Featured Research

from universities, journals, and other organizations

New Technology May Prevent Vitamin B12 Deficient Seniors And Vegetarians From Needing Injections

Date:
June 22, 2008
Source:
American Association of Pharmaceutical Scientists
Summary:
For those patients who receive the nearly 40 million intramuscular injections per year to treat their B12 deficiency, a new oral option may soon exist. According to the National Institutes of Health, vitamin B12 deficiency can lead to a wide spectrum of conditions, such as anemia, dementia and reduced cognitive functioning.

For those patients who receive the nearly 40 million intramuscular injections per year to treat their B12 deficiency, a new oral option may soon exist.

According to the National Institutes of Health, vitamin B12 deficiency can lead to a wide spectrum of conditions, such as anemia, dementia and reduced cognitive functioning. Vitamin B12 deficiency is a significant health issue. Nearly 40 percent of the U.S. population is B12 deficient (Tufts University, Boston). This includes a sizable number of patients who are severely deficient and are currently being treated.

Further, a vast number of people are completely unaware they are B12 deficient and will eventually need treatment. Seniors and strict vegetarians are most at risk. Symptoms such as fatigue, constipation, loss of appetite and weight loss can occur in those who are deficient.

Currently, physicians rely on B12 shots for people with vitamin B12 deficiency because of the poor bioavailability of oral formulations. Past studies have shown that only approximately one percent of a vitamin B12 tablet gets absorbed in the bloodstream after traveling through the digestive track. Because so much of the vitamin is wasted, alternatives to effectively treat or protect against B12 deficiency are needed.

"Vitamin B12 is a perfect example of the successful application of our eligenฎ technology," said Cristina Castelli, Ph. D., AAPS expert and lead researcher at Emisphere Technologies, Inc. "Our current studies have shown our oral solid formulation brings vitamin B12 absorption to a range of 7-30% without the discomfort of an invasive route of administration."

Ms. Castelli and other project researchers will be at the AAPS National Biotechnology Conference to present and discuss their research with hundreds of pharmaceutical scientists from countries around the world.

Animal testing has been completed and researchers are now conducting human studies.

 


Story Source:

The above story is based on materials provided by American Association of Pharmaceutical Scientists. Note: Materials may be edited for content and length.


Cite This Page:

American Association of Pharmaceutical Scientists. "New Technology May Prevent Vitamin B12 Deficient Seniors And Vegetarians From Needing Injections." ScienceDaily. ScienceDaily, 22 June 2008. <www.sciencedaily.com/releases/2008/06/080617104938.htm>.
American Association of Pharmaceutical Scientists. (2008, June 22). New Technology May Prevent Vitamin B12 Deficient Seniors And Vegetarians From Needing Injections. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/2008/06/080617104938.htm
American Association of Pharmaceutical Scientists. "New Technology May Prevent Vitamin B12 Deficient Seniors And Vegetarians From Needing Injections." ScienceDaily. www.sciencedaily.com/releases/2008/06/080617104938.htm (accessed April 19, 2014).

Share This



More Health & Medicine News

Saturday, April 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Nine-Month-Old Baby Can't Open His Mouth

Nine-Month-Old Baby Can't Open His Mouth

Newsy (Apr. 19, 2014) — Nine-month-old Wyatt Scott was born with a rare disorder called congenital trismus, which prevents him from opening his mouth. Video provided by Newsy
Powered by NewsLook.com
'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) — In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) — A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) — The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins