Featured Research

from universities, journals, and other organizations

New Treatment For Stroke Works Up To A Day After Symptoms Start

Date:
October 5, 2007
Source:
American Academy of Neurology
Summary:
People treated with the drug minocycline within six to 24 hours after a stroke had significantly fewer disabilities, according to a new study. Researchers say minocycline may be an alternative treatment for stroke because current treatments only work during the first few hours after the onset of symptoms, and many people don't get to the hospital in time to be treated.

People treated with the drug minocycline within six to 24 hours after a stroke had significantly fewer disabilities, according to a study published in the October 2, 2007, issue of Neurology®, the medical journal of the American Academy of Neurology.

Researchers say minocycline may be an alternative treatment for stroke because current treatments only work during the first few hours after the onset of symptoms, and many people don't get to the hospital in time to be treated.

For the study, 152 men and women received either an oral dose of minocycline or placebo for five days following stroke. People who received minocycline were treated an average of 13 hours after stroke compared to 12 hours for the placebo group. Researchers followed both groups for three months.

The study found people treated with minocycline had significantly better outcomes than those treated with placebo. After three months, the minocycline group performed four times better than the placebo group on the National Institutes of Health Stroke Scale, which measures vision, facial palsy, movement, and speaking ability. The minocycline group received a score of 1.6, which indicates little or no disability, compared to a score of 6.5 for the placebo group, which indicates a high end of mild disability.

"The improvement was already apparent within a week of the stroke," said study author Yair Lampl, MD, with Edith Wolfson Medical Center and Tel Aviv University in Israel. "This is exciting because many people who have had stroke cannot be treated if they don't get to the hospital within three hours after symptoms start, which is the time frame for current available treatments."

"While these are promising results, a much larger, closed-label, study is needed to confirm our findings," said Lampl. "Further research is also needed to look at whether the dosage of the drug taken in this study is optimal and whether giving the drug through an IV would be more effective."

Lampl says the improvement shown by patients taking minocycline is not due to the drug's basic antibiotic effect, but rather its anti-inflammatory effect and ability to protect brain cells from destruction. Minocycline has already been shown in other studies to have a neuroprotective effect in animal models of multiple sclerosis, Parkinson's disease, Huntington's disease, and Lou Gehrig's disease, or ALS.

Lampl says none of the participants experienced any serious side effects from the drug.

.


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Neurology. "New Treatment For Stroke Works Up To A Day After Symptoms Start." ScienceDaily. ScienceDaily, 5 October 2007. <www.sciencedaily.com/releases/2007/10/071001172858.htm>.
American Academy of Neurology. (2007, October 5). New Treatment For Stroke Works Up To A Day After Symptoms Start. ScienceDaily. Retrieved September 23, 2014 from www.sciencedaily.com/releases/2007/10/071001172858.htm
American Academy of Neurology. "New Treatment For Stroke Works Up To A Day After Symptoms Start." ScienceDaily. www.sciencedaily.com/releases/2007/10/071001172858.htm (accessed September 23, 2014).

Share This



More Mind & Brain News

Tuesday, September 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) — The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Food Addiction Might Be Caused By PTSD

Food Addiction Might Be Caused By PTSD

Newsy (Sep. 18, 2014) — New research shows that women who suffer from PTSD are three times more likely to develop a food addiction. Video provided by Newsy
Powered by NewsLook.com
Corporal Punishment on Decline, Debate Renews

Corporal Punishment on Decline, Debate Renews

AP (Sep. 16, 2014) — Corporal punishment in the United States is on the decline, but there is renewed debate over its use after Minnesota Vikings running back Adrian Peterson was charged with child abuse. (Sept. 16) Video provided by AP
Powered by NewsLook.com
FDA Eyes Skin Shocks Used at Mass. School

FDA Eyes Skin Shocks Used at Mass. School

AP (Sep. 15, 2014) — The FDA is considering whether to ban devices used by the Judge Rotenberg Educational Center in Canton, Massachusetts, the only place in the country known to use electrical skin shocks as aversive conditioning for aggressive patients. (Sept. 15) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins