Featured Research

from universities, journals, and other organizations

Nearly Three-quarters Of Youths With Diabetes Insufficient In Vitamin D

Date:
December 19, 2008
Source:
Joslin Diabetes Center
Summary:
Three-quarters of youths with type 1 diabetes were found to have insufficient levels of vitamin D, according to a new study -- findings that suggest children with the disease may need vitamin D supplementation to prevent bone fragility later in life.

Three-quarters of youths with type 1 diabetes were found to have insufficient levels of vitamin D, according to a study by researchers at the Joslin Diabetes Center – findings that suggest children with the disease may need vitamin D supplementation to prevent bone fragility later in life.

Related Articles


"To our surprise, we found extremely high rates of vitamin D inadequacy," said Lori Laffel, M.D., M.P.H., Chief of the Pediatric, Adolescent and Young Adult Section at Joslin, Investigator in the Section on Genetics and Epidemiology, and senior author of the paper. "We didn't expect to find that only 24 percent of the study population would have adequate levels."

The study, which appears in the January 2009 issue of The Journal of Pediatrics, measured levels of serum 25-hydroxyvitamin D in 128 youths with type 1 diabetes ranging in age from 1.5 to 17.5 years. The study sample included subjects with recent onset of diabetes as well as those who had long-established diabetes.

It found 24 percent had sufficient levels, 61 percent with insufficient levels and 15 percent to be deficient or having the lowest levels. Generally, those with deficient levels were the oldest of the subjects. In fact, 85 percent of the adolescents in the sample demonstrated inadequate vitamin D levels.

The paper notes that diabetes itself can negatively impact bone health and is associated with a modest reduction in bone mineral density and strength and an increase in fracture risk among those middle-aged and older. At the same time, vitamin D deficiency in infants and children is associated with bone deformation, while less severe vitamin D insufficiency prevents youths from attaining their optimal bone mass and may contribute to increased fracture risk later in life, the paper adds.

For these reasons, vitamin D deficiency or insufficiency poses an increased risk for children with diabetes, the paper says. In addition to reduced sun exposure, diminished milk intake, substituted by intake of sugar-free beverages among youth with diabetes, may account for inadequate vitamin D levels.

"In addition to inadequate levels of vitamin D, adolescent patients with type 1 diabetes potentially possess multiple risk factors for increased skeletal fragility," the paper notes.

The researchers were interested in looking at vitamin D levels because of the vitamin's presumed role in immune modulation and because it is thought to possibly play a role in the occurrence of type 1 diabetes.

In addition, there has been a rise in vitamin D deficiency among children in general, mostly among those living in northern climates where sun exposure is lowest, and also in association with the increased use of sun block, recommended in efforts to prevent skin cancer. Protection from over-exposure to sunlight through use of sunscreens remains an important public health initiative, Laffel stressed.

"We need to make sure all youths in general are getting enough vitamin D in their diets," commented Britta Svoren, M.D., the primary author of the paper and a member of Joslin's Pediatric, Adolescent and Young Adult Section and the Section on Genetics and Epidemiololgy. "And, we need to pay particular attention to those with diabetes as they appear to be at an even higher risk of vitamin D deficiency. For children who are not drinking sufficient amounts of vitamin D fortified milk, we are encouraging them to take a vitamin D supplement of 400 IU daily. Many cereals are fortified with vitamin D as well."

The study was funded by the National Institutes of Health, the Charles H. Hood Foundation and a Pediatric Fellowship Grant from Eli Lilly and Company.

Also contributing to the research were Lisa K. Volkening, M.A. and Jamie R. Wood, M.D., both of Joslin.


Story Source:

The above story is based on materials provided by Joslin Diabetes Center. Note: Materials may be edited for content and length.


Cite This Page:

Joslin Diabetes Center. "Nearly Three-quarters Of Youths With Diabetes Insufficient In Vitamin D." ScienceDaily. ScienceDaily, 19 December 2008. <www.sciencedaily.com/releases/2008/12/081215121605.htm>.
Joslin Diabetes Center. (2008, December 19). Nearly Three-quarters Of Youths With Diabetes Insufficient In Vitamin D. ScienceDaily. Retrieved March 29, 2015 from www.sciencedaily.com/releases/2008/12/081215121605.htm
Joslin Diabetes Center. "Nearly Three-quarters Of Youths With Diabetes Insufficient In Vitamin D." ScienceDaily. www.sciencedaily.com/releases/2008/12/081215121605.htm (accessed March 29, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, March 29, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
WH Plan to Fight Antibiotic-Resistant Germs

WH Plan to Fight Antibiotic-Resistant Germs

AP (Mar. 27, 2015) The White House on Friday announced a five-year plan to fight the threat posed by antibiotic-resistant bacteria amid fears that once-treatable germs could become deadly. (March 27) Video provided by AP
Powered by NewsLook.com
House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins