Featured Research

from universities, journals, and other organizations

Simple Blood Test Predicts Obesity

Date:
November 2, 2008
Source:
Monell Chemical Senses Center
Summary:
According to new research, the degree of change in blood triglyceride levels following a fatty meal may indicate susceptibility to diet-induced obesity. The findings open doors to new methods of identifying people, including children, who are at risk for becoming obese.

According to new research from the Monell Center, the degree of change in blood triglyceride levels following a fatty meal may indicate susceptibility to diet-induced obesity. The findings open doors to new methods of identifying people, including children, who are at risk for becoming obese.

Triglycerides are a form of fat that is transported in the blood and stored in the body's fat tissues. They are found in foods and also are manufactured by the body.

"These findings suggest we may someday be able to use a simple blood test to identify those at risk for obesity," said senior author Mark Friedman, PhD, a behavioral physiologist at Monell. "The ability to identify more susceptible individuals would make it possible to target obesity-prevention resources on those who need them most."

The global obesity epidemic is thought to be caused in part by consumption of a diet high in fat and carbohydrates, which promotes weight gain. This propensity to gain weight and become obese when consuming a high-fat diet is at least partially controlled by genes, with some individuals gaining more than others while eating the same diet.

In the study, published in the International Journal of Obesity, Friedman and lead author Hong Ji, PhD, screened rats for vulnerability to diet-induced obesity by measuring the increase in blood triglyceride levels following a single high-fat meal. They then fed the rats a diet high in fat over the next four weeks.

The researchers were able to predict which animals would become obese over the four-week period by examining the earlier metabolic response to the high-fat meal: the smaller the triglyceride change, the greater the weight gain.

There currently are no simple biomarkers for predicting susceptibility to diet-induced obesity, and thus no clinical tests that assist physicians in identifying those at risk for becoming obese. The current findings suggest that a change in blood triglyceride levels may someday be used as such a tool.

Future studies will entail a thorough investigation of the mechanism behind differences in the change in blood triglycerides.

"The differences in weight gain associated with high-fat diets indicate that genetically-determined factors contribute to obesity," notes Friedman. "We have shown that these genetic factors are related to the body's ability to burn fat. We now need a better understanding of how this relates to blood triglyceride levels."

Longer term, Friedman, who received a 2008 Guggenheim Fellowship to pursue his studies on diet and obesity, hopes to determine whether such a blood test is predictive of future weight gain in humans.


Story Source:

The above story is based on materials provided by Monell Chemical Senses Center. Note: Materials may be edited for content and length.


Cite This Page:

Monell Chemical Senses Center. "Simple Blood Test Predicts Obesity." ScienceDaily. ScienceDaily, 2 November 2008. <www.sciencedaily.com/releases/2008/10/081031102059.htm>.
Monell Chemical Senses Center. (2008, November 2). Simple Blood Test Predicts Obesity. ScienceDaily. Retrieved October 1, 2014 from www.sciencedaily.com/releases/2008/10/081031102059.htm
Monell Chemical Senses Center. "Simple Blood Test Predicts Obesity." ScienceDaily. www.sciencedaily.com/releases/2008/10/081031102059.htm (accessed October 1, 2014).

Share This



More Mind & Brain News

Wednesday, October 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pregnancy Spacing Could Have Big Impact On Autism Risks

Pregnancy Spacing Could Have Big Impact On Autism Risks

Newsy (Oct. 1, 2014) A new study says children born less than one year and more than five years after a sibling can have an increased risk for autism. Video provided by Newsy
Powered by NewsLook.com
Stopping School Violence

Stopping School Violence

Ivanhoe (Oct. 1, 2014) A trauma doctor steps out of the hospital and into the classroom to teach kids how to calmly solve conflicts, avoiding a trip to the ER. Video provided by Ivanhoe
Powered by NewsLook.com
Pineal Cysts: Debilitating Pain

Pineal Cysts: Debilitating Pain

Ivanhoe (Oct. 1, 2014) A tiny cyst in the brain that can cause debilitating symptoms like chronic headaches and insomnia, and the doctor who performs the delicate surgery to remove them. Video provided by Ivanhoe
Powered by NewsLook.com
Burning Away Brain Tumors

Burning Away Brain Tumors

Ivanhoe (Oct. 1, 2014) Doctors are 'cooking' brain tumors. Hear how this new laser-heat procedure cuts down on recovery time. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins