Featured Research

from universities, journals, and other organizations

It's In Their Genes: Study Of Twins Connects Smoking Addiction With Major Depression

Date:
July 16, 2007
Source:
Saint Louis University
Summary:
Saint Louis University researcher finds genetic link between smoking, depression and conduct disorder.

Ever wonder why smoking and depression seem to go together" A Saint Louis University School of Public Health researcher finds the connection is genetic.

Related Articles


"Some people with a history of depression may become smokers as a way of self-medicating," said Qiang John Fu, M.D., Ph.D., assistant professor of community health in biostatistics at Saint Louis University School of Public Health. "Some people who are smokers might become depressed when they try to give up cigarettes and can't.

"When I tried to find something to explain this correlation, I discovered the answer lay partly in a person's genes that are associated with conduct disorder, which is extreme rebellious behavior of teens and children," Dr. Fu continued. "My findings are an alternate explanation about why nicotine dependence and major depression go together."

Dr. Fu also found that the genes that increased a person's risk of developing major depression and nicotine addiction are found in those who have conduct disorder, such as stealing, vandalizing, running away from home and fighting. These people are likely to become addicted to other drugs and behave impulsively, he said.

Dr. Fu and his team analyzed 3,360 pairs of middle-aged, predominantly Caucasian twins who served in the military during the Vietnam War.

Slightly more than half were identical twins who had a 100-percent genetic match and about 45 percent were fraternal twins who shared half their genes. Researchers compared the answers from the twins, and used a mathematical model to estimate the genetic and environmental influences on nicotine addiction and major depression.

"Our data showed that both major depression and nicotine dependence were highly genetically correlated with conduct disorder," Dr. Fu said.

The research also helps to explain why smoking seems to run in some families, Dr. Fu said.

"Maybe Dad and Mom have a certain personality, which is why they may be more likely to smoke or to be depressed. That personality trait may be based in their genes," he said.

The research points geneticists in a new direction to determine the influences of a personality trait, Dr. Fu said. In addition, clinicians could use his findings to identify those who are at risk of developing major depression or nicotine addiction.

"When they see people with a history of conduct disorder, they may be able to predict those people who could develop major depression or nicotine dependence," Dr. Fu said.

The research was funded by grants from the National Institutes of Health. It appeared in the June issue of Twin Research and Human Genetics.


Story Source:

The above story is based on materials provided by Saint Louis University. Note: Materials may be edited for content and length.


Cite This Page:

Saint Louis University. "It's In Their Genes: Study Of Twins Connects Smoking Addiction With Major Depression." ScienceDaily. ScienceDaily, 16 July 2007. <www.sciencedaily.com/releases/2007/07/070716132424.htm>.
Saint Louis University. (2007, July 16). It's In Their Genes: Study Of Twins Connects Smoking Addiction With Major Depression. ScienceDaily. Retrieved December 21, 2014 from www.sciencedaily.com/releases/2007/07/070716132424.htm
Saint Louis University. "It's In Their Genes: Study Of Twins Connects Smoking Addiction With Major Depression." ScienceDaily. www.sciencedaily.com/releases/2007/07/070716132424.htm (accessed December 21, 2014).

Share This


More From ScienceDaily



More Mind & Brain News

Sunday, December 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Buzz60 (Dec. 19, 2014) A double-amputee makes history by becoming the first person to wear and operate two prosthetic arms using only his mind. Jen Markham has the story. Video provided by Buzz60
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com
Yoga Could Be As Beneficial For The Heart As Walking, Biking

Yoga Could Be As Beneficial For The Heart As Walking, Biking

Newsy (Dec. 17, 2014) Yoga can help your weight, blood pressure, cholesterol and heart just as much as biking and walking does, a new study suggests. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins