproduction technologies without PGD.

Children born after embryo biopsy for preimplantation genetic diagnosis (PGD) do not show any more major malformations than those born after artificial reproduction technologies (ART) without PGD, a scientist will tell the annual conference of the European Society of Human Genetics today. Professor Ingeborg Liebaers, from the Research Centre for Reproductive Genetics, Free University of Brussels, Brussels, Belgium, will say that the results of her study of 583 children born after PGD was reassuring.

PGD is a new option for couples at risk of transmitting genetic diseases. Instead of carrying out a prenatal diagnosis followed by a termination of pregnancy, in vitro fertilisation (IVF) with intracytoplasmic sperm injection (where a sperm is injected directly into an egg) is performed, followed by genetic testing of the embryos. Only unaffected embryos are subsequently transferred to the womb.

"Because embryos are biopsied in PGD procedures, and this constitutes an additional manipulation of a delicate organism, we set out to study whether this had any effect on the health of children who were born as a result of this procedure", says Professor Liebaers. The scientists first collected data on the pregnancies by giving questionnaires to patients on the day of the embryo transfer. Additional questionnaires were sent during pregnancy, at delivery, and later on to the patients, their gynaecologists, and paediatricians. Children were examined at 2 months and 2 years old.

"After embryo transfer, 563 children of the 583 were liveborn, 20 were stillborn, and 9 died neonatally. It seems that the perinatal death rate is higher, especially in multiple pregnancies, then in IVF and ICSi children. We need to further investigate these perinatal death rates," says Professor Liebaers, "but we were encouraged to find that the major malformation rate was only 3.6%, or no higher than that which is found in children born after conventional IVF and ICSI."

The average length of the pregnancies of singleton births was 38.8 weeks and the mean birthweight 3.268 kg, comparable to those of IVF and ICSI children, she says.

"The study is the first of a large series of PGD children from one centre", Professor Liebaers will tell the conference, "and we will be carrying out further follow-up as these children grow older. But we feel that results to date are reassuring; it is good to know that a procedure that can offer patients hope of having a baby unaffected by serious disease is also safe in the longer-term."


Story Source:

The above story is based on materials provided by European Society of Human Genetics. Note: Materials may be edited for content and length.


Cite This Page:

European Society of Human Genetics. "Preimplantation Genetic Diagnosis Okay For Test-tube Babies, Study Finds." ScienceDaily. ScienceDaily, 18 June 2007. <www.sciencedaily.com/releases/2007/06/070616191628.htm>.
European Society of Human Genetics. (2007, June 18). Preimplantation Genetic Diagnosis Okay For Test-tube Babies, Study Finds. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2007/06/070616191628.htm
European Society of Human Genetics. "Preimplantation Genetic Diagnosis Okay For Test-tube Babies, Study Finds." ScienceDaily. www.sciencedaily.com/releases/2007/06/070616191628.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Stone Fruit Listeria Scare Causes Sweeping Recall

Stone Fruit Listeria Scare Causes Sweeping Recall

Newsy (July 22, 2014) The Wawona Packing Company has issued a voluntary recall on the stone fruit it distributes due to a possible Listeria outbreak. Video provided by Newsy
Powered by NewsLook.com
Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Newsy (July 22, 2014) The 83 new genetic markers could open dozens of new avenues for schizophrenia treatment research. Video provided by Newsy
Powered by NewsLook.com
CDC Head Concerned About a Post-Antibiotic Era

CDC Head Concerned About a Post-Antibiotic Era

AP (July 22, 2014) Sounding alarms about the growing threat of antibiotic resistance, CDC Director Tom Frieden warned Tuesday if the global community does not confront the problem soon, the world will be living in a devastating post-antibiotic era. (July 22) Video provided by AP
Powered by NewsLook.com
Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins