Featured Research

from universities, journals, and other organizations

External-beam Radiation Therapy For Localized Prostate Cancer Linked To Other Cancer

Date:
May 15, 2008
Source:
American Urological Association
Summary:
Patients undergoing external-beam radiation therapy for localized prostate cancer may be at an increased risk for secondary malignancy, according to a new study.

Patients undergoing external-beam radiation therapy (EBRT) for localized prostate cancer may be at an increased risk for secondary malignancy, according to a study from researchers in Canada, Italy and the United States presented during the Annual Scientific Meeting of the American Urological Association (AUA) in Orlando.

Related Articles


These findings have significant implications for men evaluating treatment options for localized prostate cancer.

Using records from 10,333 men treated for localized prostate cancer (6,196 with radical prostatectomy and 4,137 with EBRT) between 1983 and 2004, researchers examined subsequent diagnoses of bladder, lung and colorectal cancer to determine whether the incidence rate of these secondary malignancies was greater in patients who underwent EBRT as opposed to radical prostatectomy.

Researchers used diagnosis codes defining cystectomy, lobectomy or pneumectomy (for lung cancer) and colectomy (with or without rectal resection) for colorectal cancer to identify the incidence of secondary malignancy in this study population. 92 cystectomies, 82 lung cancer surgeries and 228 colorectal cancer surgeries were performed. Univariable analyses showed an increase in the rate of secondary malignancy treatment in men treated with EBRT.

Multivariate analysis was performed, with adjustments made for age, baseline comorbidities and year of treatment – and indicated that EBRT predisposed patients to a 3.0-fold increase for cystectomy for bladder cancer, 1.8-fold rate of lung-cancer resections and 1.7-fold higher rate of rectal cancer.


Story Source:

The above story is based on materials provided by American Urological Association. Note: Materials may be edited for content and length.


Journal Reference:

  1. Bhojani N, Jeldres C, Da Pozzo LF, Morgan M, Shariat S, Perrotte P et al: External-beam radiation therapy increases the rate of secondary malignancies relative to radical prostatectomy in men with prostate cancer. J Urol, suppl., 2008; 179: 113, abstract 318. [link]

Cite This Page:

American Urological Association. "External-beam Radiation Therapy For Localized Prostate Cancer Linked To Other Cancer." ScienceDaily. ScienceDaily, 15 May 2008. <www.sciencedaily.com/releases/2008/05/080515072803.htm>.
American Urological Association. (2008, May 15). External-beam Radiation Therapy For Localized Prostate Cancer Linked To Other Cancer. ScienceDaily. Retrieved April 25, 2015 from www.sciencedaily.com/releases/2008/05/080515072803.htm
American Urological Association. "External-beam Radiation Therapy For Localized Prostate Cancer Linked To Other Cancer." ScienceDaily. www.sciencedaily.com/releases/2008/05/080515072803.htm (accessed April 25, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, April 25, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

85 Killed in Niger by Meningitis Since Start of Year

85 Killed in Niger by Meningitis Since Start of Year

AFP (Apr. 24, 2015) A meningitis outbreak in Niger has killed 85 people since the start of the year prompting authorities to close schools in the capital Niamey until Monday. Video provided by AFP
Powered by NewsLook.com
C-Section Births a Trend in Brazil

C-Section Births a Trend in Brazil

AFP (Apr. 24, 2015) More than half of Brazil&apos;s babies are born via cesarean section, as mothers and doctors opt for a faster and less painful experience despite the health risks. Duration: 02:02 Video provided by AFP
Powered by NewsLook.com
Anti-Malaria Jab Hope

Anti-Malaria Jab Hope

Reuters - News Video Online (Apr. 24, 2015) The world&apos;s first anti-malaria vaccine could get the go-ahead for use in Africa from October if approved by international regulators. Paul Chapman reports. Video provided by Reuters
Powered by NewsLook.com
3D Food Printing: The Meal of the Future?

3D Food Printing: The Meal of the Future?

AP (Apr. 23, 2015) Developers of 3D food printing hope the culinary technology will revolutionize the way we cook and eat. (April 23) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins