Featured Research

from universities, journals, and other organizations

Preimplantation Genetic Diagnosis Okay For Test-tube Babies, Study Finds

Date:
June 18, 2007
Source:
European Society of Human Genetics
Summary:
Children born after embryo biopsy for preimplantation genetic diagnosis do not show any more major malformations than those born after artificial reproduction technologies without PGD.

Children born after embryo biopsy for preimplantation genetic diagnosis (PGD) do not show any more major malformations than those born after artificial reproduction technologies (ART) without PGD, a scientist will tell the annual conference of the European Society of Human Genetics today. Professor Ingeborg Liebaers, from the Research Centre for Reproductive Genetics, Free University of Brussels, Brussels, Belgium, will say that the results of her study of 583 children born after PGD was reassuring.

PGD is a new option for couples at risk of transmitting genetic diseases. Instead of carrying out a prenatal diagnosis followed by a termination of pregnancy, in vitro fertilisation (IVF) with intracytoplasmic sperm injection (where a sperm is injected directly into an egg) is performed, followed by genetic testing of the embryos. Only unaffected embryos are subsequently transferred to the womb.

"Because embryos are biopsied in PGD procedures, and this constitutes an additional manipulation of a delicate organism, we set out to study whether this had any effect on the health of children who were born as a result of this procedure", says Professor Liebaers. The scientists first collected data on the pregnancies by giving questionnaires to patients on the day of the embryo transfer. Additional questionnaires were sent during pregnancy, at delivery, and later on to the patients, their gynaecologists, and paediatricians. Children were examined at 2 months and 2 years old.

"After embryo transfer, 563 children of the 583 were liveborn, 20 were stillborn, and 9 died neonatally. It seems that the perinatal death rate is higher, especially in multiple pregnancies, then in IVF and ICSi children. We need to further investigate these perinatal death rates," says Professor Liebaers, "but we were encouraged to find that the major malformation rate was only 3.6%, or no higher than that which is found in children born after conventional IVF and ICSI."

The average length of the pregnancies of singleton births was 38.8 weeks and the mean birthweight 3.268 kg, comparable to those of IVF and ICSI children, she says.

"The study is the first of a large series of PGD children from one centre", Professor Liebaers will tell the conference, "and we will be carrying out further follow-up as these children grow older. But we feel that results to date are reassuring; it is good to know that a procedure that can offer patients hope of having a baby unaffected by serious disease is also safe in the longer-term."


Story Source:

The above story is based on materials provided by European Society of Human Genetics. Note: Materials may be edited for content and length.


Cite This Page:

European Society of Human Genetics. "Preimplantation Genetic Diagnosis Okay For Test-tube Babies, Study Finds." ScienceDaily. ScienceDaily, 18 June 2007. <www.sciencedaily.com/releases/2007/06/070616191628.htm>.
European Society of Human Genetics. (2007, June 18). Preimplantation Genetic Diagnosis Okay For Test-tube Babies, Study Finds. ScienceDaily. Retrieved September 19, 2014 from www.sciencedaily.com/releases/2007/06/070616191628.htm
European Society of Human Genetics. "Preimplantation Genetic Diagnosis Okay For Test-tube Babies, Study Finds." ScienceDaily. www.sciencedaily.com/releases/2007/06/070616191628.htm (accessed September 19, 2014).

Share This



More Health & Medicine News

Friday, September 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com
How The 'Angelina Jolie Effect' Increased Cancer Screenings

How The 'Angelina Jolie Effect' Increased Cancer Screenings

Newsy (Sep. 19, 2014) Angelina's Jolie's decision to undergo a preventative mastectomy in 2013 inspired many women to seek early screenings for the disease. Video provided by Newsy
Powered by NewsLook.com
The Cost of Ebola

The Cost of Ebola

Reuters - Business Video Online (Sep. 18, 2014) As Sierra Leone prepares for a three-day "lockdown" in its latest bid to stem the spread of Ebola, Ciara Lee looks at the financial implications of fighting the largest ever outbreak of the disease. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins