Featured Research

from universities, journals, and other organizations

New Tool Can Help Predict Risk Of Alzheimer's In Elderly

Date:
May 18, 2009
Source:
American Academy of Neurology
Summary:
A new tool can help predict whether people age 65 and older have a high risk of developing Alzheimer's disease.

A new tool can help predict whether people age 65 and older have a high risk of developing Alzheimer's disease. Research on the tool is published in the May 13, 2009, online issue of Neurology, the medical journal of the American Academy of Neurology.

"This new risk index could be very important both for research and for people at risk of developing dementia and their families," said study author Deborah E. Barnes, PhD, MPH, of the University of California, San Francisco, San Francisco Veterans Affairs Medical Center and member of the American Academy of Neurology. "It could be used to identify people at high risk for dementia for studies on new drugs or prevention methods. The tool could also identify people who have no signs of dementia but should be monitored closely, allowing them to begin treatment as soon as possible, and potentially helping them maintain their thinking and memory skills and quality of life longer."

The risk index is a 15-point scale. People who score eight or more points on the scale are at high risk of developing dementia in the next six years. Several of the items on the scale are well-known risk factors for Alzheimer's disease, such as older age, low scores on tests of thinking skills, and having a gene that has been linked to the disease.

Other factors predicting dementia risk were more surprising: People who are underweight, do not drink alcohol, have had coronary bypass surgery, or are slow at performing physical tasks such as buttoning a shirt are more likely to develop dementia than people who do not have these risk factors.

To develop the index, researchers in the Cardiovascular Health Study examined 3,375 people with an average age of 76 and no evidence of dementia and followed them for six years. During that time, 480 of the people, or 14 percent, developed dementia. The researchers then determined which factors best predicted who would develop dementia and created the point index.

A total of 56 percent of those with high scores on the index developed dementia, compared to 23 percent of those with moderate scores and four percent of those with low scores. Overall, the index correctly classified 88 percent of the participants.

Barnes said the risk index will need to be validated with other studies, and she and her colleagues are evaluating whether a shorter, more simplified index could be as accurate as this index.

The study was supported by the National Institutes of Health, the National Heart, Lung, and Blood Institute, the National Institute on Aging, and the National Institute of Neurological Disorders and Stroke.


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Neurology. "New Tool Can Help Predict Risk Of Alzheimer's In Elderly." ScienceDaily. ScienceDaily, 18 May 2009. <www.sciencedaily.com/releases/2009/05/090513173450.htm>.
American Academy of Neurology. (2009, May 18). New Tool Can Help Predict Risk Of Alzheimer's In Elderly. ScienceDaily. Retrieved July 30, 2014 from www.sciencedaily.com/releases/2009/05/090513173450.htm
American Academy of Neurology. "New Tool Can Help Predict Risk Of Alzheimer's In Elderly." ScienceDaily. www.sciencedaily.com/releases/2009/05/090513173450.htm (accessed July 30, 2014).

Share This




More Health & Medicine News

Wednesday, July 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Concern Grows Over Worsening Ebola Crisis

Concern Grows Over Worsening Ebola Crisis

AFP (July 30, 2014) Pan-African airline ASKY has suspended all flights to and from the capitals of Liberia and Sierra Leone amid the worsening Ebola health crisis, which has so far caused 672 deaths in Guinea, Liberia and Sierra Leone. Duration: 00:43 Video provided by AFP
Powered by NewsLook.com
At Least 20 Chikungunya Cases in New Jersey

At Least 20 Chikungunya Cases in New Jersey

AP (July 30, 2014) At least 20 New Jersey residents have tested positive for chikungunya, a mosquito-borne virus that has spread through the Caribbean. (July 30) Video provided by AP
Powered by NewsLook.com
Generics Eat Into Pfizer's Sales

Generics Eat Into Pfizer's Sales

Reuters - Business Video Online (July 29, 2014) Pfizer, the world's largest drug maker, cut full-year revenue forecasts because generics could cut into sales of its anti-arthritis drug, Celebrex. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins