Featured Research

from universities, journals, and other organizations

Male Circumcision Reduces HIV Risk: No Further Evidence Needed, According To Review

Date:
April 15, 2009
Source:
Wiley - Blackwell
Summary:
Three recent African trials support male circumcision for reducing the risk of contracting HIV in heterosexual men. After including new data from these trials in their review, researchers have changed their previous conclusions that there was insufficient evidence to recommend circumcision as an intervention to prevent HIV infection in heterosexual men.

Three recent African trials support male circumcision for reducing the risk of contracting HIV in heterosexual men. After including new data from these trials in their review, Cochrane Researchers have changed their previous conclusions that there was insufficient evidence to recommend circumcision as an intervention to prevent HIV infection in heterosexual men.

Related Articles


"Research on the effectiveness of male circumcision for preventing HIV in heterosexual men is conclusive. No further trials are required to establish that HIV infection rates are reduced in heterosexual men for at least the first two years after circumcision," says lead researcher Nandi Siegfried, Co-director of the South African Cochrane Centre at the South African Medical Research Council. "Policy makers can consider implementing circumcision as an additional measure into HIV prevention programmes."

Circumcision may help to protect against HIV by removing cells in the foreskin to which the virus is specifically attracted. Called Langerhans cells, they display receptors that enable HIV entry. Previous non-randomised studies investigated the association between circumcision and HIV, but until now, Cochrane researchers have been unable to make strong recommendations for the intervention due to a lack of high quality evidence gained from randomised clinical trials.

The clinical trials included in the review took place in South Africa, Uganda, and Kenya between 2002 and 2006, and included a total of 11,054 men. The results show that circumcision in heterosexual men significantly reduces their risk of acquiring HIV by 54% over a two year period, compared with uncircumcised men. This reduced risk is the best estimate of the average effect and the researchers report that the true risk will be reduced by between 38 to 66%. Further research, however, is required to establish whether male circumcision offers any benefit to women partners of circumcised men and homosexual men.

The researchers warn that policy makers also need to think about the culture and environment in which circumcision is carried out. "In many countries, male circumcision is practiced as part of the rites of initiation by traditional healers who are not trained in aseptic surgical techniques. So adverse events following traditional circumcisions can be high," says Siegfried.


Story Source:

The above story is based on materials provided by Wiley - Blackwell. Note: Materials may be edited for content and length.


Journal Reference:

  1. Siegfried et al. Male circumcision for prevention of heterosexual acquisition of HIV in men. Cochrane Database of Systematic Reviews Reviews, 2009, Issue 2. Art. No.: CD003362 DOI: 10.1002/14651858.CD003362.pub2

Cite This Page:

Wiley - Blackwell. "Male Circumcision Reduces HIV Risk: No Further Evidence Needed, According To Review." ScienceDaily. ScienceDaily, 15 April 2009. <www.sciencedaily.com/releases/2009/04/090415074940.htm>.
Wiley - Blackwell. (2009, April 15). Male Circumcision Reduces HIV Risk: No Further Evidence Needed, According To Review. ScienceDaily. Retrieved March 6, 2015 from www.sciencedaily.com/releases/2009/04/090415074940.htm
Wiley - Blackwell. "Male Circumcision Reduces HIV Risk: No Further Evidence Needed, According To Review." ScienceDaily. www.sciencedaily.com/releases/2009/04/090415074940.htm (accessed March 6, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, March 6, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Suicide Rates Up For Young Women In U.S.

Suicide Rates Up For Young Women In U.S.

Newsy (Mar. 6, 2015) According to a report from the CDC, suicide rates among young women increased from 1994 to 2012 while rates among young men have decreased. Video provided by Newsy
Powered by NewsLook.com
Bupa Eyes India Healthcare Opportunities

Bupa Eyes India Healthcare Opportunities

Reuters - Business Video Online (Mar. 5, 2015) Bupa is hoping to expand in India&apos;s fast-growing health insurance market, once a rule change on foreign investment is implemented. The British private healthcare group&apos;s CEO tells Grace Pascoe why it&apos;s so keen on the new opportunity. Video provided by Reuters
Powered by NewsLook.com
Liberia Releases Last Ebola Patient, But Threat Remains

Liberia Releases Last Ebola Patient, But Threat Remains

Newsy (Mar. 5, 2015) Liberia&apos;s last Ebola patient has been released, and the country hasn&apos;t recorded a new case in a week. However, fears of another outbreak still exist. Video provided by Newsy
Powered by NewsLook.com
Doctor in Your Pocket Is Getting Smarter

Doctor in Your Pocket Is Getting Smarter

Reuters - Business Video Online (Mar. 5, 2015) Mobile apps are turning smartphones into a personal doctors, with users able to measure heart rate, blood pressure and even blood sugar. But will it change our behaviour? Ivor Bennett reports from the Mobile World Congress in Barcelona. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins