Featured Research

from universities, journals, and other organizations

At Risk For Kidney Disease? Check Your Genes

Date:
April 19, 2009
Source:
American Society of Nephrology
Summary:
Genetic differences can influence one's risk of developing proteinuria, a condition that increases the risk of cardiovascular disease and chronic kidney disease, according to a new study. The results may be important for determining patients' health risks and for devising new medical treatments.

Genetic differences can influence one's risk of developing proteinuria, a condition that increases the risk of cardiovascular disease and chronic kidney disease (CKD), according to a new study. The results may be important for determining patients' health risks and for devising new medical treatments.

Approximately 12% of people in the United States have proteinuria (abnormal levels of protein lost in the urine), and African Americans and American Indians have higher risks of developing the condition than other groups. Researchers suspect that genetic variation likely accounts for part of their increased risks.

Amy Mottl, MD (University of North Carolina Kidney Center), and her colleagues looked to see if they could identify the genetic causes of American Indians' increased risk for proteinuria. They studied approximately 3,500 individuals from 13 American Indian tribes enrolled in the Strong Heart Family Study funded by the National Heart, Lung and Blood Institute. The investigators found multiple chromosomal regions that may possess genes that influence variation in proteinuria, especially in the setting of diabetes or hypertension.

The study's findings are preliminary and additional research is needed to determine which genes influence one's proteinuria risk. "Further exploration of the candidate genes underlying the chromosomes implicated in our study is warranted," the authors wrote. This could lead to a better understanding of how proteinuria arises and to the development of new strategies for prevention and treatment.

While this study focused on American Indians, its findings likely apply to the general population as well, where the prevalence of proteinuria is rising.

The authors report no financial disclosures.


Story Source:

The above story is based on materials provided by American Society of Nephrology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Linkage Analysis of Albuminuria. Journal of the American Society of Nephrology, April 15, 2009 DOI: 10.1681/ASN.2008080895

Cite This Page:

American Society of Nephrology. "At Risk For Kidney Disease? Check Your Genes." ScienceDaily. ScienceDaily, 19 April 2009. <www.sciencedaily.com/releases/2009/04/090415172233.htm>.
American Society of Nephrology. (2009, April 19). At Risk For Kidney Disease? Check Your Genes. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2009/04/090415172233.htm
American Society of Nephrology. "At Risk For Kidney Disease? Check Your Genes." ScienceDaily. www.sciencedaily.com/releases/2009/04/090415172233.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins