Featured Research

from universities, journals, and other organizations

Folate Deficiency Associated With Tripling Of Dementia Risk, Study Shows

Date:
February 5, 2008
Source:
BMJ-British Medical Journal
Summary:
Folate deficiency is associated with a tripling in the risk of developing dementia among elderly people, suggests new research. The onset of dementia was significantly more likely in those whose folate levels then fell further over the two years, while their homocysteine levels rose. People who were folate deficient to begin with, were almost 3.5 times more likely to develop dementia.

Folate deficiency is associated with a tripling in the risk of developing dementia among elderly people, suggests research published ahead of print in the Journal of Neurology Neurosurgery and Psychiatry.

Related Articles


The researchers tracked the development of dementia in 518 people over two years from 2001 to 2003. All participants were over the age of 65 and lived in one rural and one urban area in the south of the country.

Validated tests were carried out at the start and end of the two year period to find out if they had a dementing illness. Similarly, blood tests were taken to assess levels of folate, vitamin B12, and the protein homocysteine, and how these changed over time.

High levels of homocysteine have been associated with cardiovascular disease.

At the start of the two year period, almost one in five people had high levels of homocysteine, while 17% had low vitamin B12 levels and 3.5% were folate deficient.

The higher the levels of folate to begin with, the higher were vitamin B12 levels, and the lower those of homocysteine.

By the end of the study, 45 people had developed dementia. Of these, 34 had Alzheimer's disease, seven had vascular dementia, and four had "other" types of dementia.

Dementia was more likely in those who were older, relatively poorly educated, inactive, and had deposits of the protein ApoE.

The onset of dementia was significantly more likely in those whose folate levels then fell further over the two years, while their homocysteine levels rose. People who were folate deficient to begin with, were almost 3.5 times more likely to develop dementia.

The authors suggest that changes in micronutrients could be linked with the other typical signs that precede dementia, including weight loss and low blood pressure.

While weight loss is unlikely to alter micronutrients levels in the blood, it may indicate dietary changes in the quality of quantity of food intake.


Story Source:

The above story is based on materials provided by BMJ-British Medical Journal. Note: Materials may be edited for content and length.


Cite This Page:

BMJ-British Medical Journal. "Folate Deficiency Associated With Tripling Of Dementia Risk, Study Shows." ScienceDaily. ScienceDaily, 5 February 2008. <www.sciencedaily.com/releases/2008/02/080204212850.htm>.
BMJ-British Medical Journal. (2008, February 5). Folate Deficiency Associated With Tripling Of Dementia Risk, Study Shows. ScienceDaily. Retrieved February 27, 2015 from www.sciencedaily.com/releases/2008/02/080204212850.htm
BMJ-British Medical Journal. "Folate Deficiency Associated With Tripling Of Dementia Risk, Study Shows." ScienceDaily. www.sciencedaily.com/releases/2008/02/080204212850.htm (accessed February 27, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, February 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Reuters - Innovations Video Online (Feb. 27, 2015) A dongle that plugs into a Smartphone mimics a lab-based blood test for HIV and syphilis and can detect the diseases in 15 minutes, say researchers. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com
Doctor Says Head Transplants Possible Within Two Years

Doctor Says Head Transplants Possible Within Two Years

Buzz60 (Feb. 27, 2015) An Italian doctor is saying he could stick someone&apos;s head onto someone else&apos;s body. Patrick Jones (@Patrick_E_Jones) reports. Video provided by Buzz60
Powered by NewsLook.com
How Your Dentist Could Help Screen You For Diabetes

How Your Dentist Could Help Screen You For Diabetes

Newsy (Feb. 27, 2015) A new study from researchers at New York University suggests dentists could soon use blood samples taken from patients&apos; mouths to test for diabetes. Video provided by Newsy
Powered by NewsLook.com
The Best Tips to Makeover Your Health

The Best Tips to Makeover Your Health

Buzz60 (Feb. 27, 2015) If you&apos;re looking to boost your health this season, there are a few quick and easy steps to prompt you for success. Krystin Goodwin (@Krystingoodwin) has the best tips to give your health a makeover this spring! Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins