Featured Research

from universities, journals, and other organizations

From Stem Cells To Organs: The Bioengineering Challenge

Date:
February 17, 2008
Source:
Natural Sciences and Engineering Research Council
Summary:
Scientists have been making great strides in revving up the production of stem cells and their descendants. The raw materials are adult blood stem cells and embryonic stem cells. The end products are blood and heart cells -- lots of them. Enough mouse heart cells that they form beating tissue.

For more than a decade, Peter Zandstra has been working at the University of Toronto to rev up the production of stem cells and their descendants. The raw materials are adult blood stem cells and embryonic stem cells. The end products are blood and heart cells -- lots of them. Enough mouse heart cells that they form beating tissue.

To do this, he has been applying engineering principles to stem cell research. Starting with computer models of stem cell growth and differentiation (the process by which a stem cell matures into its final form), Zandstra has moved on to develop more sophisticated culture methods that fine-tune the microenvironments to guide the generation of the different cells types that make up the mature cells in our tissues: heart cells for the heart or blood cells for blood.

"If you describe something mathematically, you have a much better understanding of it than if you just observe it," he says. "And it's also a powerful way to test many different hypotheses in silico before going into the lab and doing the much more difficult experiments in vitro."

Dr. Zandstra, the Canada Research Chair in Stem Cell Bioengineering, held a NSERC Steacie Fellowship. The Steacie prize - which goes to six select Canadian professors annually -- allowed Zandstra to extend his work from mouse to man.

"There's only so much we can do with mouse cells," notes Dr. Zandstra. "Now if we can also figure out how to get human embryonic stem cells to differentiate on command to generate functional adult-like cells, you can begin to think about the kinds of medical conditions you could treat with them."

Dr Zandstra's work was discussed at the annual meeting of the American Association for the Advancement of Science in Boston from February 14 to 18, 2008.


Story Source:

The above story is based on materials provided by Natural Sciences and Engineering Research Council. Note: Materials may be edited for content and length.


Cite This Page:

Natural Sciences and Engineering Research Council. "From Stem Cells To Organs: The Bioengineering Challenge." ScienceDaily. ScienceDaily, 17 February 2008. <www.sciencedaily.com/releases/2008/02/080216095724.htm>.
Natural Sciences and Engineering Research Council. (2008, February 17). From Stem Cells To Organs: The Bioengineering Challenge. ScienceDaily. Retrieved October 1, 2014 from www.sciencedaily.com/releases/2008/02/080216095724.htm
Natural Sciences and Engineering Research Council. "From Stem Cells To Organs: The Bioengineering Challenge." ScienceDaily. www.sciencedaily.com/releases/2008/02/080216095724.htm (accessed October 1, 2014).

Share This



More Health & Medicine News

Wednesday, October 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pregnancy Spacing Could Have Big Impact On Autism Risks

Pregnancy Spacing Could Have Big Impact On Autism Risks

Newsy (Oct. 1, 2014) A new study says children born less than one year and more than five years after a sibling can have an increased risk for autism. Video provided by Newsy
Powered by NewsLook.com
Robotic Hair Restoration

Robotic Hair Restoration

Ivanhoe (Oct. 1, 2014) A new robotic procedure is changing the way we transplant hair. The ARTAS robot leaves no linear scarring and provides more natural results. Video provided by Ivanhoe
Powered by NewsLook.com
Insertable Cardiac Monitor

Insertable Cardiac Monitor

Ivanhoe (Oct. 1, 2014) A heart monitor the size of a paperclip that can save your life. The “Reveal Linq” allows a doctor to monitor patients with A-Fib on a continuous basis for up to 3 years! Video provided by Ivanhoe
Powered by NewsLook.com
Attacking Superbugs

Attacking Superbugs

Ivanhoe (Oct. 1, 2014) Two weapons hospitals can use to attack superbugs. Scientists in Ireland created a new gel resistant to superbugs, and a robot that can disinfect a room in minutes. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins