Featured Research

from universities, journals, and other organizations

Abnormal EKG Can Predict Death In Stroke Patients

Date:
March 25, 2009
Source:
University of Rochester Medical Center
Summary:
People who suffer an ischemic stroke and also have an abnormality in the heart's electrical cycle are at a higher risk of death within 90 days than people who do not have abnormal electrical activity at the time of emergency treatment, according to new research.

People who suffer an ischemic stroke and also have an abnormality in the heart's electrical cycle are at a higher risk of death within 90 days than people who do not have abnormal electrical activity at the time of emergency treatment, according to new research.

The study also provides a threshold at which the threat of death is highest: QTc intervals greater than 440 milliseconds in women and 438 milliseconds in men have the worst prognosis. The findings are published online March 20, 2009, in the Journal of Stroke and Cerebrovascular Diseases.

"From a clinical perspective, our study offers additional parameters to consider while treating stroke patients in the Emergency Department setting,' said corresponding author Latha G. Stead, M.D., professor and chair of the Department of Emergency Medicine at the University of Rochester Medical Center, who recently joined the URMC from the Mayo Clinic. "It appears that reviewing the medications a patient is taking and looking specifically for those that might prolong the QTc interval would be a useful practice."

The QTc interval is a measure of the electrical activity of the heart. An EKG records the waves of activity and its pattern, which is labeled with letters Q and T. Doctors look for the appropriate intervals between each letter, showing that the heart's electrical signals are steadily passing through the ventricles. A prolonged QTc interval means it takes too long for the electrical signal to pass.

Prolonged QTc intervals can be the result of a rare genetic disorder, medications, electrolyte imbalances, or congenital heart disease. Scientific data on the relationship between abnormal QTc intervals and death has been inconsistent, and few studies have looked at this relationship in the context of acute ischemic stroke, Stead said.

Researchers studied the medical records of 345 ischemic stroke patients at the Mayo Clinic, treated between 2001 and 2004, and followed for 90 days. Further analysis was done to see if the researchers could identify a QTc cutoff that would accurately predict death within 90 days.

About 35 percent of the patients had a prolonged QTc interval at the time of the emergency department visit. An estimated 81 percent of all patients were expected to survive the next three months. However, results showed that only 70.5 percent of the patients with a prolonged QTc interval survived compared with 87.1percent of the patients without a prolonged QTc interval.

In addition, researchers found that although the causes of death ranged from stroke to cardiac illnesses to cancer and respiratory failure, most patients died of stroke or cardiac causes. In those cases, about half of the patients had prolonged QTc intervals. Among the stroke survivors, patients with prolonged QT intervals had poorer functional outcomes.

About 795,000 Americans each year suffer a new or recurrent stroke. That means, on average, a stroke occurs every 40 seconds, according to the American Stroke Association. Ischemic strokes, obstructions of the blood vessels supplying blood to the brain, account for the majority of cases.

Stead is supported by the Mayo Foundation Emergency Medicine Career Research Career Development Award.


Story Source:

The above story is based on materials provided by University of Rochester Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

University of Rochester Medical Center. "Abnormal EKG Can Predict Death In Stroke Patients." ScienceDaily. ScienceDaily, 25 March 2009. <www.sciencedaily.com/releases/2009/03/090320092104.htm>.
University of Rochester Medical Center. (2009, March 25). Abnormal EKG Can Predict Death In Stroke Patients. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2009/03/090320092104.htm
University of Rochester Medical Center. "Abnormal EKG Can Predict Death In Stroke Patients." ScienceDaily. www.sciencedaily.com/releases/2009/03/090320092104.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins