Featured Research

from universities, journals, and other organizations

Preimplantation Genetic Diagnosis Okay For Test-tube Babies, Study Finds

Date:
June 18, 2007
Source:
European Society of Human Genetics
Summary:
Children born after embryo biopsy for preimplantation genetic diagnosis do not show any more major malformations than those born after artificial reproduction technologies without PGD.

Children born after embryo biopsy for preimplantation genetic diagnosis (PGD) do not show any more major malformations than those born after artificial reproduction technologies (ART) without PGD, a scientist will tell the annual conference of the European Society of Human Genetics today. Professor Ingeborg Liebaers, from the Research Centre for Reproductive Genetics, Free University of Brussels, Brussels, Belgium, will say that the results of her study of 583 children born after PGD was reassuring.

PGD is a new option for couples at risk of transmitting genetic diseases. Instead of carrying out a prenatal diagnosis followed by a termination of pregnancy, in vitro fertilisation (IVF) with intracytoplasmic sperm injection (where a sperm is injected directly into an egg) is performed, followed by genetic testing of the embryos. Only unaffected embryos are subsequently transferred to the womb.

"Because embryos are biopsied in PGD procedures, and this constitutes an additional manipulation of a delicate organism, we set out to study whether this had any effect on the health of children who were born as a result of this procedure", says Professor Liebaers. The scientists first collected data on the pregnancies by giving questionnaires to patients on the day of the embryo transfer. Additional questionnaires were sent during pregnancy, at delivery, and later on to the patients, their gynaecologists, and paediatricians. Children were examined at 2 months and 2 years old.

"After embryo transfer, 563 children of the 583 were liveborn, 20 were stillborn, and 9 died neonatally. It seems that the perinatal death rate is higher, especially in multiple pregnancies, then in IVF and ICSi children. We need to further investigate these perinatal death rates," says Professor Liebaers, "but we were encouraged to find that the major malformation rate was only 3.6%, or no higher than that which is found in children born after conventional IVF and ICSI."

The average length of the pregnancies of singleton births was 38.8 weeks and the mean birthweight 3.268 kg, comparable to those of IVF and ICSI children, she says.

"The study is the first of a large series of PGD children from one centre", Professor Liebaers will tell the conference, "and we will be carrying out further follow-up as these children grow older. But we feel that results to date are reassuring; it is good to know that a procedure that can offer patients hope of having a baby unaffected by serious disease is also safe in the longer-term."


Story Source:

The above story is based on materials provided by European Society of Human Genetics. Note: Materials may be edited for content and length.


Cite This Page:

European Society of Human Genetics. "Preimplantation Genetic Diagnosis Okay For Test-tube Babies, Study Finds." ScienceDaily. ScienceDaily, 18 June 2007. <www.sciencedaily.com/releases/2007/06/070616191628.htm>.
European Society of Human Genetics. (2007, June 18). Preimplantation Genetic Diagnosis Okay For Test-tube Babies, Study Finds. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2007/06/070616191628.htm
European Society of Human Genetics. "Preimplantation Genetic Diagnosis Okay For Test-tube Babies, Study Finds." ScienceDaily. www.sciencedaily.com/releases/2007/06/070616191628.htm (accessed August 1, 2014).

Share This




More Health & Medicine News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Quintuplets Head Home

Texas Quintuplets Head Home

Reuters - US Online Video (Aug. 1, 2014) After four months in the hospital, the first quintuplets to be born at Baylor University Medical Center head home. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Patient Coming to U.S. for Treatment

Ebola Patient Coming to U.S. for Treatment

Reuters - US Online Video (Aug. 1, 2014) A U.S. aid worker infected with Ebola while working in West Africa will be treated in a high security ward at Emory University in Atlanta. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Vaccine Might Be Coming, But Where's It Been?

Ebola Vaccine Might Be Coming, But Where's It Been?

Newsy (Aug. 1, 2014) Health officials are working to fast-track a vaccine — the West-African Ebola outbreak has killed more than 700. But why didn't we already have one? Video provided by Newsy
Powered by NewsLook.com
Study Links Certain Birth Control Pills To Breast Cancer

Study Links Certain Birth Control Pills To Breast Cancer

Newsy (Aug. 1, 2014) Previous studies have made the link between birth control and breast cancer, but the latest makes the link to high-estrogen oral contraceptives. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins