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Faster Test For Food Protein That Triggers Celiac Disease

Date:
November 21, 2008
Source:
American Chemical Society
Summary:
Researchers are reporting development of a faster test for identifying the food protein that triggers celiac disease, a difficult-to-diagnose digestive disease involving the inability to digest protein called gluten that occurs in wheat, oats, rye, and barley. The finding could help millions of people avoid diarrhea, bloating, and other symptoms that occur when they unknowingly eat foods containing gluten.

Researchers in Spain and the United Kingdom are reporting development of a faster test for identifying the food protein that triggers celiac disease, a difficult-to-diagnose digestive disease involving the inability to digest protein called gluten that occurs in wheat, oats, rye, and barley. The finding could help millions of people avoid diarrhea, bloating, and other symptoms that occur when they unknowingly eat foods containing gluten.

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In the new report, Alex Fragoso, Ciara O'Sullivan and colleagues note that patients with celiac disease can avoid symptoms by avoiding foods that contain gluten. Doing so can be tricky, however, because gluten may be a hidden ingredient in unsuspected foods, such as soy sauce, canned soups, and licorice candy. Some prepared foods list gluten content on package labels, but identifying its presence remains difficult and time-consuming.

The scientists describe development of a new sensor that detects antibodies to the protein gliadin, a component of gluten. Laboratory tests showed that it is superior to the so-called enzyme-linked immunosorbent assay (ELISA), now the standard test for gliadin. It took the new test barely 90 minutes to detect gliadin in the parts per billion range, compared to 8 hours for the ELISA test. Although both tests were equally accurate, the new sensor would be easier to use at food manufacturing plants, the researchers note.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Nassef et al. Electrochemical Immunosensor for Detection of Celiac Disease Toxic Gliadin in Foodstuff. Analytical Chemistry, 2008 DOI: 10.1021/ac801620j

Cite This Page:

American Chemical Society. "Faster Test For Food Protein That Triggers Celiac Disease." ScienceDaily. ScienceDaily, 21 November 2008. <www.sciencedaily.com/releases/2008/11/081117095103.htm>.
American Chemical Society. (2008, November 21). Faster Test For Food Protein That Triggers Celiac Disease. ScienceDaily. Retrieved February 1, 2015 from www.sciencedaily.com/releases/2008/11/081117095103.htm
American Chemical Society. "Faster Test For Food Protein That Triggers Celiac Disease." ScienceDaily. www.sciencedaily.com/releases/2008/11/081117095103.htm (accessed February 1, 2015).

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