Featured Research

from universities, journals, and other organizations

Gene May Hinder Spread Of Prostate Cancer

Date:
August 29, 2007
Source:
Journal of the National Cancer Institute
Summary:
Researchers have identified a gene, known as OGR1, that suppresses prostate cancer metastasis in mice. Cancer deaths are largely attributed to tumor metastasis--when the cancer cells spread to other parts of the body--rather than primary tumors. Previous research has shown that OGR1 is expressed at lower levels in metastases than in primary prostate tumors.

Researchers have identified a gene, known as OGR1, that suppresses prostate cancer metastasis in mice.

Related Articles


Cancer deaths are largely attributed to tumor metastasis--when the cancer cells spread to other parts of the body--rather than primary tumors. Previous research has shown that OGR1 is expressed at lower levels in metastases than in primary prostate tumors.

Lisam Shanjukumar Singh, Ph.D., of Indiana University in Indianapolis and colleagues showed that prostate cancer cells that overexpress OGR1 formed fewer metastases in mice and migrated more slowly in laboratory tests.

"Our results show that OGR1 suppresses prostate cancer metastasis without affecting the primary tumor progression, suggesting that OGR1 is a novel metastasis suppressor gene for prostate cancer," the authors write.

This research was published in the Journal of the National Cancer Institute.


Story Source:

The above story is based on materials provided by Journal of the National Cancer Institute. Note: Materials may be edited for content and length.


Cite This Page:

Journal of the National Cancer Institute. "Gene May Hinder Spread Of Prostate Cancer." ScienceDaily. ScienceDaily, 29 August 2007. <www.sciencedaily.com/releases/2007/08/070828180755.htm>.
Journal of the National Cancer Institute. (2007, August 29). Gene May Hinder Spread Of Prostate Cancer. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2007/08/070828180755.htm
Journal of the National Cancer Institute. "Gene May Hinder Spread Of Prostate Cancer." ScienceDaily. www.sciencedaily.com/releases/2007/08/070828180755.htm (accessed October 24, 2014).

Share This



More Health & Medicine News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Breakfast Debate: To Eat Or Not To Eat?

Breakfast Debate: To Eat Or Not To Eat?

Newsy (Oct. 23, 2014) Conflicting studies published in the same week re-ignited the debate over whether we should be eating breakfast. Video provided by Newsy
Powered by NewsLook.com
Ebola Fears Keep Guinea Hospitals Empty

Ebola Fears Keep Guinea Hospitals Empty

AP (Oct. 23, 2014) Fears of Ebola are keeping doctors and patients alike away from hospitals in the West African nation of Guinea. (Oct. 23) Video provided by AP
Powered by NewsLook.com
Despite Rising Death Toll, Many Survive Ebola

Despite Rising Death Toll, Many Survive Ebola

AP (Oct. 23, 2014) The family of a Dallas nurse infected with Ebola in the US says doctors can no longer detect the virus in her. Despite the mounting death toll in West Africa, there are survivors there too. (Oct. 23) Video provided by AP
Powered by NewsLook.com
Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Working Mother (Oct. 22, 2014) Is your child ready? Video provided by Working Mother
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins