Featured Research

from universities, journals, and other organizations

Progress Toward Artificial Tissue?

Date:
May 16, 2009
Source:
Wiley-Blackwell
Summary:
Researchers have developed a novel, highly porous, sponge-like material whose mechanical properties closely resemble those of biological soft tissues.

A team of Australian and Korean researchers led by Geoffrey M. Spinks and Seon Jeong Kim has now developed a novel, highly porous, sponge-like material whose mechanical properties closely resemble those of biological soft tissues. It consists of a robust network of DNA strands and carbon nanotubes.
Credit: Copyright Wiley-VCH

For modern implants and the growth of artificial tissue and organs, it is important to generate materials with characteristics that closely emulate nature. However, the tissue in our bodies has a combination of traits that are very hard to recreate in synthetic materials: It is both soft and very tough.

A team of Australian and Korean researchers led by Geoffrey M. Spinks and Seon Jeong Kim has now developed a novel, highly porous, sponge-like material whose mechanical properties closely resemble those of biological soft tissues. It consists of a robust network of DNA strands and carbon nanotubes.

Soft tissues, such as tendons, muscles, arteries, and skin or other organs, obtain their mechanical support from the extracellular matrix, a network of protein-based nanofibers. Different protein morphologies in the extracellular matrix produce tissue with a wide range of stiffness. Implants and scaffolding for tissue growth require porous, soft materials -- which are usually very fragile. Because many biological tissues are regularly subjected to intense mechanical loads, it is also important that the implant material have comparable elasticity in order to avoid inflammation. At the same time, the material must be very strong and resilient, or it may give out.

The new concept uses DNA strands as a matrix; the strands completely “wrap” the scaffold-forming carbon nanotubes in the presence of an ionic liquid, networking them to form a gel. This gel can be spun: just as silk and synthetic fibers can be wet-spun for textiles, the gel can be made into very fine threads when injected into a special bath. The dried fibers have a porous, sponge-like structure and consist of a network of intertwined 50 nm-wide nanofibers. Soaking in a calcium chloride solution further cross-links the DNA, causing the fibers to become denser and more strongly connected.

These spongy fibers resemble the collagen fiber networks of the biological extracellular matrix. They can also be knotted, braided, or woven into textile-like structures. This results in materials that are as elastic as the softest natural tissues while simultaneously deriving great strength from the robust DNA links.

An additional advantage is the electrical conductivity of the new material, which can thus also be used in electrodes for mechanical actuators, energy storage, and sensors. For example, the researchers were able to produce a hydrogen peroxide sensor. The carbon nanotubes catalyze the oxidation of hydrogen peroxide, which results in a measurable current. Hydrogen peroxide plays a role in normal heart function and certain heart diseases. A robust sensor with elasticity similar to the heart muscle would be of great help in researching these relationships.


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Journal Reference:

  1. Geoffrey M. Spinks, Seon Jeong Kim et al. Tough Supersoft Sponge Fibers with Tunable Stiffness from a DNA Self-Assembly Technique. Angewandte Chemie International Edition, DOI: 10.1002/anie.200804788

Cite This Page:

Wiley-Blackwell. "Progress Toward Artificial Tissue?." ScienceDaily. ScienceDaily, 16 May 2009. <www.sciencedaily.com/releases/2009/05/090515104227.htm>.
Wiley-Blackwell. (2009, May 16). Progress Toward Artificial Tissue?. ScienceDaily. Retrieved October 23, 2014 from www.sciencedaily.com/releases/2009/05/090515104227.htm
Wiley-Blackwell. "Progress Toward Artificial Tissue?." ScienceDaily. www.sciencedaily.com/releases/2009/05/090515104227.htm (accessed October 23, 2014).

Share This



More Matter & Energy News

Thursday, October 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

3D Printed Instruments Make Sweet Music in Sweden

3D Printed Instruments Make Sweet Music in Sweden

Reuters - Innovations Video Online (Oct. 23, 2014) Students from Lund University's Malmo Academy of Music are believed to be the world's first band to all use 3D printed instruments. The guitar, bass guitar, keyboard and drums were built by Olaf Diegel, professor of product development, who says 3D printing allows musicians to design an instrument to their exact specifications. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Chameleon Camouflage to Give Tanks Cloaking Capabilities

Chameleon Camouflage to Give Tanks Cloaking Capabilities

Reuters - Innovations Video Online (Oct. 22, 2014) Inspired by the way a chameleon changes its colour to disguise itself; scientists in Poland want to replace traditional camouflage paint with thousands of electrochromic plates that will continuously change colour to blend with its surroundings. The first PL-01 concept tank prototype will be tested within a few years, with scientists predicting that a similar technology could even be woven into the fabric of a soldiers' clothing making them virtually invisible to the naked eye. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Jet Sales Lift Boeing Profit 18 Pct.

Jet Sales Lift Boeing Profit 18 Pct.

Reuters - Business Video Online (Oct. 22, 2014) Strong jet demand has pushed Boeing to raise its profit forecast for the third time, but analysts were disappointed by its small cash flow. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Internet of Things Aims to Smarten Your Life

Internet of Things Aims to Smarten Your Life

AP (Oct. 22, 2014) As more and more Bluetooth-enabled devices are reaching consumers, developers are busy connecting them together as part of the Internet of Things. (Oct. 22) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins