Featured Research

from universities, journals, and other organizations

Using Anti-cholinergic Drugs May Increase Cognitive Decline In Older People

Date:
April 22, 2008
Source:
American Academy of Neurology
Summary:
Anticholinergic drugs, such as medicines for stomach cramps, ulcers, motion sickness and urinary incontinence, may cause older people to experience greater decline in their thinking skills than people not taking the drugs.

Anticholinergic drugs, such as medicines for stomach cramps, ulcers, motion sickness, and urinary incontinence, may cause older people to experience greater decline in their thinking skills than people not taking the drugs, according to new research.

Related Articles


The study looked at the effects of taking a medication with anticholinergic properties on the annual change in thinking abilities of 870 Catholic nuns and clergy members who were an average of 75 years old. All of the participants were part of the Rush Religious Orders Study, an ongoing, longitudinal, clinical study of older people without dementia.

All of the participants underwent annual cognitive tests and reported their medication use for an average followup period of eight years. During the study, 679 people took at least one medication with anticholinergic properties.

The study found those people who took anticholinergic drugs saw their rate of cognitive function decline 1.5 times as fast as those people who did not take the drugs.

"Our findings point to anticholinergic drugs having an adverse impact on cognitive performance in otherwise normal, older people," said study author Jack Tsao, MD, DPhil, Associate Professor of Neurology at Uniformed Services University in Bethesda, Maryland, and member of the American Academy of Neurology. "Doctors may need to take this into account before prescribing these commonly used drugs."

Tsao says more research is needed to determine the mechanism behind the rapid memory loss apparently associated with anticholinergic drugs and to identify which drugs, in particular, may be more likely to impair cognition.

This research was presented at the American Academy of Neurology 60th Anniversary Annual Meeting in Chicago, April 17, 2008. The study was supported by the American Philosophical Society Daland Grant and grants from the National Institute on Aging.


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Neurology. "Using Anti-cholinergic Drugs May Increase Cognitive Decline In Older People." ScienceDaily. ScienceDaily, 22 April 2008. <www.sciencedaily.com/releases/2008/04/080417211539.htm>.
American Academy of Neurology. (2008, April 22). Using Anti-cholinergic Drugs May Increase Cognitive Decline In Older People. ScienceDaily. Retrieved March 6, 2015 from www.sciencedaily.com/releases/2008/04/080417211539.htm
American Academy of Neurology. "Using Anti-cholinergic Drugs May Increase Cognitive Decline In Older People." ScienceDaily. www.sciencedaily.com/releases/2008/04/080417211539.htm (accessed March 6, 2015).

Share This


More From ScienceDaily



More Mind & Brain News

Friday, March 6, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Former NFL Players Donate Brains to Science

Former NFL Players Donate Brains to Science

Reuters - US Online Video (Mar. 3, 2015) Super Bowl champions Sidney Rice and Steve Weatherford donate their brains, post-mortem, to scientific research into repetitive brain trauma. Jillian Kitchener reports. Video provided by Reuters
Powered by NewsLook.com
Alzheimer's Protein Plaque Found In 20-Year-Olds

Alzheimer's Protein Plaque Found In 20-Year-Olds

Newsy (Mar. 3, 2015) Researchers found an abnormal protein associated with Alzheimer&apos;s disease in the brains of 20-year-olds. Video provided by Newsy
Powered by NewsLook.com
This Nasal Treatment Could Help Ease Migraine Pain

This Nasal Treatment Could Help Ease Migraine Pain

Newsy (Mar. 2, 2015) Researchers gave lidocaine to 112 patients, and about 88 percent of the subjects said they needed less migraine-relief medicine the next day. Video provided by Newsy
Powered by NewsLook.com
How Facebook Use Can Lead To Depression

How Facebook Use Can Lead To Depression

Newsy (Mar. 1, 2015) Margaret Duffy of the University of Missouri talks about her study on the social network and the envy and depression that Facebook use can cause. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins