Featured Research

from universities, journals, and other organizations

First At-home Test For Vasectomized Men Proves To Be Safe And Accurate, Study Finds

Date:
November 18, 2008
Source:
University of Virginia Health System
Summary:
In a new report, researchers have confirmed the accuracy and reliability of SpermCheck Vasectomy, the first FDA approved at-home immunodiagnostic test for detecting low concentrations of sperm.

In a report now available online and scheduled to be the cover story of the December 2008 issue of the Journal of Urology, University of Virginia Health System researcher John C. Herr, PhD and his colleagues have confirmed the accuracy and reliability of SpermCheck Vasectomy, the first FDA approved at-home immunodiagnostic test for detecting low concentrations of sperm.

Herr, a professor of Cell Biology and director of UVA's Center for Research in Contraceptive and Reproductive Health, discovered and patented the biomarker on which SpermCheck is based. The newly reported research consisted of a clinical trial and consumer study.

In the clinical trial, researchers used SpermCheck to evaluate a cohort of 144 post-vasectomy semen samples. The test achieved an accuracy rate of 96 percent in identifying whether sperm counts were greater or less than a threshold of 250,000 sperm per ml - a level associated with little or no risk of causing pregnancy. SpermCheck proved to be 100 percent accurate in identifying whether sperm counts were greater or less than 384,000 sperm per ml.

According to the World Health Organization Manual on Semen Analysis, normal sperm counts range from 20,000,000/ml to as high as 200,000,000/ml. When the count is below 1,000,000/ml, there is only a remote chance of achieving pregnancy without assisted reproductive techniques such as intra-uterine insemination, in-vitro fertilization and intra-cytoplasmic sperm injection.

In the consumer study of SpermCheck, 109 lay volunteers demonstrated its ease of use. Volunteers obtained the correct or expected test result in every case and achieved a 97 percent correct response rate on a 20-question survey about the test.

Herr, who is now involved in commercializing SpermCheck through a start-up company, believes the product will make it easier for men to comply with post-vasectomy monitoring. Traditionally, the process has involved bringing semen samples to a physician's office or laboratory at two- and three-month intervals after the procedure. Monitoring is important because vasectomies are not 100 percent successful, and men who have had them can experience recanalization, or the spontaneous healing or restoration of the vas deferens, which restores their fertility.

"SpermCheck Vasectomy is similar in size and function to a women's home pregnancy test," Herr says. "It's designed to help couples monitor and confirm that post-vasectomy sperm concentrations have reached infertile levels and avoid any surprises if recanalization occurs."

According to the National Institutes of Child Health and Human Development, some 500,000 men undergo vasectomies in the U.S. each year, making vasectomy the third most popular contraceptive option among the nation's married couples. The National Institutes of Health reports that one in six men over age 35 have had a vasectomy.


Story Source:

The above story is based on materials provided by University of Virginia Health System. Note: Materials may be edited for content and length.


Journal Reference:

  1. Klotz et al. Clinical and Consumer Trial Performance of a Sensitive Immunodiagnostic Home Test That Qualitatively Detects Low Concentrations of Sperm Following Vasectomy. The Journal of Urology, 2008; 180 (6): 2569-2576 [link]

Cite This Page:

University of Virginia Health System. "First At-home Test For Vasectomized Men Proves To Be Safe And Accurate, Study Finds." ScienceDaily. ScienceDaily, 18 November 2008. <www.sciencedaily.com/releases/2008/11/081113181322.htm>.
University of Virginia Health System. (2008, November 18). First At-home Test For Vasectomized Men Proves To Be Safe And Accurate, Study Finds. ScienceDaily. Retrieved August 29, 2014 from www.sciencedaily.com/releases/2008/11/081113181322.htm
University of Virginia Health System. "First At-home Test For Vasectomized Men Proves To Be Safe And Accurate, Study Finds." ScienceDaily. www.sciencedaily.com/releases/2008/11/081113181322.htm (accessed August 29, 2014).

Share This




More Health & Medicine News

Friday, August 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Killer Amoeba Found in Louisiana Water System

Killer Amoeba Found in Louisiana Water System

AP (Aug. 28, 2014) State health officials say testing has confirmed the presence of a killer amoeba in a water system serving three St. John the Baptist Parish towns. (Aug. 28) Video provided by AP
Powered by NewsLook.com
Who Could Be Burnt by WHO's E-Cigs Move?

Who Could Be Burnt by WHO's E-Cigs Move?

Reuters - Business Video Online (Aug. 28, 2014) The World Health Organisation has called for the regulation of electronic cigarettes as both tobacco and medical products. Ciara Lee looks at the impact of the move on the tobacco industry. Video provided by Reuters
Powered by NewsLook.com
CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

Newsy (Aug. 28, 2014) CDC director Tom Frieden says the Ebola outbreak is even worse than he feared. But he also said there's still hope to contain it. Video provided by Newsy
Powered by NewsLook.com
How A 'Rule Of Thumb' Could Slow Down Drinking

How A 'Rule Of Thumb' Could Slow Down Drinking

Newsy (Aug. 28, 2014) A study suggests people who follow a "rule of thumb" when pouring wine dispense less than those who don't have a particular amount in mind. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins