Featured Research

from universities, journals, and other organizations

People Who Develop Kidney Stones Are At Increased Risk For Chronic Kidney Disease

Date:
November 17, 2008
Source:
American Society of Nephrology
Summary:
Kidney stones may damage the kidneys and lead to chronic kidney disease (CKD), according to a new article. In extreme cases, individuals with CKD caused by kidney stones may even need dialysis or kidney transplants.

Kidney stones may damage the kidneys and lead to chronic kidney disease (CKD), according to a paper being presented at the American Society of Nephrology's 41st Annual Meeting and Scientific Exposition in Philadelphia, Pennsylvania. In extreme cases, individuals with CKD caused by kidney stones may even need dialysis or kidney transplants.

Related Articles


Kidney stones lead to CKD in patients with rare genetic diseases, but it is unclear if they also are an important risk factor for CKD in the general population. In general, researchers have thought that complications of kidney stones can only rarely cause CKD, but studies that have looked at this potential link have been small or have had limited follow-up.

To get a better sense of the role that kidney stones may play in the development of CKD, John Lieske, MD, and his colleagues at the Mayo Clinic in Rochester, Minnesota, studied records of all residents of Olmsted County, MN, over a 20 year span (1984-2003). These data are available through the Rochester Epidemiology Project, a unique and extensive medical documentation system that combines clinical records from the Mayo Clinic and other community providers in the county.

The investigators compared residents diagnosed with kidney stones with individuals without stones, noting who went on to develop CKD as determined by diagnosis codes and laboratory tests. Those with kidney stones were matched 1:3 to controls in the general population so that a total of 4424 stone formers and 10995 controls were identified and followed up, on average, for more than eight years.

The researchers discovered that individuals diagnosed with kidney stones were significantly more likely to subsequently develop CKD. Specifically, stone formers had a 60% greater risk of developing CKD and a 40% increased risk of developing end-stage renal disease (ESRD), the most severe form of CKD.

The study indicates that patients with kidney stones should be carefully evaluated for CKD and its risk factors, and they should be appropriately treated for any that are identified, said Lieske.

Additional studies are needed to determine why patients with kidney stones are at increased risk for CKD. Studies on potential treatment options also are needed, such as studies to determine whether treatments to prevent stone recurrence would reduce risk of further CKD progression.

The study abstract, "Kidney Stones Are Associated with an Increased Risk of Developing Chronic Kidney Disease," (F-FC202) will be presented as part of a Free Communications session on the topic of "Chronic Kidney Disease: Its Prediction, Prevention, and Treatment" on Friday, November 7 at 4:24 p.m. in Room 204 A of the Pennsylvania Convention Center in Philadelphia, PA.


Story Source:

The above story is based on materials provided by American Society of Nephrology. Note: Materials may be edited for content and length.


Cite This Page:

American Society of Nephrology. "People Who Develop Kidney Stones Are At Increased Risk For Chronic Kidney Disease." ScienceDaily. ScienceDaily, 17 November 2008. <www.sciencedaily.com/releases/2008/11/081108155828.htm>.
American Society of Nephrology. (2008, November 17). People Who Develop Kidney Stones Are At Increased Risk For Chronic Kidney Disease. ScienceDaily. Retrieved April 18, 2015 from www.sciencedaily.com/releases/2008/11/081108155828.htm
American Society of Nephrology. "People Who Develop Kidney Stones Are At Increased Risk For Chronic Kidney Disease." ScienceDaily. www.sciencedaily.com/releases/2008/11/081108155828.htm (accessed April 18, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, April 18, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Our Love Of Puppy Dog Eyes Explained By Science

Our Love Of Puppy Dog Eyes Explained By Science

Newsy (Apr. 17, 2015) Researchers found a spike in oxytocin occurs in both humans and dogs when they gaze into each other&apos;s eyes. Video provided by Newsy
Powered by NewsLook.com
Dr. Oz Under Fire For 'Quack Treatments' Yet Again

Dr. Oz Under Fire For 'Quack Treatments' Yet Again

Newsy (Apr. 17, 2015) Ten doctors signed a letter urging Columbia University to drop Dr. Oz as vice chair of its department of surgery, saying he plugs "quack" treatments. Video provided by Newsy
Powered by NewsLook.com
Scientists Find Link Between Gestational Diabetes And Autism

Scientists Find Link Between Gestational Diabetes And Autism

Newsy (Apr. 17, 2015) Researchers who analyzed data from over 300,000 kids and their mothers say they&apos;ve found a link between gestational diabetes and autism. Video provided by Newsy
Powered by NewsLook.com
Video Messages Help Reassure Dementia Patients

Video Messages Help Reassure Dementia Patients

AP (Apr. 17, 2015) Family members are prerecording messages as part of a unique pilot program at the Hebrew Home in New York. The videos are trying to help victims of Alzheimer&apos;s disease and other forms of dementia break through the morning fog of forgetfulness. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins