Featured Research

from universities, journals, and other organizations

At Risk For Kidney Disease? Check Your Genes

Date:
April 19, 2009
Source:
American Society of Nephrology
Summary:
Genetic differences can influence one's risk of developing proteinuria, a condition that increases the risk of cardiovascular disease and chronic kidney disease, according to a new study. The results may be important for determining patients' health risks and for devising new medical treatments.

Genetic differences can influence one's risk of developing proteinuria, a condition that increases the risk of cardiovascular disease and chronic kidney disease (CKD), according to a new study. The results may be important for determining patients' health risks and for devising new medical treatments.

Related Articles


Approximately 12% of people in the United States have proteinuria (abnormal levels of protein lost in the urine), and African Americans and American Indians have higher risks of developing the condition than other groups. Researchers suspect that genetic variation likely accounts for part of their increased risks.

Amy Mottl, MD (University of North Carolina Kidney Center), and her colleagues looked to see if they could identify the genetic causes of American Indians' increased risk for proteinuria. They studied approximately 3,500 individuals from 13 American Indian tribes enrolled in the Strong Heart Family Study funded by the National Heart, Lung and Blood Institute. The investigators found multiple chromosomal regions that may possess genes that influence variation in proteinuria, especially in the setting of diabetes or hypertension.

The study's findings are preliminary and additional research is needed to determine which genes influence one's proteinuria risk. "Further exploration of the candidate genes underlying the chromosomes implicated in our study is warranted," the authors wrote. This could lead to a better understanding of how proteinuria arises and to the development of new strategies for prevention and treatment.

While this study focused on American Indians, its findings likely apply to the general population as well, where the prevalence of proteinuria is rising.

The authors report no financial disclosures.


Story Source:

The above story is based on materials provided by American Society of Nephrology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Linkage Analysis of Albuminuria. Journal of the American Society of Nephrology, April 15, 2009 DOI: 10.1681/ASN.2008080895

Cite This Page:

American Society of Nephrology. "At Risk For Kidney Disease? Check Your Genes." ScienceDaily. ScienceDaily, 19 April 2009. <www.sciencedaily.com/releases/2009/04/090415172233.htm>.
American Society of Nephrology. (2009, April 19). At Risk For Kidney Disease? Check Your Genes. ScienceDaily. Retrieved February 28, 2015 from www.sciencedaily.com/releases/2009/04/090415172233.htm
American Society of Nephrology. "At Risk For Kidney Disease? Check Your Genes." ScienceDaily. www.sciencedaily.com/releases/2009/04/090415172233.htm (accessed February 28, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, February 28, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Reuters - Innovations Video Online (Feb. 27, 2015) A dongle that plugs into a Smartphone mimics a lab-based blood test for HIV and syphilis and can detect the diseases in 15 minutes, say researchers. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com
Doctor Says Head Transplants Possible Within Two Years

Doctor Says Head Transplants Possible Within Two Years

Buzz60 (Feb. 27, 2015) An Italian doctor is saying he could stick someone&apos;s head onto someone else&apos;s body. Patrick Jones (@Patrick_E_Jones) reports. Video provided by Buzz60
Powered by NewsLook.com
How Your Dentist Could Help Screen You For Diabetes

How Your Dentist Could Help Screen You For Diabetes

Newsy (Feb. 27, 2015) A new study from researchers at New York University suggests dentists could soon use blood samples taken from patients&apos; mouths to test for diabetes. Video provided by Newsy
Powered by NewsLook.com
The Best Tips to Makeover Your Health

The Best Tips to Makeover Your Health

Buzz60 (Feb. 27, 2015) If you&apos;re looking to boost your health this season, there are a few quick and easy steps to prompt you for success. Krystin Goodwin (@Krystingoodwin) has the best tips to give your health a makeover this spring! Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins