New! Sign up for our free email newsletter.
Reference Terms
from Wikipedia, the free encyclopedia

Pap smear

In gynecology, the Papanikolaou test or Papanicolaou test (also called Pap smear, Pap test, cervical smear, or smear test) is a medical screening method for detecting infectious, premalignant, and malignant processes in the ectocervix, endocervix and endometrium. The pre-cancerous changes (called dysplasias or cervical or endocervical intraepithelial neoplasia) are usually caused by sexually transmitted human papillomaviruses (HPVs). The test aims to detect and prevent the progression of HPV-induced cervical cancer and other abnormalities in the female genital tract by sampling cells from the outer opening of the cervix of the uterus and the endocervix.

Related Stories
 


Health & Medicine News

November 30, 2025

Researchers found that fructose can prime immune cells to overreact to bacterial toxins. In healthy adults, fructose-sweetened drinks increased receptors that trigger inflammation. This heightened sensitivity may contribute to greater infection ...
Researchers at UC Riverside have uncovered why soybean oil, one of America's most widely consumed ingredients, drives significant weight gain—at least in mice. The findings point not to the oil itself but to the fat-derived molecules it produces ...
Scientists have uncovered how too much sunlight can flip a hidden switch inside skin cells that makes inflammation spiral out of control and increases the risk of cancer. Their research reveals that UV radiation breaks down a protective protein ...
Scientists found that RSV infection early in life can set the stage for childhood asthma, particularly in kids already genetically prone to allergies. The virus appears to skew the developing immune system toward exaggerated responses to everyday ...
Researchers have found that ongoing thyroid hormone imbalance in pregnancy may be linked to higher autism risk in children. Treated thyroid disorders did not show the same effect. The longer the imbalance lasted across trimesters, the more the risk ...
Millions face Medicare decisions each year, but many don’t take advantage of tools that can save them money and stress. Insurance marketing often overshadows unbiased options like SHIP, leaving people unaware of better choices. Comparing real ...
Scientists have identified new anti-aging compounds produced by a little-studied blood bacterium. These indole metabolites were able to reduce inflammation, oxidative stress, and collagen-damaging activity in skin cell cultures. Three of the ...
Researchers analyzed data from over six million people to see how close residents lived to cannabis retailers. Neighborhoods near these shops experienced higher cannabis-related emergency visits compared with those farther away. The effect was ...
Researchers found that repeated head impacts can disrupt a key system that helps the brain wash away waste. In professional fighters, this system initially seems to work harder after trauma, then declines over time. MRI scans revealed that these ...
A large-scale Brazilian study found dangerous levels of toxic metals in popular children’s toys, with barium and lead topping the list. Researchers used sophisticated lab methods to identify 21 hazardous elements and test how easily they could be ...
A major review across 73 countries finds that access to antiseizure medications is rising, but safe prescribing isn’t keeping pace. Valproate—linked to serious birth defects—remains widely used in many regions despite WHO warnings. Limited ...
Data from over 47,000 dogs reveal that CBD is most often used in older pets with chronic health issues. Long-term CBD use was linked to reduced aggression, though other anxious behaviors didn’t improve. The trend was strongest among dogs whose ...

Latest Headlines

updated 12:56 pm ET