Featured Research

from universities, journals, and other organizations

Potential Non-invasive Optical Detection Of Pancreatic Cancer

Date:
October 13, 2008
Source:
Optical Society of America
Summary:
Researchers are investigating whether tissue optical spectroscopy can be employed for early cancer detection in the pancreas during minimally-invasive endoscopic diagnostic procedures.

At the University of Michigan, a multidisciplinary team of researchers is investigating whether tissue optical spectroscopy can be employed for early cancer detection in the pancreas during minimally-invasive endoscopic diagnostic procedures.

Related Articles


Their objective is to help physicians distinguish between cancerous tissue transformations and benign changes in tissues due to different diseases, such as pancreatitis. Doing this can speed correct diagnosis and treatment to produce better patient outcomes. Pancreatic cancer is the fourth leading cause of cancer death in the United States; 95 percent of all patients diagnosed with the disease will die from it, more than half within six months of diagnosis.

“Until better treatment approaches can be developed, the only opportunity to change disease-associated mortality in pancreatic cancer patients is earlier diagnosis,” explains Mary-Ann Mycek, associate professor and associate chair of the Michigan’s Department of Biomedical Engineering. “Current diagnostic methods have not been able to provide accurate diagnoses in early stages of the disease.”

The Michigan team’s goal is to develop an optical method to detect pancreatic cancer in patients at early stages—an advance that could greatly improve the chances of patient survival by meeting the critical, unmet need of accurately differentiating malignant masses from benign pancreatitis. Such improved diagnostic accuracy could also appropriately triage patients, thereby preventing those without cancer from having unnecessary surgery.

To do this, investigators used a multimodal optical spectroscopy approach based on observing reflectance and fluorescence properties of pancreatic tissue samples. Spectral analysis showed significant differences between normal, pancreatitis (inflammation) and cancerous tissues, thus suggesting non-invasive diagnostic possibilities for distinguishing among disease states.

The idea behind optically-based diagnostics is this: in the body, the presence of disease alters tissue properties, such as local biochemistry and structure. Optically-based disease diagnostic techniques can probe microscopic tissue alterations for signatures of disease, thereby leading to non-invasive diagnostics in living patients. Once detected optically, such diseased tissue may be treated. Because optical techniques do not require the removal of tissue, they could represent an advance in patient care over the invasive practice of tissue biopsy.

Medical research is a cornerstone of Frontiers in Optics 2008 (FiO), the 92nd Annual Meeting of the Optical Society (OSA), being held Oct. 19-23 at the Riverside Convention Center in Rochester, N.Y. FiO 2008 will take place alongside Laser Science XXIV, the annual meeting of the American Physical Society’s Division of Laser Science. Presentation FTuK5, “Modeling Reflectance and Fluorescence Spectra of Human Pancreatic Tissues for Cancer Diagnostics,” Oct. 21.


Story Source:

The above story is based on materials provided by Optical Society of America. Note: Materials may be edited for content and length.


Cite This Page:

Optical Society of America. "Potential Non-invasive Optical Detection Of Pancreatic Cancer." ScienceDaily. ScienceDaily, 13 October 2008. <www.sciencedaily.com/releases/2008/10/081010120155.htm>.
Optical Society of America. (2008, October 13). Potential Non-invasive Optical Detection Of Pancreatic Cancer. ScienceDaily. Retrieved April 19, 2015 from www.sciencedaily.com/releases/2008/10/081010120155.htm
Optical Society of America. "Potential Non-invasive Optical Detection Of Pancreatic Cancer." ScienceDaily. www.sciencedaily.com/releases/2008/10/081010120155.htm (accessed April 19, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, April 19, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Our Love Of Puppy Dog Eyes Explained By Science

Our Love Of Puppy Dog Eyes Explained By Science

Newsy (Apr. 17, 2015) Researchers found a spike in oxytocin occurs in both humans and dogs when they gaze into each other&apos;s eyes. Video provided by Newsy
Powered by NewsLook.com
Dr. Oz Under Fire For 'Quack Treatments' Yet Again

Dr. Oz Under Fire For 'Quack Treatments' Yet Again

Newsy (Apr. 17, 2015) Ten doctors signed a letter urging Columbia University to drop Dr. Oz as vice chair of its department of surgery, saying he plugs "quack" treatments. Video provided by Newsy
Powered by NewsLook.com
Scientists Find Link Between Gestational Diabetes And Autism

Scientists Find Link Between Gestational Diabetes And Autism

Newsy (Apr. 17, 2015) Researchers who analyzed data from over 300,000 kids and their mothers say they&apos;ve found a link between gestational diabetes and autism. Video provided by Newsy
Powered by NewsLook.com
Video Messages Help Reassure Dementia Patients

Video Messages Help Reassure Dementia Patients

AP (Apr. 17, 2015) Family members are prerecording messages as part of a unique pilot program at the Hebrew Home in New York. The videos are trying to help victims of Alzheimer&apos;s disease and other forms of dementia break through the morning fog of forgetfulness. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins