Featured Research

from universities, journals, and other organizations

Freezing Bone Cancer Tumors Reduces Pain, Study Shows

Date:
November 28, 2007
Source:
Mayo Clinic
Summary:
Cryoablation, a procedure most commonly associated with destroying kidney and prostate tumors by freezing them, has been shown to offer durable pain relief of cancer that has spread to bone.

Cryoablation, a procedure most commonly associated with destroying kidney and prostate tumors by freezing them, has been shown to offer durable pain relief of cancer that has spread to bone. The procedure freezes and shrinks or destroys cancerous tumors in or near bone.

Related Articles


"Cancer patients are living longer and we need to be able to manage their pain over a long period of time," says Matthew Callstrom, M.D., Ph.D., a radiologist at Mayo Clinic who will present his latest findings on cryoablation for pain management at the Radiological Society of North America annual meeting the week of Nov. 27.

Each year in the United States approximately 100,000 people develop cancer that spreads to the bone (metastasizes). This type of cancer causes extreme pain and often cannot be managed by narcotics or other standard treatments. New approaches in pain management are needed to help patients living longer with cancer, achieve a higher quality of life.

In this study, cryoablation was used to treat 34 patients whose primary cancers had spread to the bone. These patients either did not have success with conventional pain management treatments or refused such treatments. Eighty percent of the patients experienced a clinically significant reduction in pain. Furthermore, the treatment appears to have lasting effects: 24 weeks after undergoing the procedure, patients still reported significantly lower levels of pain.

"Two key parts of this study are that the reduction in pain lasts and their quality of life improves after receiving the treatment," Dr. Callstrom says.

These results are important for two reasons: first, cryoablation worked after other treatments failed to provide adequate pain relief; second, cryoablation provides long-term pain relief. Radiation therapy, which is considered the gold standard in pain management for patients with focal pain associated with metastatic cancer, provides only short-term relief for many patients, he states.

Dr. Callstrom recently received a $900,000 grant from the National Cancer Institute to lead a nationwide study to compare cryoablation and radiation therapy as treatment for pain associated with metastatic cancer. This will be a randomized study in which patients will receive either cryoablation or radiation therapy.

Cryoablation is a more precise treatment as compared to radiation therapy. Doctors use imaging tools, such as CT, to guide small needle-like probes into the tumor. Gas is then circulated through the probes, supercooling the tumor and turning it into a ball of ice.

The procedure calls for a probe inserted directly into the tumor with ultrasound or CT imaging guiding the way. It is a minimally invasive procedure in which only a inch long cut is required to insert the probe. Patients are usually sedated for the procedure and released 24 hours later. The recovery time is short and patients typically start experiencing pain relief within a few days to four weeks after treatment.

Patients in this study had primary cancers that included colorectal, renal cell, bronchogenic, squamous cell, adrenal cortical, ovarian and thyroid carcinomas, paragangliomas (tumors that arise within the sympathetic nervous system), melanoma and desmoid tumors (tumors of tissue that surrounds muscles).

This study is funded by Endocare Inc.


Story Source:

The above story is based on materials provided by Mayo Clinic. Note: Materials may be edited for content and length.


Cite This Page:

Mayo Clinic. "Freezing Bone Cancer Tumors Reduces Pain, Study Shows." ScienceDaily. ScienceDaily, 28 November 2007. <www.sciencedaily.com/releases/2007/11/071127212218.htm>.
Mayo Clinic. (2007, November 28). Freezing Bone Cancer Tumors Reduces Pain, Study Shows. ScienceDaily. Retrieved November 23, 2014 from www.sciencedaily.com/releases/2007/11/071127212218.htm
Mayo Clinic. "Freezing Bone Cancer Tumors Reduces Pain, Study Shows." ScienceDaily. www.sciencedaily.com/releases/2007/11/071127212218.htm (accessed November 23, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, November 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com
WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins