Featured Research

from universities, journals, and other organizations

Cholesterol-lowering Drugs May Not Prevent Alzheimer's Disease, According To New Study

Date:
January 17, 2008
Source:
American Academy of Neurology
Summary:
Contrary to some reports, taking statins, which are cholesterol-lowering drugs, offers no protection against Alzheimer's disease, according to new research. The study involved 929 Catholic clergy members who were an average of 75 years old, free of dementia at the beginning of the study and enrolled in the Religious Orders Study, an ongoing study of aging and Alzheimer's disease. All of the participants agreed to a brain autopsy at the time of their death and underwent annual cognitive tests for up to 12 years.

Contrary to some reports, taking statins, which are cholesterol-lowering drugs, offers no protection against Alzheimer's disease, according to new research.

The study involved 929 Catholic clergy members who were an average of 75 years old, free of dementia at the beginning of the study and enrolled in the Religious Orders Study, an ongoing study of aging and Alzheimer's disease. All of the participants agreed to a brain autopsy at the time of their death and underwent annual cognitive tests for up to 12 years.

At the beginning of the study, 119 people were taking a statin. During the 12-year follow-up period, 191 people developed Alzheimer's disease, of whom 16 used statins at the start of the study.

"Some studies have suggested people taking cholesterol-lowering drugs are less likely to have Alzheimer's disease, but our longitudinal findings found no relation between statin use and Alzheimer's," said study author Zoe Arvanitakis, MD, MS, Associate Professor of the Department of Neurological Sciences at Rush University Medical Center in Chicago and member of the American Academy of Neurology. "The study also found no association between taking statins and a slower cognitive decline among older people."

In addition, researchers performed brain autopsies on more than 250 people who died during the study to examine the relation of statins to Alzheimer's disease pathology and stroke in the brain, the two common pathological causes of dementia. The study found statin use at any time during the course of the study had no effect on pathology of Alzheimer's disease or strokes.

Arvanitakis says the study is limited in that there were relatively few statin users among those who died. She says future studies will need to look at the possibility of associations of statins with other pathologic changes of Alzheimer's disease not examined in this study.

published in the January 16, 2008, online issue of Neurology®, the medical journal of the American Academy of Neurology.

The study was supported by grants from the National Institute on Aging.


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Neurology. "Cholesterol-lowering Drugs May Not Prevent Alzheimer's Disease, According To New Study." ScienceDaily. ScienceDaily, 17 January 2008. <www.sciencedaily.com/releases/2008/01/080116164255.htm>.
American Academy of Neurology. (2008, January 17). Cholesterol-lowering Drugs May Not Prevent Alzheimer's Disease, According To New Study. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2008/01/080116164255.htm
American Academy of Neurology. "Cholesterol-lowering Drugs May Not Prevent Alzheimer's Disease, According To New Study." ScienceDaily. www.sciencedaily.com/releases/2008/01/080116164255.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) — Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Concern Grows Over Worsening Ebola Crisis

Concern Grows Over Worsening Ebola Crisis

AFP (July 30, 2014) — Pan-African airline ASKY has suspended all flights to and from the capitals of Liberia and Sierra Leone amid the worsening Ebola health crisis, which has so far caused 672 deaths in Guinea, Liberia and Sierra Leone. Duration: 00:43 Video provided by AFP
Powered by NewsLook.com
At Least 20 Chikungunya Cases in New Jersey

At Least 20 Chikungunya Cases in New Jersey

AP (July 30, 2014) — At least 20 New Jersey residents have tested positive for chikungunya, a mosquito-borne virus that has spread through the Caribbean. (July 30) Video provided by AP
Powered by NewsLook.com
Xtreme Eating: Your Daily Caloric Intake All On One Plate

Xtreme Eating: Your Daily Caloric Intake All On One Plate

Newsy (July 30, 2014) — The Center for Science in the Public Interest released its 2014 list of single meals with whopping calorie counts. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



      Save/Print:
      Share:  

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile iPhone Android Web
      Follow Facebook Twitter Google+
      Subscribe RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins