Featured Research

from universities, journals, and other organizations

Cholesterol-lowering Drugs May Not Prevent Alzheimer's Disease, According To New Study

Date:
January 17, 2008
Source:
American Academy of Neurology
Summary:
Contrary to some reports, taking statins, which are cholesterol-lowering drugs, offers no protection against Alzheimer's disease, according to new research. The study involved 929 Catholic clergy members who were an average of 75 years old, free of dementia at the beginning of the study and enrolled in the Religious Orders Study, an ongoing study of aging and Alzheimer's disease. All of the participants agreed to a brain autopsy at the time of their death and underwent annual cognitive tests for up to 12 years.

Contrary to some reports, taking statins, which are cholesterol-lowering drugs, offers no protection against Alzheimer's disease, according to new research.

The study involved 929 Catholic clergy members who were an average of 75 years old, free of dementia at the beginning of the study and enrolled in the Religious Orders Study, an ongoing study of aging and Alzheimer's disease. All of the participants agreed to a brain autopsy at the time of their death and underwent annual cognitive tests for up to 12 years.

At the beginning of the study, 119 people were taking a statin. During the 12-year follow-up period, 191 people developed Alzheimer's disease, of whom 16 used statins at the start of the study.

"Some studies have suggested people taking cholesterol-lowering drugs are less likely to have Alzheimer's disease, but our longitudinal findings found no relation between statin use and Alzheimer's," said study author Zoe Arvanitakis, MD, MS, Associate Professor of the Department of Neurological Sciences at Rush University Medical Center in Chicago and member of the American Academy of Neurology. "The study also found no association between taking statins and a slower cognitive decline among older people."

In addition, researchers performed brain autopsies on more than 250 people who died during the study to examine the relation of statins to Alzheimer's disease pathology and stroke in the brain, the two common pathological causes of dementia. The study found statin use at any time during the course of the study had no effect on pathology of Alzheimer's disease or strokes.

Arvanitakis says the study is limited in that there were relatively few statin users among those who died. She says future studies will need to look at the possibility of associations of statins with other pathologic changes of Alzheimer's disease not examined in this study.

published in the January 16, 2008, online issue of Neurology®, the medical journal of the American Academy of Neurology.

The study was supported by grants from the National Institute on Aging.


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Neurology. "Cholesterol-lowering Drugs May Not Prevent Alzheimer's Disease, According To New Study." ScienceDaily. ScienceDaily, 17 January 2008. <www.sciencedaily.com/releases/2008/01/080116164255.htm>.
American Academy of Neurology. (2008, January 17). Cholesterol-lowering Drugs May Not Prevent Alzheimer's Disease, According To New Study. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2008/01/080116164255.htm
American Academy of Neurology. "Cholesterol-lowering Drugs May Not Prevent Alzheimer's Disease, According To New Study." ScienceDaily. www.sciencedaily.com/releases/2008/01/080116164255.htm (accessed August 1, 2014).

Share This




More Health & Medicine News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Quintuplets Head Home

Texas Quintuplets Head Home

Reuters - US Online Video (Aug. 1, 2014) — After four months in the hospital, the first quintuplets to be born at Baylor University Medical Center head home. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Patient Coming to U.S. for Treatment

Ebola Patient Coming to U.S. for Treatment

Reuters - US Online Video (Aug. 1, 2014) — A U.S. aid worker infected with Ebola while working in West Africa will be treated in a high security ward at Emory University in Atlanta. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Vaccine Might Be Coming, But Where's It Been?

Ebola Vaccine Might Be Coming, But Where's It Been?

Newsy (Aug. 1, 2014) — Health officials are working to fast-track a vaccine — the West-African Ebola outbreak has killed more than 700. But why didn't we already have one? Video provided by Newsy
Powered by NewsLook.com
Study Links Certain Birth Control Pills To Breast Cancer

Study Links Certain Birth Control Pills To Breast Cancer

Newsy (Aug. 1, 2014) — Previous studies have made the link between birth control and breast cancer, but the latest makes the link to high-estrogen oral contraceptives. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins