Featured Research

from universities, journals, and other organizations

Spot On Treatment For Acne

Date:
August 15, 2007
Source:
Society of Chemical Industry
Summary:
A previously unknown side effect of an unnamed drug currently on the marketplace could be useful for treating acne. A UK company is about to start a Phase 1 trial with the drug. In an earlier phase 1 study in nine healthy human volunteers, the treatment was seen to reduce the excretion of sebum by the skin, which is associated with acne development, by up to 70 percent.

A previously unknown side effect of an unnamed drug currently on the marketplace could be useful for treating acne, reports Chemistry & Industry, the magazine of the SCI. A UK company is about to start a Phase 1 trial with the drug involving 18 healthy human volunteers and the results are expected to be announced later this year. In an earlier Phase 1 study in nine healthy human volunteers, the treatment was seen to reduce the excretion of sebum by the skin, which is associated with acne development, by up to 70%.

Related Articles


'The Phase I results are startlingly good,' said Nigel Blackburn, director of clinical development at the company, Summit, which is organising the trial. 'Reducing sebum production has been the "holy grail" of acne treatment for 30 years, and there has been little success aside from Roaccutane which has significant side effects.'

The current 'gold standard' for acne treatment, Roaccutane can cause a wide range of side effects, including teratogenicity -- which leads to abonormalities in the unborn foetus of pregnant women, and has also recently been linked to depression and (inconclusively) to teenage suicides. The market for acne treatments is worth several billion dollars, and any new treatment developed without side effects could potentially reap blockbuster sales.

Although Summit has not disclosed the name of the drug now under evaluation, the company says it represents an entirely new class of compounds for treating acne. 'At the doses we are looking at any side effects should be mild compared with those resulting from Roaccutane treatment,' Blackburn commented.

The company hopes to begin critical Phase 2 trials to assess the efficacy of the drug in acne sufferers next year. Depending on the results, the drug could either be formulated as a stand-alone topical treatment or more likely in combination with other existing treatments. The company has already been in talks with several interested companies, who are waiting to see whether the initial results can be repeated in a larger study group.

About acne

Acne develops when too much sebum is produced in the skin and the sebaceous glands are infected by the bacterium Propionibacterium acnes. The condition affects up to 80-90% of adolescents, and approximately 30% of people continue with their acne into adult life, according to the UK Primary Care Dermatology Society. The incidence of acne at age 40 is reported to be 1% in men and 5% in women.


Story Source:

The above story is based on materials provided by Society of Chemical Industry. Note: Materials may be edited for content and length.


Cite This Page:

Society of Chemical Industry. "Spot On Treatment For Acne." ScienceDaily. ScienceDaily, 15 August 2007. <www.sciencedaily.com/releases/2007/08/070813083053.htm>.
Society of Chemical Industry. (2007, August 15). Spot On Treatment For Acne. ScienceDaily. Retrieved November 23, 2014 from www.sciencedaily.com/releases/2007/08/070813083053.htm
Society of Chemical Industry. "Spot On Treatment For Acne." ScienceDaily. www.sciencedaily.com/releases/2007/08/070813083053.htm (accessed November 23, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, November 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com
WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins