Featured Research

from universities, journals, and other organizations

Gene May Hinder Spread Of Prostate Cancer

Date:
August 29, 2007
Source:
Journal of the National Cancer Institute
Summary:
Researchers have identified a gene, known as OGR1, that suppresses prostate cancer metastasis in mice. Cancer deaths are largely attributed to tumor metastasis--when the cancer cells spread to other parts of the body--rather than primary tumors. Previous research has shown that OGR1 is expressed at lower levels in metastases than in primary prostate tumors.

Researchers have identified a gene, known as OGR1, that suppresses prostate cancer metastasis in mice.

Cancer deaths are largely attributed to tumor metastasis--when the cancer cells spread to other parts of the body--rather than primary tumors. Previous research has shown that OGR1 is expressed at lower levels in metastases than in primary prostate tumors.

Lisam Shanjukumar Singh, Ph.D., of Indiana University in Indianapolis and colleagues showed that prostate cancer cells that overexpress OGR1 formed fewer metastases in mice and migrated more slowly in laboratory tests.

"Our results show that OGR1 suppresses prostate cancer metastasis without affecting the primary tumor progression, suggesting that OGR1 is a novel metastasis suppressor gene for prostate cancer," the authors write.

This research was published in the Journal of the National Cancer Institute.


Story Source:

The above story is based on materials provided by Journal of the National Cancer Institute. Note: Materials may be edited for content and length.


Cite This Page:

Journal of the National Cancer Institute. "Gene May Hinder Spread Of Prostate Cancer." ScienceDaily. ScienceDaily, 29 August 2007. <www.sciencedaily.com/releases/2007/08/070828180755.htm>.
Journal of the National Cancer Institute. (2007, August 29). Gene May Hinder Spread Of Prostate Cancer. ScienceDaily. Retrieved August 21, 2014 from www.sciencedaily.com/releases/2007/08/070828180755.htm
Journal of the National Cancer Institute. "Gene May Hinder Spread Of Prostate Cancer." ScienceDaily. www.sciencedaily.com/releases/2007/08/070828180755.htm (accessed August 21, 2014).

Share This




More Health & Medicine News

Thursday, August 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Possible Ebola Patient in Isolation at California Hospital

Possible Ebola Patient in Isolation at California Hospital

Reuters - US Online Video (Aug. 20, 2014) — A patient who may have been exposed to the Ebola virus is in isolation at the Kaiser Permanente South Sacramento Medical Center. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Raw: World's Oldest Man Lives in Japan

Raw: World's Oldest Man Lives in Japan

AP (Aug. 20, 2014) — A 111-year-old Japanese was certified as the world's oldest man by Guinness World Records on Wednesday. Sakari Momoi, a native of Fukushima in northern Japan, was given a certificate at a hospital in Tokyo. (Aug. 20) Video provided by AP
Powered by NewsLook.com
Do More Wedding Guests Make A Happier Marriage?

Do More Wedding Guests Make A Happier Marriage?

Newsy (Aug. 20, 2014) — A new study found couples who had at least 150 guests at their weddings were more likely to report being happy in their marriages. Video provided by Newsy
Powered by NewsLook.com
Ebola-Hit Sierra Leone's Freetown a City on Edge

Ebola-Hit Sierra Leone's Freetown a City on Edge

AFP (Aug. 19, 2014) — Residents of Sierra Leone's capital voice their fears as the Ebola virus sweeps through west Africa. Duration: 00:56 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins