Featured Research

from universities, journals, and other organizations

Women Exposed To High Levels of Pollutant PCB More Likely To Give Birth To Female Children

Date:
July 16, 2008
Source:
BioMed Central/Environmental Health
Summary:
Women exposed to high levels of PCBs (polychlorinated biphenyls -- a group of banned environmental pollutants) are less likely to give birth to male children. A new study found that among women from the San Francisco Bay Area, those exposed to higher levels of PCBs during the 50s and 60s, were significantly more likely to give birth to female children.

Women exposed to high levels of PCBs (polychlorinated biphenyls -- a group of banned environmental pollutants) are less likely to give birth to male children. A new study found that among women from the San Francisco Bay Area, those exposed to higher levels of PCBs during the 50s and 60s, were significantly more likely to give birth to female children.

Similar exposure is thought to have occurred in Wales, after a quarry on the edge of Groesfaen village near Cardiff was used as a toxic dumping ground from 1965 to 1972.

PCBs are persistent organic pollutants identified worldwide as human blood and breast milk contaminants. They were widely used in industry as cooling and insulating fluids for electrical equipment, as well as in construction and domestic products such as varnishes and caulks. PCBs were banned in the 1970s because of their general toxicity and persistence. They are associated with effects on immune, reproductive, nervous, and endocrine systems. Given the high quality measurements, this research provides the strongest evidence to date that PCBs affect sex ratio in human children.

Irva Hertz-Picciotto, the lead author of the study, explains how marked the effect was, "The women most exposed to PCBs were 33% less likely to give birth to male children than the women least exposed". The researchers measured the levels of PCBs in blood taken from pregnant women during a Bay Area study in the 1960s. When they compared these levels to the children's sex, they found that for every one microgram of PCBs per litre of serum, the chance of having a male child fell by 7%.

As Hertz-Picciotto states, "These findings suggest that high maternal PCB concentrations may either favour fertilization by female sperm or result in greater male embryonic or fetal losses. The association could be due to contaminants, PCB metabolites or the PCBs themselves".

This investigation will be useful for assessing problems likely to be faced by populations currently exposed to high levels of PCBs, such as those that rely on fish from contaminated lakes or who live near former manufacturing facilities. Furthermore, other chemicals with a similar structure to PCBs, such as the flame-retardants PBDEs (polybrominated diphenyl ethers), are currently widely used in plastic casings and foam products. According to the authors, "PBDEs share many of the biochemical and toxicologic properties of PCBs. As levels of these substances rise in wildlife and human populations, studies like ours provide an indication of the potential effects of these newer compounds".


Story Source:

The above story is based on materials provided by BioMed Central/Environmental Health. Note: Materials may be edited for content and length.


Journal Reference:

  1. Irva Hertz-Picciotto, Todd A Jusko, M Judith Charles, Rebecca J Baker, Jean A Keller, Teri A Greenfield, Eric J Willman and Stuart W Teplin. A cohort study of in utero polychlorinated biphenyl (PCB) exposures in relation to secondary sex ratio. Environmental Health, 15 July 2008

Cite This Page:

BioMed Central/Environmental Health. "Women Exposed To High Levels of Pollutant PCB More Likely To Give Birth To Female Children." ScienceDaily. ScienceDaily, 16 July 2008. <www.sciencedaily.com/releases/2008/07/080715103959.htm>.
BioMed Central/Environmental Health. (2008, July 16). Women Exposed To High Levels of Pollutant PCB More Likely To Give Birth To Female Children. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2008/07/080715103959.htm
BioMed Central/Environmental Health. "Women Exposed To High Levels of Pollutant PCB More Likely To Give Birth To Female Children." ScienceDaily. www.sciencedaily.com/releases/2008/07/080715103959.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins